| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the metanephrine-1933 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACLY | ATP citrate lyase |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALMS1 | Alstrom syndrome protein 1 |
| AREG | amphiregulin |
| ARSJ | arylsulfatase family, member J |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BDNF | brain-derived neurotrophic factor |
| CCDC85C | coiled-coil domain containing 85C |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDC5L | cell division cycle 5-like |
| CES3 | carboxylesterase 3 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| COPS7B | COP9 signalosome subunit 7B |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CTH | cystathionine gamma-lyase |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DBR1 | debranching RNA lariats 1 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DUSP4 | dual specificity phosphatase 4 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EPN2 | epsin 2 |
| FBLN1 | fibulin 1 |
| FBXO31 | F-box protein 31 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FCMR | Fc fragment of IgM receptor |
| FGFR1OP | FGFR1 oncogene partner |
| FKSG49 | FKSG49 |
| FNBP1 | formin binding protein 1 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GLRX3 | glutaredoxin 3 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR4 | G protein-coupled receptor 4 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| HAUS2 | HAUS augmin-like complex, subunit 2 |
| HEATR3 | HEAT repeat containing 3 |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL11 | interleukin 11 |
| KIAA1644 | KIAA1644 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MEFV | Mediterranean fever |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MZT2B | mitotic spindle organizing protein 2B |
| NNMT | nicotinamide N-methyltransferase |
| NOTCH1 | notch 1 |
| OPHN1 | oligophrenin 1 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PRDX2 | peroxiredoxin 2 |
| PRKCD | protein kinase C, delta |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPL35A | ribosomal protein L35a |
| SBF1 | SET binding factor 1 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SEC62 | SEC62 homolog (S. cerevisiae) |
| SH2D3A | SH2 domain containing 3A |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SNX15 | sorting nexin 15 |
| SPN | sialophorin |
| SQLE | squalene epoxidase |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TCTN2 | tectonic family member 2 |
| TMEM161A | transmembrane protein 161A |
| TNRC6B | trinucleotide repeat containing 6B |
| TOR4A | torsin family 4, member A |
| TPMT | thiopurine S-methyltransferase |
| TSC22D1 | TSC22 domain family, member 1 |
| UBQLN4 | ubiquilin 4 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WSCD1 | WSC domain containing 1 |
| ZNF160 | zinc finger protein 160 |
| ZNF43 | zinc finger protein 43 |
| ZNF528 | zinc finger protein 528 |
| ZNF552 | zinc finger protein 552 |
| ZNF562 | zinc finger protein 562 |
| ZNF609 | zinc finger protein 609 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |
| Symbol | Name |
|---|---|
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALG5 | ALG5, dolichyl-phosphate beta-glucosyltransferase |
| ANKRD49 | ankyrin repeat domain 49 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 |
| ATG4A | autophagy related 4A, cysteine peptidase |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H |
| ATXN2 | ataxin 2 |
| BMS1 | BMS1 ribosome biogenesis factor |
| C17ORF85 | chromosome 17 open reading frame 85 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLDN14 | claudin 14 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| COL6A3 | collagen, type VI, alpha 3 |
| COQ6 | coenzyme Q6 monooxygenase |
| CROT | carnitine O-octanoyltransferase |
| CTGF | connective tissue growth factor |
| CUEDC2 | CUE domain containing 2 |
| DCAF6 | DDB1 and CUL4 associated factor 6 |
| DNAJC13 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DOCK1 | dedicator of cytokinesis 1 |
| DRD5 | dopamine receptor D5 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EMC2 | ER membrane protein complex subunit 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERCC3 | excision repair cross-complementation group 3 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FAM127B | family with sequence similarity 127, member B |
| FAM188A | family with sequence similarity 188, member A |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| KCTD3 | potassium channel tetramerization domain containing 3 |
| KIAA0556 | KIAA0556 |
| KIF13B | kinesin family member 13B |
| KIF20B | kinesin family member 20B |
| KLHL26 | kelch-like family member 26 |
| KNTC1 | kinetochore associated 1 |
| KPTN | kaptin (actin binding protein) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| METTL21B | methyltransferase like 21B |
| MOXD1 | monooxygenase, DBH-like 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYO9A | myosin IXA |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCTP | phosphatidylcholine transfer protein |
| PGM3 | phosphoglucomutase 3 |
| PHF21A | PHD finger protein 21A |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB36 | RAB36, member RAS oncogene family |
| RAD9A | RAD9 homolog A (S. pombe) |
| RBBP5 | retinoblastoma binding protein 5 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| SEC61B | Sec61 beta subunit |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SNRPC | small nuclear ribonucleoprotein polypeptide C |
| SNX6 | sorting nexin 6 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPA17 | sperm autoantigenic protein 17 |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| TDRD7 | tudor domain containing 7 |
| TEFM | transcription elongation factor, mitochondrial |
| TESK2 | testis-specific kinase 2 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM74B | transmembrane protein 74B |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM45 | tripartite motif containing 45 |
| TTC26 | tetratricopeptide repeat domain 26 |
| VEGFC | vascular endothelial growth factor C |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) |
| WDR37 | WD repeat domain 37 |
| WFS1 | Wolfram syndrome 1 (wolframin) |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF136 | zinc finger protein 136 |
| ZNF175 | zinc finger protein 175 |
| ZNF358 | zinc finger protein 358 |
| ZNF430 | zinc finger protein 430 |
