| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the meropenem-7180 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACO2 | aconitase 2, mitochondrial |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APC | adenomatous polyposis coli |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| AVL9 | AVL9 homolog (S. cerevisiase) |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCNO | cyclin O |
| CDC14A | cell division cycle 14A |
| CEMP1 | cementum protein 1 |
| CEP164 | centrosomal protein 164kDa |
| CHKB | choline kinase beta |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COMT | catechol-O-methyltransferase |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPD | carboxypeptidase D |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| DAPK3 | death-associated protein kinase 3 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DOK4 | docking protein 4 |
| EGFR | epidermal growth factor receptor |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FBXO40 | F-box protein 40 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| FZD1 | frizzled class receptor 1 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HFE | hemochromatosis |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HMOX1 | heme oxygenase 1 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT140 | intraflagellar transport 140 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITGA10 | integrin, alpha 10 |
| ITGA6 | integrin, alpha 6 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MECOM | MDS1 and EVI1 complex locus |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MTSS1L | metastasis suppressor 1-like |
| MXD4 | MAX dimerization protein 4 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKTR | natural killer cell triggering receptor |
| NOP14-AS1 | NOP14 antisense RNA 1 |
| OGFOD2 | 2-oxoglutarate and iron-dependent oxygenase domain containing 2 |
| OSMR | oncostatin M receptor |
| PARD6B | par-6 family cell polarity regulator beta |
| PCM1 | pericentriolar material 1 |
| PLK4 | polo-like kinase 4 |
| PLXNC1 | plexin C1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PSPH | phosphoserine phosphatase |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RBM5 | RNA binding motif protein 5 |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| RFXAP | regulatory factor X-associated protein |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| SFXN3 | sideroflexin 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SKIL | SKI-like proto-oncogene |
| SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SRI | sorcin |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAPBP | TAP binding protein (tapasin) |
| TAZ | tafazzin |
| TJP3 | tight junction protein 3 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS2 | transmembrane protease, serine 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TXNIP | thioredoxin interacting protein |
| TXNL4A | thioredoxin-like 4A |
| VEZT | vezatin, adherens junctions transmembrane protein |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALPK1 | alpha-kinase 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BCORL1 | BCL6 corepressor-like 1 |
| BSDC1 | BSD domain containing 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C14ORF132 | chromosome 14 open reading frame 132 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CBX4 | chromobox homolog 4 |
| CCDC88C | coiled-coil domain containing 88C |
| CCDC92 | coiled-coil domain containing 92 |
| CCNT1 | cyclin T1 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CKB | creatine kinase, brain |
| CLASRP | CLK4-associating serine/arginine rich protein |
| COL9A2 | collagen, type IX, alpha 2 |
| COPS7B | COP9 signalosome subunit 7B |
| CXORF56 | chromosome X open reading frame 56 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DSPP | dentin sialophosphoprotein |
| EVPL | envoplakin |
| FAM114A1 | family with sequence similarity 114, member A1 |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FOXC1 | forkhead box C1 |
| GRAMD4 | GRAM domain containing 4 |
| GTPBP6 | GTP binding protein 6 (putative) |
| HIST1H2AI | histone cluster 1, H2ai |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IPO8 | importin 8 |
| IRF7 | interferon regulatory factor 7 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0922 | KIAA0922 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LOXL1 | lysyl oxidase-like 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MAP6D1 | MAP6 domain containing 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MED15 | mediator complex subunit 15 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MXD3 | MAX dimerization protein 3 |
| NEO1 | neogenin 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PCDHB3 | protocadherin beta 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLD3 | phospholipase D family, member 3 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF170 | ring finger protein 170 |
| RNF25 | ring finger protein 25 |
| SAMHD1 | SAM domain and HD domain 1 |
| SECISBP2L | SECIS binding protein 2-like |
| SH2D4A | SH2 domain containing 4A |
| SHPK | sedoheptulokinase |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SNX16 | sorting nexin 16 |
| STAG3 | stromal antigen 3 |
| TBX19 | T-box 19 |
| TMEM110 | transmembrane protein 110 |
| TMEM132A | transmembrane protein 132A |
| TRAIP | TRAF interacting protein |
| TSPAN14 | tetraspanin 14 |
| TUBA3C | tubulin, alpha 3c |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UBXN6 | UBX domain protein 6 |
| VWA1 | von Willebrand factor A domain containing 1 |
| YEATS2 | YEATS domain containing 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF254 | zinc finger protein 254 |
| ZNF552 | zinc finger protein 552 |
| ZNF813 | zinc finger protein 813 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |