| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the metacycline-2901 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ADORA1 | adenosine A1 receptor |
| AFF2 | AF4/FMR2 family, member 2 |
| AGFG1 | ArfGAP with FG repeats 1 |
| AIM1L | absent in melanoma 1-like |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| APOE | apolipoprotein E |
| AREG | amphiregulin |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP10B | ATPase, class V, type 10B |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BSPRY | B-box and SPRY domain containing |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CDH8 | cadherin 8, type 2 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLTA | clathrin, light chain A |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CRYGC | crystallin, gamma C |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYB561 | cytochrome b561 |
| CYHR1 | cysteine/histidine-rich 1 |
| DICER1 | dicer 1, ribonuclease type III |
| EFNA4 | ephrin-A4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGFR | epidermal growth factor receptor |
| EMID1 | EMI domain containing 1 |
| EXPH5 | exophilin 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPR153 | G protein-coupled receptor 153 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GYPB | glycophorin B (MNS blood group) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXB9 | homeobox B9 |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| IL11 | interleukin 11 |
| IL27RA | interleukin 27 receptor, alpha |
| INA | internexin neuronal intermediate filament protein, alpha |
| IQCE | IQ motif containing E |
| IRF5 | interferon regulatory factor 5 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIF16B | kinesin family member 16B |
| KLHL28 | kelch-like family member 28 |
| KLHL3 | kelch-like family member 3 |
| KRTAP5-8 | keratin associated protein 5-8 |
| LAMB3 | laminin, beta 3 |
| LATS1 | large tumor suppressor kinase 1 |
| LMF1 | lipase maturation factor 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MYL10 | myosin, light chain 10, regulatory |
| MYO9B | myosin IXB |
| NANOG | Nanog homeobox |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| OGFR | opioid growth factor receptor |
| PML | promyelocytic leukemia |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RAP1GAP | RAP1 GTPase activating protein |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RGS10 | regulator of G-protein signaling 10 |
| RGS5 | regulator of G-protein signaling 5 |
| RPL7 | ribosomal protein L7 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A13 | S100 calcium binding protein A13 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SFTPB | surfactant protein B |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC28A3 | solute carrier family 28 (concentrative nucleoside transporter), member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPHK1 | sphingosine kinase 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TLN2 | talin 2 |
| TMEM176A | transmembrane protein 176A |
| TMEM63A | transmembrane protein 63A |
| TOP3B | topoisomerase (DNA) III beta |
| TRAF4 | TNF receptor-associated factor 4 |
| TTC38 | tetratricopeptide repeat domain 38 |
| USP53 | ubiquitin specific peptidase 53 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ABHD4 | abhydrolase domain containing 4 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BPI | bactericidal/permeability-increasing protein |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBX7 | chromobox homolog 7 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD300C | CD300c molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CHMP7 | charged multivesicular body protein 7 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| DENND4C | DENN/MADD domain containing 4C |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMBP | dynamin binding protein |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific |
| EGR2 | early growth response 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM188A | family with sequence similarity 188, member A |
| FAM53B | family with sequence similarity 53, member B |
| FES | FES proto-oncogene, tyrosine kinase |
| GID4 | GID complex subunit 4 |
| GSTZ1 | glutathione S-transferase zeta 1 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H4D | histone cluster 1, H4d |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXA5 | homeobox A5 |
| HP | haptoglobin |
| HPSE | heparanase |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IQCG | IQ motif containing G |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGA10 | integrin, alpha 10 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| LOC729164 | hCG1732469 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MYH15 | myosin, heavy chain 15 |
| NABP2 | nucleic acid binding protein 2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NOL10 | nucleolar protein 10 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDGFD | platelet derived growth factor D |
| PIR | pirin (iron-binding nuclear protein) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| POR | P450 (cytochrome) oxidoreductase |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PYGB | phosphorylase, glycogen; brain |
| RAB23 | RAB23, member RAS oncogene family |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SEC31B | SEC31 homolog B (S. cerevisiae) |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STK11 | serine/threonine kinase 11 |
| STX1A | syntaxin 1A (brain) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TBC1D17 | TBC1 domain family, member 17 |
| TESK1 | testis-specific kinase 1 |
| THBS3 | thrombospondin 3 |
| THEM6 | thioesterase superfamily member 6 |
| TKFC | triokinase/FMN cyclase |
| TPCN1 | two pore segment channel 1 |
| TRABD | TraB domain containing |
| TRIM5 | tripartite motif containing 5 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA3C | tubulin, alpha 3c |
| ZNF428 | zinc finger protein 428 |
| ZNF816 | zinc finger protein 816 |
