mesenchymal cell differentiation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. (Gene Ontology, GO_0048762)
External Link http://amigo.geneontology.org/amigo/term/GO:0048762
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Genes

59 genes participating in the mesenchymal cell differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
AKNA AT-hook transcription factor
AMELX amelogenin, X-linked
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL7 cullin 7
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DLG5 discs, large homolog 5 (Drosophila)
FBXL17 F-box and leucine-rich repeat protein 17
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FOXC1 forkhead box C1
FOXF2 forkhead box F2
GSK3B glycogen synthase kinase 3 beta
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
ISL1 ISL LIM homeobox 1
LEF1 lymphoid enhancer-binding factor 1
LIMS1 LIM and senescent cell antigen-like domains 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LRP6 low density lipoprotein receptor-related protein 6
MEF2C myocyte enhancer factor 2C
NCAM1 neural cell adhesion molecule 1
NOG noggin
NOTCH1 notch 1
NOTCH4 notch 4
OTUD5 OTU deubiquitinase 5
RANBP3L RAN binding protein 3-like
RBPJ recombination signal binding protein for immunoglobulin kappa J region
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
S100A4 S100 calcium binding protein A4
SACK1D scaffolding CK1 anchoring protein D
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC39A10 solute carrier family 39 (zinc transporter), member 10
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SMAD4 SMAD family member 4
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOS1 son of sevenless homolog 1 (Drosophila)
SOX9 SRY (sex determining region Y)-box 9
TBX20 T-box 20
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TGFBR3L transforming growth factor, beta receptor III-like
TRIM28 tripartite motif containing 28
WNT4 wingless-type MMTV integration site family, member 4
WNT5A wingless-type MMTV integration site family, member 5A
ZFP64 ZFP64 zinc finger protein