metampicillin-2286 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the metampicillin-2286 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACAN aggrecan
ACPP acid phosphatase, prostate
ACVR1B activin A receptor, type IB
ADAM12 ADAM metallopeptidase domain 12
ADGRE3 adhesion G protein-coupled receptor E3
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AFF1 AF4/FMR2 family, member 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
APOL3 apolipoprotein L, 3
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATAT1 alpha tubulin acetyltransferase 1
BIRC7 baculoviral IAP repeat containing 7
C10ORF95 chromosome 10 open reading frame 95
C7ORF69 chromosome 7 open reading frame 69
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDK14 cyclin-dependent kinase 14
CELF2 CUGBP, Elav-like family member 2
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CRMP1 collapsin response mediator protein 1
CTNNA2 catenin (cadherin-associated protein), alpha 2
DMXL2 Dmx-like 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFNB3 ephrin-B3
ETV7 ets variant 7
FAT4 FAT atypical cadherin 4
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGF22 fibroblast growth factor 22
FRMD1 FERM domain containing 1
GAS7 growth arrest-specific 7
GHRHR growth hormone releasing hormone receptor
GSK3A glycogen synthase kinase 3 alpha
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HOXB5 homeobox B5
HSPB6 heat shock protein, alpha-crystallin-related, B6
HUS1 HUS1 checkpoint homolog (S. pombe)
IFT54 intraflagellar transport 54
IGKV3-20 immunoglobulin kappa variable 3-20
IHH indian hedgehog
INE1 inactivation escape 1 (non-protein coding)
ING4 inhibitor of growth family, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1462 KIAA1462
LECT1 leukocyte cell derived chemotaxin 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAN1A2 mannosidase, alpha, class 1A, member 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MTRF1L mitochondrial translational release factor 1-like
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NPAS3 neuronal PAS domain protein 3
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUP54 nucleoporin 54kDa
ORM1 orosomucoid 1
PADI1 peptidyl arginine deiminase, type I
PAPPA2 pappalysin 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RERE arginine-glutamic acid dipeptide (RE) repeats
RND1 Rho family GTPase 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETBP1 SET binding protein 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC39A9 solute carrier family 39, member 9
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNRK SNF related kinase
SOCS3 suppressor of cytokine signaling 3
SRGN serglycin
SRRM2 serine/arginine repetitive matrix 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNPO synaptopodin
TAS2R10 taste receptor, type 2, member 10
TBX5 T-box 5
TEP1 telomerase-associated protein 1
THRB thyroid hormone receptor, beta
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNNT2 troponin T type 2 (cardiac)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSPAN32 tetraspanin 32
UBA6 ubiquitin-like modifier activating enzyme 6
USP36 ubiquitin specific peptidase 36
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFPL1 zinc finger protein-like 1
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRE5 adhesion G protein-coupled receptor E5
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ARC activity-regulated cytoskeleton-associated protein
ARRB1 arrestin, beta 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAG4 BCL2-associated athanogene 4
BHLHE41 basic helix-loop-helix family, member e41
C14ORF93 chromosome 14 open reading frame 93
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
C9ORF9 chromosome 9 open reading frame 9
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD80 CD80 molecule
CDK18 cyclin-dependent kinase 18
CFAP45 cilia and flagella associated protein 45
CLGN calmegin
CTRL chymotrypsin-like
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DMTN dematin actin binding protein
DNALI1 dynein, axonemal, light intermediate chain 1
DOC2A double C2-like domains, alpha
DUSP9 dual specificity phosphatase 9
ELP6 elongator acetyltransferase complex subunit 6
EMCN endomucin
EML4 echinoderm microtubule associated protein like 4
EMP3 epithelial membrane protein 3
ERCC6 excision repair cross-complementation group 6
GADD45G growth arrest and DNA-damage-inducible, gamma
GBP2 guanylate binding protein 2, interferon-inducible
GMEB1 glucocorticoid modulatory element binding protein 1
GNG13 guanine nucleotide binding protein (G protein), gamma 13
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HOXC10 homeobox C10
HP1BP3 heterochromatin protein 1, binding protein 3
HYI hydroxypyruvate isomerase (putative)
ITPKB inositol-trisphosphate 3-kinase B
JPH3 junctophilin 3
KCTD17 potassium channel tetramerization domain containing 17
KIAA0319L KIAA0319-like
KIF13A kinesin family member 13A
KLHDC8A kelch domain containing 8A
LARP6 La ribonucleoprotein domain family, member 6
LIN7A lin-7 homolog A (C. elegans)
MEFV Mediterranean fever
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MICALL2 MICAL-like 2
MMP3 matrix metallopeptidase 3
MTA2 metastasis associated 1 family, member 2
MYF5 myogenic factor 5
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
NSD1 nuclear receptor binding SET domain protein 1
NXPE3 neurexophilin and PC-esterase domain family, member 3
NYNRIN NYN domain and retroviral integrase containing
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PCDHA6 protocadherin alpha 6
PDE12 phosphodiesterase 12
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PRR4 proline rich 4 (lacrimal)
QTRT1 queuine tRNA-ribosyltransferase 1
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RCAN3 RCAN family member 3
RFPL1S RFPL1 antisense RNA 1
RIN2 Ras and Rab interactor 2
RLN1 relaxin 1
RNF39 ring finger protein 39
RPH3AL rabphilin 3A-like (without C2 domains)
S100A2 S100 calcium binding protein A2
SAYSD1 SAYSVFN motif domain containing 1
SECTM1 secreted and transmembrane 1
SLPI secretory leukocyte peptidase inhibitor
SPON2 spondin 2, extracellular matrix protein
STMN3 stathmin-like 3
STRN striatin, calmodulin binding protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBC1D17 TBC1 domain family, member 17
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMLHE trimethyllysine hydroxylase, epsilon
TMPRSS4 transmembrane protease, serine 4
TRIM36 tripartite motif containing 36
TSGA10 testis specific, 10
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VPS9D1 VPS9 domain containing 1
WASF2 WAS protein family, member 2
ZNF428 zinc finger protein 428
ZNF516 zinc finger protein 516
ZNF862 zinc finger protein 862