| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the meropenem-5824 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ABHD17B | abhydrolase domain containing 17B |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANKRD55 | ankyrin repeat domain 55 |
| AR | androgen receptor |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARMC4 | armadillo repeat containing 4 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BMP5 | bone morphogenetic protein 5 |
| BTC | betacellulin |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CADM1 | cell adhesion molecule 1 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CEP68 | centrosomal protein 68kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLDN18 | claudin 18 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORO2A | coronin, actin binding protein, 2A |
| CTIF | CBP80/20-dependent translation initiation factor |
| CTSF | cathepsin F |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DXO | decapping exoribonuclease |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FAM105A | family with sequence similarity 105, member A |
| FAM182B | family with sequence similarity 182, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FOXN3 | forkhead box N3 |
| FOXO4 | forkhead box O4 |
| GALK2 | galactokinase 2 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HFE | hemochromatosis |
| HGFAC | HGF activator |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| IBSP | integrin-binding sialoprotein |
| ITGB4 | integrin, beta 4 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIF5C | kinesin family member 5C |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAD1 | ladinin 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP2 | microtubule-associated protein 2 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MBTPS1 | membrane-bound transcription factor peptidase, site 1 |
| MPI | mannose phosphate isomerase |
| MVK | mevalonate kinase |
| MXD3 | MAX dimerization protein 3 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NPY | neuropeptide Y |
| OSBPL10 | oxysterol binding protein-like 10 |
| PALMD | palmdelphin |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PITX1 | paired-like homeodomain 1 |
| PLIN2 | perilipin 2 |
| PRMT2IP | PRMT2 interacting protein |
| RAB14 | RAB14, member RAS oncogene family |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RC3H2 | ring finger and CCCH-type domains 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SBF1 | SET binding factor 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa |
| SGSM3 | small G protein signaling modulator 3 |
| SMAD4 | SMAD family member 4 |
| SMAD5 | SMAD family member 5 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SQLE | squalene epoxidase |
| SSH3 | slingshot protein phosphatase 3 |
| STK17B | serine/threonine kinase 17b |
| SUGP1 | SURP and G patch domain containing 1 |
| TAGLN3 | transgelin 3 |
| TBL2 | transducin (beta)-like 2 |
| TEX40 | testis expressed 40 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TXNRD3 | thioredoxin reductase 3 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF408 | zinc finger protein 408 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACTR1B | ARP1 actin-related protein 1 homolog B, centractin beta (yeast) |
| ALPK1 | alpha-kinase 1 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANO10 | anoctamin 10 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BTBD2 | BTB (POZ) domain containing 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHKB | choline kinase beta |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CTSD | cathepsin D |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPM3 | dolichyl-phosphate mannosyltransferase polypeptide 3 |
| EGF | epidermal growth factor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM222B | family with sequence similarity 222, member B |
| FICD | FIC domain containing |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H3B | histone cluster 1, H3b |
| HLX | H2.0-like homeobox |
| HMOX1 | heme oxygenase 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0232 | KIAA0232 |
| KLF11 | Kruppel-like factor 11 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LMBR1L | limb development membrane protein 1-like |
| LOC100127972 | uncharacterized LOC100127972 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED22 | mediator complex subunit 22 |
| MITF | microphthalmia-associated transcription factor |
| MT1M | metallothionein 1M |
| MTMR11 | myotubularin related protein 11 |
| NAG18 | NAG18 mRNA |
| NOP2 | NOP2 nucleolar protein |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OCLN | occludin |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDZD2 | PDZ domain containing 2 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLCD1 | phospholipase C, delta 1 |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| SAMD9 | sterile alpha motif domain containing 9 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SPAG4 | sperm associated antigen 4 |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3 | stromal antigen 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STBD1 | starch binding domain 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TDRD7 | tudor domain containing 7 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TNS2 | tensin 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSPAN1 | tetraspanin 1 |
| TSPYL2 | TSPY-like 2 |
| UBXN6 | UBX domain protein 6 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF177 | zinc finger protein 177 |
| ZNF426 | zinc finger protein 426 |
| ZNF552 | zinc finger protein 552 |
| ZNF574 | zinc finger protein 574 |
| ZNF787 | zinc finger protein 787 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
