| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the meropenem-6141 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| AMPH | amphiphysin |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| BIN1 | bridging integrator 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CASC1 | cancer susceptibility candidate 1 |
| CCDC57 | coiled-coil domain containing 57 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLTA | clathrin, light chain A |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNR1 | cannabinoid receptor 1 (brain) |
| COL17A1 | collagen, type XVII, alpha 1 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| EPHA1 | EPH receptor A1 |
| F2R | coagulation factor II (thrombin) receptor |
| FBXO2 | F-box protein 2 |
| FOXD2 | forkhead box D2 |
| FOXG1 | forkhead box G1 |
| FUS | FUS RNA binding protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GHRHR | growth hormone releasing hormone receptor |
| GLRA1 | glycine receptor, alpha 1 |
| GLRB | glycine receptor, beta |
| GPATCH4 | G patch domain containing 4 |
| GPR132 | G protein-coupled receptor 132 |
| GTPBP1 | GTP binding protein 1 |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HTR7 | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
| IDS | iduronate 2-sulfatase |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KIAA1462 | KIAA1462 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KRT8 | keratin 8, type II |
| KYNU | kynureninase |
| L1TD1 | LINE-1 type transposase domain containing 1 |
| LMTK2 | lemur tyrosine kinase 2 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| MMP3 | matrix metallopeptidase 3 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTMR3 | myotubularin related protein 3 |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NEUROD1 | neuronal differentiation 1 |
| NF2 | neurofibromin 2 (merlin) |
| NPFF | neuropeptide FF-amide peptide precursor |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NXPH4 | neurexophilin 4 |
| ONECUT2 | one cut homeobox 2 |
| OSBPL7 | oxysterol binding protein-like 7 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDLIM4 | PDZ and LIM domain 4 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PPEF1 | protein phosphatase, EF-hand calcium binding domain 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRSS53 | protease, serine, 53 |
| RERGL | RERG/RAS-like |
| RHBDD3 | rhomboid domain containing 3 |
| RIF1 | replication timing regulatory factor 1 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLAMF7 | SLAM family member 7 |
| SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPRR2B | small proline-rich protein 2B |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| ST7L | suppression of tumorigenicity 7 like |
| STMN4 | stathmin-like 4 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCL1A | T-cell leukemia/lymphoma 1A |
| TEF | thyrotrophic embryonic factor |
| TM4SF4 | transmembrane 4 L six family member 4 |
| TMC7 | transmembrane channel-like 7 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPMT | thiopurine S-methyltransferase |
| TRPC2 | transient receptor potential cation channel, subfamily C, member 2, pseudogene |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| XIST | X inactive specific transcript (non-protein coding) |
| XYLB | xylulokinase homolog (H. influenzae) |
| YLPM1 | YLP motif containing 1 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ARRB1 | arrestin, beta 1 |
| BAG3 | BCL2-associated athanogene 3 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CCDC9 | coiled-coil domain containing 9 |
| CD82 | CD82 molecule |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHMP7 | charged multivesicular body protein 7 |
| CKB | creatine kinase, brain |
| COG4 | component of oligomeric golgi complex 4 |
| COL15A1 | collagen, type XV, alpha 1 |
| CORO7 | coronin 7 |
| CTSO | cathepsin O |
| CUX2 | cut-like homeobox 2 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM188A | family with sequence similarity 188, member A |
| FCF1 | FCF1 rRNA-processing protein |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FJX1 | four jointed box 1 (Drosophila) |
| GK3P | glycerol kinase 3 pseudogene |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GPALPP1 | GPALPP motifs containing 1 |
| GPATCH3 | G patch domain containing 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2BN | histone cluster 1, H2bn |
| HP | haptoglobin |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| KIAA0753 | KIAA0753 |
| KIF3C | kinesin family member 3C |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MDM4 | MDM4, p53 regulator |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDGFD | platelet derived growth factor D |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMP22 | peripheral myelin protein 22 |
| POLL | polymerase (DNA directed), lambda |
| POLM | polymerase (DNA directed), mu |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| PYGB | phosphorylase, glycogen; brain |
| RGS13 | regulator of G-protein signaling 13 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| RHOH | ras homolog family member H |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIGLEC9 | sialic acid binding Ig-like lectin 9 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SPATS2 | spermatogenesis associated, serine-rich 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| THAP10 | THAP domain containing 10 |
| TMEM242 | transmembrane protein 242 |
| TRIM36 | tripartite motif containing 36 |
| TSPAN32 | tetraspanin 32 |
| TSPYL2 | TSPY-like 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| UPK3A | uroplakin 3A |
| UPP1 | uridine phosphorylase 1 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR76 | WD repeat domain 76 |
| WDR91 | WD repeat domain 91 |
| WWC3 | WWC family member 3 |
| YY2 | YY2 transcription factor |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP37 | ZFP37 zinc finger protein |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF35 | zinc finger protein 35 |
| ZNF862 | zinc finger protein 862 |
