| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the mesalazine-5888 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADAM28 | ADAM metallopeptidase domain 28 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANKRD7 | ankyrin repeat domain 7 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ARTN | artemin |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| C8A | complement component 8, alpha polypeptide |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CDY1 | chromodomain protein, Y-linked, 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLDN17 | claudin 17 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRP | C-reactive protein, pentraxin-related |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DST | dystonin |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELL | elongation factor RNA polymerase II |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| ESRRG | estrogen-related receptor gamma |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FMO4 | flavin containing monooxygenase 4 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLP1R | glucagon-like peptide 1 receptor |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| GPR50 | G protein-coupled receptor 50 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HSPB3 | heat shock 27kDa protein 3 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL11 | interleukin 11 |
| JUND | jun D proto-oncogene |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KRT83 | keratin 83, type II |
| KYNU | kynureninase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC75B | leucine rich repeat containing 75B |
| MAGEA5 | melanoma antigen family A5 |
| MAGEB2 | melanoma antigen family B2 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MAPT | microtubule-associated protein tau |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MUC1 | mucin 1, cell surface associated |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| MYF5 | myogenic factor 5 |
| MYO7A | myosin VIIA |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDZK1 | PDZ domain containing 1 |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| POU4F1 | POU class 4 homeobox 1 |
| PRR7 | proline rich 7 (synaptic) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PURA | purine-rich element binding protein A |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAD54B | RAD54 homolog B (S. cerevisiae) |
| RANGAP1 | Ran GTPase activating protein 1 |
| RIMBP2 | RIMS binding protein 2 |
| RTN2 | reticulon 2 |
| SFTPB | surfactant protein B |
| SIAH1 | siah E3 ubiquitin protein ligase 1 |
| SLAMF8 | SLAM family member 8 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAGLN | transgelin |
| TBC1D22A | TBC1 domain family, member 22A |
| TESC | tescalcin |
| TLE4 | transducin-like enhancer of split 4 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TPR | translocated promoter region, nuclear basket protein |
| TTC9 | tetratricopeptide repeat domain 9 |
| TTF1 | transcription termination factor, RNA polymerase I |
| UBXN1 | UBX domain protein 1 |
| VWA5A | von Willebrand factor A domain containing 5A |
| YIPF4 | Yip1 domain family, member 4 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF484 | zinc finger protein 484 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| AMT | aminomethyltransferase |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOL6 | apolipoprotein L, 6 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| BOLA1 | bolA family member 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5 | complement component 5 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN5 | calpain 5 |
| CARD8 | caspase recruitment domain family, member 8 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CPVL | carboxypeptidase, vitellogenic-like |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRBN | cereblon |
| CUL9 | cullin 9 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| EFNA3 | ephrin-A3 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| FBRS | fibrosin |
| FPGS | folylpolyglutamate synthase |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR176 | G protein-coupled receptor 176 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3C | histone cluster 1, H3c |
| HIST1H3G | histone cluster 1, H3g |
| HOMER2 | homer scaffolding protein 2 |
| IFI30 | interferon, gamma-inducible protein 30 |
| ILK | integrin-linked kinase |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0513 | KIAA0513 |
| KLHL28 | kelch-like family member 28 |
| KRT31 | keratin 31, type I |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYLK | myosin light chain kinase |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRSN2 | neurensin 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRAME | preferentially expressed antigen in melanoma |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRR14L | proline rich 14-like |
| PRSS16 | protease, serine, 16 (thymus) |
| PRSS22 | protease, serine, 22 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| REEP4 | receptor accessory protein 4 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RGCC | regulator of cell cycle |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL10L | ribosomal protein L10-like |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAGLN3 | transgelin 3 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIM21 | tripartite motif containing 21 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA3C | tubulin, alpha 3c |
| TULP4 | tubby like protein 4 |
| TXLNG | taxilin gamma |
| TYK2 | tyrosine kinase 2 |
| WBP2 | WW domain binding protein 2 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF253 | zinc finger protein 253 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
