| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
196 genes differentially expressed following the metacycline-7321 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC181 | coiled-coil domain containing 181 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| DAGLA | diacylglycerol lipase, alpha |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DVL2 | dishevelled segment polarity protein 2 |
| EPHB2 | EPH receptor B2 |
| EXOSC1 | exosome component 1 |
| FAM174B | family with sequence similarity 174, member B |
| FAM212B | family with sequence similarity 212, member B |
| FAM63B | family with sequence similarity 63, member B |
| FBXO41 | F-box protein 41 |
| FECH | ferrochelatase |
| FER | fer (fps/fes related) tyrosine kinase |
| FRK | fyn-related Src family tyrosine kinase |
| FZD7 | frizzled class receptor 7 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| HAMP | hepcidin antimicrobial peptide |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HIC2 | hypermethylated in cancer 2 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IKBKAP | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein |
| IQCG | IQ motif containing G |
| ITGB4 | integrin, beta 4 |
| ITM2C | integral membrane protein 2C |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KITLG | KIT ligand |
| KLK3 | kallikrein-related peptidase 3 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT37 | keratin 37, type I |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOC644450 | uncharacterized LOC644450 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K |
| MAGEA3 | melanoma antigen family A3 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MCOLN1 | mucolipin 1 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| NF1 | neurofibromin 1 |
| NME5 | NME/NM23 family member 5 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAPOLA | poly(A) polymerase alpha |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLAUR | plasminogen activator, urokinase receptor |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRLR | prolactin receptor |
| PRSS53 | protease, serine, 53 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RAB11B | RAB11B, member RAS oncogene family |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RND1 | Rho family GTPase 1 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SBF1 | SET binding factor 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TADA3 | transcriptional adaptor 3 |
| TBC1D2 | TBC1 domain family, member 2 |
| TCTN2 | tectonic family member 2 |
| TDRKH | tudor and KH domain containing |
| THBD | thrombomodulin |
| TMEM212 | transmembrane protein 212 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRD | T cell receptor delta locus |
| TRIM45 | tripartite motif containing 45 |
| TSPAN9 | tetraspanin 9 |
| TXNL4A | thioredoxin-like 4A |
| USP46 | ubiquitin specific peptidase 46 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABHD17B | abhydrolase domain containing 17B |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CAPN15 | calpain 15 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN15 | claudin 15 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EVPL | envoplakin |
| FLT4 | fms-related tyrosine kinase 4 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BF | histone cluster 1, H2bf |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KIFAP3 | kinesin-associated protein 3 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LOC730101 | uncharacterized LOC730101 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MANBA | mannosidase, beta A, lysosomal |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MCOLN3 | mucolipin 3 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| P3H1 | prolyl 3-hydroxylase 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLA2G15 | phospholipase A2, group XV |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RAB28 | RAB28, member RAS oncogene family |
| RAB4B | RAB4B, member RAS oncogene family |
| RBM38 | RNA binding motif protein 38 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF25 | ring finger protein 25 |
| RNF31 | ring finger protein 31 |
| RPAP2 | RNA polymerase II associated protein 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TARP | TCR gamma alternate reading frame protein |
| TLN1 | talin 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM183A | transmembrane protein 183A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM25 | tripartite motif containing 25 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TSPAN1 | tetraspanin 1 |
| UBQLN4 | ubiquilin 4 |
| USP36 | ubiquitin specific peptidase 36 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF141 | zinc finger protein 141 |
| ZNF205 | zinc finger protein 205 |
| ZNF675 | zinc finger protein 675 |
| ZNF770 | zinc finger protein 770 |
| ZNF778 | zinc finger protein 778 |
