| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the meropenem-3564 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ACSBG2 | acyl-CoA synthetase bubblegum family member 2 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AFF2 | AF4/FMR2 family, member 2 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BLNK | B-cell linker |
| C3 | complement component 3 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CA1 | carbonic anhydrase I |
| CA4 | carbonic anhydrase IV |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CALML3 | calmodulin-like 3 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCDC57 | coiled-coil domain containing 57 |
| CDK19 | cyclin-dependent kinase 19 |
| CLGN | calmegin |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRMP1 | collapsin response mediator protein 1 |
| CTBP2 | C-terminal binding protein 2 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DRD2 | dopamine receptor D2 |
| EDNRB | endothelin receptor type B |
| EFNB3 | ephrin-B3 |
| EGFR | epidermal growth factor receptor |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPN1 | epsin 1 |
| FAM46C | family with sequence similarity 46, member C |
| FAM76A | family with sequence similarity 76, member A |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXN3 | forkhead box N3 |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GOLGA6A | golgin A6 family, member A |
| GPER1 | G protein-coupled estrogen receptor 1 |
| HDC | histidine decarboxylase |
| HERC2P3 | hect domain and RLD 2 pseudogene 3 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H3E | histone cluster 1, H3e |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA10 | homeobox A10 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGA7 | integrin, alpha 7 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KHK | ketohexokinase (fructokinase) |
| LAMC2 | laminin, gamma 2 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMO1 | LIM domain only 1 (rhombotin 1) |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP25 | matrix metallopeptidase 25 |
| MYOZ1 | myozenin 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NF1 | neurofibromin 1 |
| NRN1 | neuritin 1 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PAX5 | paired box 5 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PQBP1 | polyglutamine binding protein 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PSCA | prostate stem cell antigen |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| RSU1 | Ras suppressor protein 1 |
| S100A1 | S100 calcium binding protein A1 |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporter), member 3 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| STK11 | serine/threonine kinase 11 |
| SVIL | supervillin |
| TBXA2R | thromboxane A2 receptor |
| TENM1 | teneurin transmembrane protein 1 |
| TEX41 | testis expressed 41 (non-protein coding) |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TNMD | tenomodulin |
| TRBC1 | T cell receptor beta constant 1 |
| ULBP1 | UL16 binding protein 1 |
| WT1-AS | WT1 antisense RNA |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF493 | zinc finger protein 493 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACTL8 | actin-like 8 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APOD | apolipoprotein D |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5AR2 | complement component 5a receptor 2 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD82 | CD82 molecule |
| CDC34 | cell division cycle 34 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP85 | centrosomal protein 85kDa |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN9 | claudin 9 |
| COG4 | component of oligomeric golgi complex 4 |
| CORT | cortistatin |
| CPTP | ceramide-1-phosphate transfer protein |
| CUL9 | cullin 9 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DSCAM | Down syndrome cell adhesion molecule |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FAAH | fatty acid amide hydrolase |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FER | fer (fps/fes related) tyrosine kinase |
| GAB2 | GRB2-associated binding protein 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR176 | G protein-coupled receptor 176 |
| H2AFY2 | H2A histone family, member Y2 |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4F | histone cluster 1, H4f |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| INTS9 | integrator complex subunit 9 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KLK5 | kallikrein-related peptidase 5 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMB3 | laminin, beta 3 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEFV | Mediterranean fever |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MYO1F | myosin IF |
| NDE1 | nudE neurodevelopment protein 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PCDHB8 | protocadherin beta 8 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PGP | phosphoglycolate phosphatase |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| PLXNA3 | plexin A3 |
| PRMT7 | protein arginine methyltransferase 7 |
| PTK6 | protein tyrosine kinase 6 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBM42 | RNA binding motif protein 42 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF2 | ring finger protein 2 |
| RNF31 | ring finger protein 31 |
| ROM1 | retinal outer segment membrane protein 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SYCP2 | synaptonemal complex protein 2 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBG2 | tubulin, gamma 2 |
| USB1 | U6 snRNA biogenesis 1 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF408 | zinc finger protein 408 |
| ZNF573 | zinc finger protein 573 |
