mestranol-3008 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the mestranol-3008 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACTC1 actin, alpha, cardiac muscle 1
ALDOB aldolase B, fructose-bisphosphate
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APOE apolipoprotein E
AQP7 aquaporin 7
ASCL1 achaete-scute family bHLH transcription factor 1
ASTN1 astrotactin 1
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
B9D2 B9 protein domain 2
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BDNF brain-derived neurotrophic factor
BGN biglycan
BPI bactericidal/permeability-increasing protein
C9ORF9 chromosome 9 open reading frame 9
CALD1 caldesmon 1
CD247 CD247 molecule
CD300C CD300c molecule
CEP131 centrosomal protein 131kDa
CHMP6 charged multivesicular body protein 6
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COL13A1 collagen, type XIII, alpha 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DOCK5 dedicator of cytokinesis 5
DSCR4 Down syndrome critical region 4
DUSP4 dual specificity phosphatase 4
EFNB3 ephrin-B3
EGR3 early growth response 3
EML2 echinoderm microtubule associated protein like 2
FAM127B family with sequence similarity 127, member B
FBLN1 fibulin 1
FDPS farnesyl diphosphate synthase
FST follistatin
FZD3 frizzled class receptor 3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GIF gastric intrinsic factor (vitamin B synthesis)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
IGLV1-44 immunoglobulin lambda variable 1-44
INF2 inverted formin, FH2 and WH2 domain containing
LCMT2 leucine carboxyl methyltransferase 2
LIMD2 LIM domain containing 2
MED14 mediator complex subunit 14
MLANA melan-A
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MORC1 MORC family CW-type zinc finger 1
MPZL1 myelin protein zero-like 1
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYLK myosin light chain kinase
NEBL nebulette
NFE2L3 nuclear factor, erythroid 2-like 3
NMT1 N-myristoyltransferase 1
NMT2 N-myristoyltransferase 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTN1 netrin 1
OGFR opioid growth factor receptor
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PCGF2 polycomb group ring finger 2
PDE4DIP phosphodiesterase 4D interacting protein
PHF20L1 PHD finger protein 20-like 1
PLCL2 phospholipase C-like 2
POLM polymerase (DNA directed), mu
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PTPRD protein tyrosine phosphatase, receptor type, D
RASAL2 RAS protein activator like 2
RB1 retinoblastoma 1
RHEB Ras homolog enriched in brain
RIPPLY3 ripply transcriptional repressor 3
RNF39 ring finger protein 39
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SH3BP1 SH3-domain binding protein 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A8 solute carrier family 12, member 8
SLC12A9 solute carrier family 12, member 9
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SNAI1 snail family zinc finger 1
SSPN sarcospan
STS steroid sulfatase (microsomal), isozyme S
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TBX5 T-box 5
TLN2 talin 2
TMEM51 transmembrane protein 51
TNP2 transition protein 2 (during histone to protamine replacement)
TP73-AS1 TP73 antisense RNA 1
TRAT1 T cell receptor associated transmembrane adaptor 1
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
TUBA4B tubulin, alpha 4b
VAMP5 vesicle-associated membrane protein 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ADGB androglobin
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARID5A AT rich interactive domain 5A (MRF1-like)
ARMCX4 armadillo repeat containing, X-linked 4
ASB7 ankyrin repeat and SOCS box containing 7
BAHD1 bromo adjacent homology domain containing 1
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C22ORF46 chromosome 22 open reading frame 46
C5AR1 complement component 5a receptor 1
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC106 coiled-coil domain containing 106
CD3D CD3d molecule, delta (CD3-TCR complex)
CDR2L cerebellar degeneration-related protein 2-like
CHM choroideremia (Rab escort protein 1)
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CORT cortistatin
CPTP ceramide-1-phosphate transfer protein
CROT carnitine O-octanoyltransferase
CYSLTR1 cysteinyl leukotriene receptor 1
DENND5B DENN/MADD domain containing 5B
DEPDC5 DEP domain containing 5
DHRS11 dehydrogenase/reductase (SDR family) member 11
DSPP dentin sialophosphoprotein
EBF2 early B-cell factor 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM204A family with sequence similarity 204, member A
FBXL2 F-box and leucine-rich repeat protein 2
FGF23 fibroblast growth factor 23
FRMPD1 FERM and PDZ domain containing 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPC3 glypican 3
GPR1 G protein-coupled receptor 1
GSTA4 glutathione S-transferase alpha 4
GSTZ1 glutathione S-transferase zeta 1
HAMP hepcidin antimicrobial peptide
HDAC7 histone deacetylase 7
HIST1H1D histone cluster 1, H1d
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXB9 homeobox B9
HPR haptoglobin-related protein
IFNA14 interferon, alpha 14
IGH immunoglobulin heavy locus
KDM8 lysine (K)-specific demethylase 8
KIAA0753 KIAA0753
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIME1 Lck interacting transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
LOC157562 uncharacterized LOC157562
LPPR3 lipid phosphate phosphatase-related protein type 3
MAGEF1 melanoma antigen family F1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MUC6 mucin 6, oligomeric mucus/gel-forming
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAG18 NAG18 mRNA
NINJ2 ninjurin 2
NLGN1 neuroligin 1
NMUR1 neuromedin U receptor 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PBOV1 prostate and breast cancer overexpressed 1
PCBP4 poly(rC) binding protein 4
PCDH12 protocadherin 12
PIPOX pipecolic acid oxidase
PPIEL peptidylprolyl isomerase E-like pseudogene
PRB3 proline-rich protein BstNI subfamily 3
PRO2964 uncharacterized protein PRO2964
PRSS53 protease, serine, 53
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGS13 regulator of G-protein signaling 13
SCAI suppressor of cancer cell invasion
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIX3 SIX homeobox 3
SLC16A4 solute carrier family 16, member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPATA2L spermatogenesis associated 2-like
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAS2R10 taste receptor, type 2, member 10
TBX19 T-box 19
THBS4 thrombospondin 4
TMEM120B transmembrane protein 120B
TMEM140 transmembrane protein 140
TMEM212 transmembrane protein 212
TNNT1 troponin T type 1 (skeletal, slow)
TOLLIP toll interacting protein
TOR4A torsin family 4, member A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
VEGFC vascular endothelial growth factor C
ZNF385D zinc finger protein 385D