metampicillin-5115 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the metampicillin-5115 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
APC adenomatous polyposis coli
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ARHGAP44 Rho GTPase activating protein 44
ARID4B AT rich interactive domain 4B (RBP1-like)
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
C17ORF53 chromosome 17 open reading frame 53
C3ORF18 chromosome 3 open reading frame 18
CA1 carbonic anhydrase I
CADM4 cell adhesion molecule 4
CDRT1 CMT1A duplicated region transcript 1
CLTB clathrin, light chain B
COL6A1 collagen, type VI, alpha 1
DAPK2 death-associated protein kinase 2
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DGCR2 DiGeorge syndrome critical region gene 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DTX2 deltex 2, E3 ubiquitin ligase
EPHA1 EPH receptor A1
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
F5 coagulation factor V (proaccelerin, labile factor)
FAM102A family with sequence similarity 102, member A
FAM134B family with sequence similarity 134, member B
FAM174B family with sequence similarity 174, member B
FAM63B family with sequence similarity 63, member B
GAS7 growth arrest-specific 7
HCRP1 hepatocellular carcinoma-related HCRP1
HEXA hexosaminidase A (alpha polypeptide)
HHAT hedgehog acyltransferase
HNF1B HNF1 homeobox B
HOMER3 homer scaffolding protein 3
HS1BP3 HCLS1 binding protein 3
ICK intestinal cell (MAK-like) kinase
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCTD13 potassium channel tetramerization domain containing 13
KDM5A lysine (K)-specific demethylase 5A
KLHL22 kelch-like family member 22
LDLRAD4 low density lipoprotein receptor class A domain containing 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MASP2 mannan-binding lectin serine peptidase 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MIIP migration and invasion inhibitory protein
MYO1F myosin IF
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NEK11 NIMA-related kinase 11
NFX1 nuclear transcription factor, X-box binding 1
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPIPB3 nuclear pore complex interacting protein family, member B3
OLFML2A olfactomedin-like 2A
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PITX1 paired-like homeodomain 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLVAP plasmalemma vesicle associated protein
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG11 pregnancy specific beta-1-glycoprotein 11
RAD52 RAD52 homolog (S. cerevisiae)
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS12 regulator of G-protein signaling 12
RGS5 regulator of G-protein signaling 5
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RTEL1 regulator of telomere elongation helicase 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAP30 Sin3A-associated protein, 30kDa
SFXN3 sideroflexin 3
SHOX2 short stature homeobox 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SNCG synuclein, gamma (breast cancer-specific protein 1)
SORBS1 sorbin and SH3 domain containing 1
SORT1 sortilin 1
STOML1 stomatin (EPB72)-like 1
TJAP1 tight junction associated protein 1 (peripheral)
TMCC1 transmembrane and coiled-coil domain family 1
TMEM231 transmembrane protein 231
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TTC30A tetratricopeptide repeat domain 30A
UHRF1BP1L UHRF1 binding protein 1-like
USP34 ubiquitin specific peptidase 34
WAS Wiskott-Aldrich syndrome
XYLB xylulokinase homolog (H. influenzae)
YIPF4 Yip1 domain family, member 4
ZBTB43 zinc finger and BTB domain containing 43
ZNF407 zinc finger protein 407
ZNF492 zinc finger protein 492
ZNF528 zinc finger protein 528
ZNF550 zinc finger protein 550

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ART1 ADP-ribosyltransferase 1
ASAP1-IT1 ASAP1 intronic transcript 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD5 ATPase family, AAA domain containing 5
BEND5 BEN domain containing 5
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF21 chromosome 1 open reading frame 21
C22ORF29 chromosome 22 open reading frame 29
C7ORF69 chromosome 7 open reading frame 69
CAPN15 calpain 15
CARD8 caspase recruitment domain family, member 8
CCDC85C coiled-coil domain containing 85C
CENPO centromere protein O
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CORT cortistatin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CUZD1 CUB and zona pellucida-like domains 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGF epidermal growth factor
EXD3 exonuclease 3'-5' domain containing 3
FBXO2 F-box protein 2
FCF1 FCF1 rRNA-processing protein
FIG4 FIG4 phosphoinositide 5-phosphatase
FRMD8 FERM domain containing 8
GALT galactose-1-phosphate uridylyltransferase
GAREM GRB2 associated, regulator of MAPK1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GIF gastric intrinsic factor (vitamin B synthesis)
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H1E histone cluster 1, H1e
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HOMER2 homer scaffolding protein 2
HOXA6 homeobox A6
HOXC5 homeobox C5
HPN hepsin
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA2 interferon, alpha 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IQCC IQ motif containing C
ISYNA1 inositol-3-phosphate synthase 1
LIME1 Lck interacting transmembrane adaptor 1
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MGC12488
MTERF4 mitochondrial transcription termination factor 4
MUC3A mucin 3A, cell surface associated
NIPAL2 NIPA-like domain containing 2
NPM3 nucleophosmin/nucleoplasmin 3
NTF3 neurotrophin 3
OSMR oncostatin M receptor
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PGPEP1 pyroglutamyl-peptidase I
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRKG2 protein kinase, cGMP-dependent, type II
PRSS22 protease, serine, 22
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RFPL1S RFPL1 antisense RNA 1
RNF146 ring finger protein 146
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
STEAP4 STEAP family member 4
STK16 serine/threonine kinase 16
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLR2 toll-like receptor 2
TMEM242 transmembrane protein 242
TRIM25 tripartite motif containing 25
YPEL1 yippee-like 1 (Drosophila)
ZBTB6 zinc finger and BTB domain containing 6
ZNF225 zinc finger protein 225
ZNF446 zinc finger protein 446
ZNF574 zinc finger protein 574
ZNF84 zinc finger protein 84