| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the mestranol-4792 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| ALDOB | aldolase B, fructose-bisphosphate |
| ATM | ATM serine/threonine kinase |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEMP1 | cementum protein 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CTSZ | cathepsin Z |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSCAM | Down syndrome cell adhesion molecule |
| DST | dystonin |
| EFNA3 | ephrin-A3 |
| EGF | epidermal growth factor |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EMID1 | EMI domain containing 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHA1 | EPH receptor A1 |
| EPOR | erythropoietin receptor |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ESR2 | estrogen receptor 2 (ER beta) |
| FGF18 | fibroblast growth factor 18 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FYB | FYN binding protein |
| GLRA1 | glycine receptor, alpha 1 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HFE | hemochromatosis |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IFT27 | intraflagellar transport 27 |
| IFT38 | intraflagellar transport 38 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| JUN | jun proto-oncogene |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KIF5A | kinesin family member 5A |
| KSR1 | kinase suppressor of ras 1 |
| LEFTY1 | left-right determination factor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MCAM | melanoma cell adhesion molecule |
| MCOLN3 | mucolipin 3 |
| MED25 | mediator complex subunit 25 |
| MGC2889 | uncharacterized protein MGC2889 |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NMBR | neuromedin B receptor |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OGFR | opioid growth factor receptor |
| PHF1 | PHD finger protein 1 |
| PLAUR | plasminogen activator, urokinase receptor |
| POLL | polymerase (DNA directed), lambda |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAD51B | RAD51 paralog B |
| RUNX1 | runt-related transcription factor 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SFTPB | surfactant protein B |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBXA2R | thromboxane A2 receptor |
| TFEB | transcription factor EB |
| THBS3 | thrombospondin 3 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TRIM2 | tripartite motif containing 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| UBOX5 | U-box domain containing 5 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR78 | WD repeat domain 78 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF222 | zinc finger protein 222 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASD1 | CAS1 domain containing 1 |
| CCDC88C | coiled-coil domain containing 88C |
| CENPC | centromere protein C |
| CENPQ | centromere protein Q |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 |
| CLDN15 | claudin 15 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COCH | cochlin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| DCTN4 | dynactin 4 (p62) |
| DEAF1 | DEAF1 transcription factor |
| DOCK1 | dedicator of cytokinesis 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| FAIM | Fas apoptotic inhibitory molecule |
| FAM46C | family with sequence similarity 46, member C |
| FBXO22 | F-box protein 22 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATA6 | GATA binding protein 6 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GHR | growth hormone receptor |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HRSP12 | heat-responsive protein 12 |
| ICK | intestinal cell (MAK-like) kinase |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL17RA | interleukin 17 receptor A |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| IREB2 | iron-responsive element binding protein 2 |
| IRF6 | interferon regulatory factor 6 |
| KIAA0430 | KIAA0430 |
| KLHL2 | kelch-like family member 2 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LOC730101 | uncharacterized LOC730101 |
| MAGEF1 | melanoma antigen family F1 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MEX3C | mex-3 RNA binding family member C |
| MGC12488 | |
| MINPP1 | multiple inositol-polyphosphate phosphatase 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NEK11 | NIMA-related kinase 11 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OTUD3 | OTU deubiquitinase 3 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PPCS | phosphopantothenoylcysteine synthetase |
| PPWD1 | peptidylprolyl isomerase domain and WD repeat containing 1 |
| PRPF39 | pre-mRNA processing factor 39 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RANBP17 | RAN binding protein 17 |
| RGS17 | regulator of G-protein signaling 17 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC24B | SEC24 family member B |
| SH2B3 | SH2B adaptor protein 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAI2 | snail family zinc finger 2 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TGDS | TDP-glucose 4,6-dehydratase |
| TMEM230 | transmembrane protein 230 |
| TMEM53 | transmembrane protein 53 |
| TNS3 | tensin 3 |
| TP53BP2 | tumor protein p53 binding protein 2 |
| TRIM25 | tripartite motif containing 25 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| ZIC1 | Zic family member 1 |
| ZNF107 | zinc finger protein 107 |
| ZNF143 | zinc finger protein 143 |
| ZNF184 | zinc finger protein 184 |
| ZNF324 | zinc finger protein 324 |
| ZNF492 | zinc finger protein 492 |
| ZNF571 | zinc finger protein 571 |
| ZNF623 | zinc finger protein 623 |
