metalloendopeptidase inhibitor activity Gene Set

Dataset	GO Molecular Function Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity. (Gene Ontology, GO_0008191)
External Link	http://amigo.geneontology.org/amigo/term/GO:0008191
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Genes

14 genes performing the metalloendopeptidase inhibitor activity molecular function from the curated GO Molecular Function Annotations 2023 dataset.

Symbol	Name
BST2	bone marrow stromal cell antigen 2
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)
FETUB	fetuin B
LXN	latexin
NGF	nerve growth factor (beta polypeptide)
RARRES1	retinoic acid receptor responder (tazarotene induced) 1
RECK	reversion-inducing-cysteine-rich protein with kazal motifs
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
TIMP1	TIMP metallopeptidase inhibitor 1
TIMP2	TIMP metallopeptidase inhibitor 2
TIMP3	TIMP metallopeptidase inhibitor 3
TIMP4	TIMP metallopeptidase inhibitor 4