| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metacycline-4143 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| AHSP | alpha hemoglobin stabilizing protein |
| AQP6 | aquaporin 6, kidney specific |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| CARTPT | CART prepropeptide |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CDK2 | cyclin-dependent kinase 2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLCA2 | chloride channel accessory 2 |
| CLDN17 | claudin 17 |
| COL10A1 | collagen, type X, alpha 1 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| COL7A1 | collagen, type VII, alpha 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYP4A22 | cytochrome P450, family 4, subfamily A, polypeptide 22 |
| DENND6B | DENN/MADD domain containing 6B |
| DKFZP434L187 | uncharacterized LOC26082 |
| DMPK | dystrophia myotonica-protein kinase |
| DVL2 | dishevelled segment polarity protein 2 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| FAM134B | family with sequence similarity 134, member B |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF14 | fibroblast growth factor 14 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
| FOXE1 | forkhead box E1 |
| GABRB1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GFER | growth factor, augmenter of liver regeneration |
| GFI1B | growth factor independent 1B transcription repressor |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A |
| GRK5 | G protein-coupled receptor kinase 5 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| IFNA10 | interferon, alpha 10 |
| IFNA5 | interferon, alpha 5 |
| IMPG1 | interphotoreceptor matrix proteoglycan 1 |
| INSL3 | insulin-like 3 (Leydig cell) |
| IRF8 | interferon regulatory factor 8 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLF13 | Kruppel-like factor 13 |
| KRT23 | keratin 23, type I |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| MAGEA8 | melanoma antigen family A8 |
| MCAM | melanoma cell adhesion molecule |
| MECOM | MDS1 and EVI1 complex locus |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MTSS1 | metastasis suppressor 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NLRP3 | NLR family, pyrin domain containing 3 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| OR2W1 | olfactory receptor, family 2, subfamily W, member 1 |
| PAH | phenylalanine hydroxylase |
| PDLIM4 | PDZ and LIM domain 4 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PPP1R17 | protein phosphatase 1, regulatory subunit 17 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| RAB40C | RAB40C, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RORA | RAR-related orphan receptor A |
| SATB2 | SATB homeobox 2 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SH2D3A | SH2 domain containing 3A |
| SIPA1 | signal-induced proliferation-associated 1 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SYN2 | synapsin II |
| TDRD12 | tudor domain containing 12 |
| TEX13A | testis expressed 13A |
| TRIM29 | tripartite motif containing 29 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC22 | tetratricopeptide repeat domain 22 |
| TULP2 | tubby like protein 2 |
| UPK1A | uroplakin 1A |
| USP22 | ubiquitin specific peptidase 22 |
| WNT2B | wingless-type MMTV integration site family, member 2B |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF44 | zinc finger protein 44 |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACTL8 | actin-like 8 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CES3 | carboxylesterase 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHKB | choline kinase beta |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUEDC1 | CUE domain containing 1 |
| DBF4B | DBF4 zinc finger B |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM46C | family with sequence similarity 46, member C |
| FBXO2 | F-box protein 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GFI1 | growth factor independent 1 transcription repressor |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HDAC11 | histone deacetylase 11 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOXB2 | homeobox B2 |
| HPN | hepsin |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL28 | kelch-like family member 28 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRRC20 | leucine rich repeat containing 20 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAP7D1 | MAP7 domain containing 1 |
| MEFV | Mediterranean fever |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MOB3B | MOB kinase activator 3B |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTCP1 | mature T-cell proliferation 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| NBEAL2 | neurobeachin-like 2 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKX3-2 | NK3 homeobox 2 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OLFML2A | olfactomedin-like 2A |
| PARPBP | PARP1 binding protein |
| PCDHB13 | protocadherin beta 13 |
| PCDHB3 | protocadherin beta 3 |
| PCDHB8 | protocadherin beta 8 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLA2G3 | phospholipase A2, group III |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKCE | protein kinase C, epsilon |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TMEM121 | transmembrane protein 121 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TSPAN1 | tetraspanin 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
| ZNF787 | zinc finger protein 787 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
