metampicillin-5540 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the metampicillin-5540 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAM22 ADAM metallopeptidase domain 22
AKAP7 A kinase (PRKA) anchor protein 7
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APC adenomatous polyposis coli
ARL4C ADP-ribosylation factor-like 4C
ART1 ADP-ribosyltransferase 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
CADM3 cell adhesion molecule 3
CALCR calcitonin receptor
CASP9 caspase 9, apoptosis-related cysteine peptidase
CD300A CD300a molecule
CDK10 cyclin-dependent kinase 10
CDK16 cyclin-dependent kinase 16
CHRDL1 chordin-like 1
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLTA clathrin, light chain A
COPA coatomer protein complex, subunit alpha
CSF1 colony stimulating factor 1 (macrophage)
DCAF8 DDB1 and CUL4 associated factor 8
DEAF1 DEAF1 transcription factor
DHODH dihydroorotate dehydrogenase (quinone)
DLC1 DLC1 Rho GTPase activating protein
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EN2 engrailed homeobox 2
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GAS7 growth arrest-specific 7
GFI1 growth factor independent 1 transcription repressor
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR87 G protein-coupled receptor 87
IFI6 interferon, alpha-inducible protein 6
IFT38 intraflagellar transport 38
IL1B interleukin 1, beta
IL4R interleukin 4 receptor
IRS2 insulin receptor substrate 2
KDM4C lysine (K)-specific demethylase 4C
KLHL20 kelch-like family member 20
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRP12 low density lipoprotein receptor-related protein 12
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAST2 microtubule associated serine/threonine kinase 2
MED25 mediator complex subunit 25
MFGE8 milk fat globule-EGF factor 8 protein
MUC3A mucin 3A, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEK9 NIMA-related kinase 9
NPR3 natriuretic peptide receptor 3
NRG2 neuregulin 2
NSUN6 NOP2/Sun domain family, member 6
OR2W1 olfactory receptor, family 2, subfamily W, member 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB3 protocadherin beta 3
PCNX pecanex homolog (Drosophila)
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF20 PHD finger protein 20
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QPCTL glutaminyl-peptide cyclotransferase-like
RASL11B RAS-like, family 11, member B
RIMS2 regulating synaptic membrane exocytosis 2
RPL10 ribosomal protein L10
RPS9 ribosomal protein S9
SCML2 sex comb on midleg-like 2 (Drosophila)
SFTPC surfactant protein C
SIDT2 SID1 transmembrane family, member 2
SLC12A8 solute carrier family 12, member 8
SLC16A4 solute carrier family 16, member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SLC6A16 solute carrier family 6, member 16
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMG7-AS1 SMG7 antisense RNA 1
SOGA1 suppressor of glucose, autophagy associated 1
SOX15 SRY (sex determining region Y)-box 15
SPATA5L1 spermatogenesis associated 5-like 1
STAC SH3 and cysteine rich domain
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK10 serine/threonine kinase 10
SULT4A1 sulfotransferase family 4A, member 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYBU syntabulin (syntaxin-interacting)
TK2 thymidine kinase 2, mitochondrial
TLDC1 TBC/LysM-associated domain containing 1
TMEM63A transmembrane protein 63A
TTC38 tetratricopeptide repeat domain 38
TTLL3 tubulin tyrosine ligase-like family member 3
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WNT10B wingless-type MMTV integration site family, member 10B
WSCD1 WSC domain containing 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT1 xylosyltransferase I
YTHDC1 YTH domain containing 1
ZFPL1 zinc finger protein-like 1
ZNF747 zinc finger protein 747
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADAM23 ADAM metallopeptidase domain 23
ALG12 ALG12, alpha-1,6-mannosyltransferase
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARC activity-regulated cytoskeleton-associated protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
AUTS2 autism susceptibility candidate 2
BAHCC1 BAH domain and coiled-coil containing 1
BTBD2 BTB (POZ) domain containing 2
C10ORF95 chromosome 10 open reading frame 95
C1ORF105 chromosome 1 open reading frame 105
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMTA1 calmodulin binding transcription activator 1
CASD1 CAS1 domain containing 1
CCNL2 cyclin L2
CCP110 centriolar coiled coil protein 110kDa
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CES3 carboxylesterase 3
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CINP cyclin-dependent kinase 2 interacting protein
CNR2 cannabinoid receptor 2 (macrophage)
CTSF cathepsin F
DHRS3 dehydrogenase/reductase (SDR family) member 3
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
FAM110B family with sequence similarity 110, member B
FAM189A2 family with sequence similarity 189, member A2
FKBP1B FK506 binding protein 1B, 12.6 kDa
GALE UDP-galactose-4-epimerase
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRPR gastrin-releasing peptide receptor
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HCFC2 host cell factor C2
HIRA histone cell cycle regulator
HIST1H2AI histone cluster 1, H2ai
HIST1H2AL histone cluster 1, H2al
HMOX1 heme oxygenase 1
IFT22 intraflagellar transport 22
JMJD4 jumonji domain containing 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD7 potassium channel tetramerization domain containing 7
KDM5C lysine (K)-specific demethylase 5C
KIAA0513 KIAA0513
KIF13B kinesin family member 13B
LAMP3 lysosomal-associated membrane protein 3
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMO2 LIM domain only 2 (rhombotin-like 1)
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAMLD1 mastermind-like domain containing 1
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MSI1 musashi RNA-binding protein 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NABP2 nucleic acid binding protein 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEK2 pleckstrin 2
PODNL1 podocan-like 1
POPDC3 popeye domain containing 3
PPAN peter pan homolog (Drosophila)
RCAN3 RCAN family member 3
RECQL4 RecQ protein-like 4
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF122 ring finger protein 122
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGK1 serum/glucocorticoid regulated kinase 1
SLC22A14 solute carrier family 22, member 14
SLC41A3 solute carrier family 41, member 3
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
TDRD7 tudor domain containing 7
TEX15 testis expressed 15
THOP1 thimet oligopeptidase 1
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSNAXIP1 translin-associated factor X interacting protein 1
TTC30A tetratricopeptide repeat domain 30A
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VN1R1 vomeronasal 1 receptor 1
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZC3H3 zinc finger CCCH-type containing 3
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF350 zinc finger protein 350
ZNF423 zinc finger protein 423