| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the metanephrine-2015 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABHD3 | abhydrolase domain containing 3 |
| ACVRL1 | activin A receptor type II-like 1 |
| AKTIP | AKT interacting protein |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BCL7A | B-cell CLL/lymphoma 7A |
| BMP1 | bone morphogenetic protein 1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CCDC85C | coiled-coil domain containing 85C |
| CCPG1 | cell cycle progression 1 |
| CD1D | CD1d molecule |
| CD69 | CD69 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| COG5 | component of oligomeric golgi complex 5 |
| COL8A2 | collagen, type VIII, alpha 2 |
| CTSS | cathepsin S |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EIF4E | eukaryotic translation initiation factor 4E |
| ELMO2 | engulfment and cell motility 2 |
| EVI5 | ecotropic viral integration site 5 |
| FCHO1 | FCH domain only 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H4J | histone cluster 1, H4j |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| KIAA1109 | KIAA1109 |
| KIFC1 | kinesin family member C1 |
| KLHL18 | kelch-like family member 18 |
| KLHL20 | kelch-like family member 20 |
| LHB | luteinizing hormone beta polypeptide |
| LIN7C | lin-7 homolog C (C. elegans) |
| LTB4R | leukotriene B4 receptor |
| MAGEB2 | melanoma antigen family B2 |
| MAP7D3 | MAP7 domain containing 3 |
| MICALL1 | MICAL-like 1 |
| MTAP | methylthioadenosine phosphorylase |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PIDD1 | p53-induced death domain protein 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLD2 | phospholipase D2 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PPP1R7 | protein phosphatase 1, regulatory subunit 7 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM25 | RNA binding motif protein 25 |
| RGS1 | regulator of G-protein signaling 1 |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPS2 | ribosomal protein S2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDC2 | syndecan 2 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC35A3 | solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SNX19 | sorting nexin 19 |
| SOCS5 | suppressor of cytokine signaling 5 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| STXBP3 | syntaxin binding protein 3 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYT11 | synaptotagmin XI |
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
| TES | testin LIM domain protein |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TNRC6B | trinucleotide repeat containing 6B |
| TTC37 | tetratricopeptide repeat domain 37 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| WWC2 | WW and C2 domain containing 2 |
| YLPM1 | YLP motif containing 1 |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF224 | zinc finger protein 224 |
| ZNF253 | zinc finger protein 253 |
| ZNF280D | zinc finger protein 280D |
| ZNF500 | zinc finger protein 500 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACACA | acetyl-CoA carboxylase alpha |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ALS2CL | ALS2 C-terminal like |
| ANKRD11 | ankyrin repeat domain 11 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARL2 | ADP-ribosylation factor-like 2 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BCL7B | B-cell CLL/lymphoma 7B |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CGRRF1 | cell growth regulator with ring finger domain 1 |
| CHIC2 | cysteine-rich hydrophobic domain 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| COPS7B | COP9 signalosome subunit 7B |
| COQ6 | coenzyme Q6 monooxygenase |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CSRNP2 | cysteine-serine-rich nuclear protein 2 |
| CTSG | cathepsin G |
| DBF4B | DBF4 zinc finger B |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ECSIT | ECSIT signalling integrator |
| EDC3 | enhancer of mRNA decapping 3 |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| ERCC5 | excision repair cross-complementation group 5 |
| EXOC5 | exocyst complex component 5 |
| FMO4 | flavin containing monooxygenase 4 |
| GAB2 | GRB2-associated binding protein 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GPR27 | G protein-coupled receptor 27 |
| GSR | glutathione reductase |
| GSTM5 | glutathione S-transferase mu 5 |
| HK1 | hexokinase 1 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| INO80D | INO80 complex subunit D |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KRT38 | keratin 38, type I |
| LAS1L | LAS1-like (S. cerevisiae) |
| MKKS | McKusick-Kaufman syndrome |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTRF1 | mitochondrial translational release factor 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MYLIP | myosin regulatory light chain interacting protein |
| MYO19 | myosin XIX |
| NADSYN1 | NAD synthetase 1 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NCKAP1L | NCK-associated protein 1-like |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NEK11 | NIMA-related kinase 11 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OR7E37P | olfactory receptor, family 7, subfamily E, member 37 pseudogene |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PGPEP1 | pyroglutamyl-peptidase I |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PKN1 | protein kinase N1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RAB8B | RAB8B, member RAS oncogene family |
| RABGGTA | Rab geranylgeranyltransferase, alpha subunit |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SIRT6 | sirtuin 6 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNX6 | sorting nexin 6 |
| SRRD | SRR1 domain containing |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| STRA13 | stimulated by retinoic acid 13 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCTN2 | tectonic family member 2 |
| TMEM50A | transmembrane protein 50A |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TYW1 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USB1 | U6 snRNA biogenesis 1 |
| WDR77 | WD repeat domain 77 |
| XDH | xanthine dehydrogenase |
| YIPF1 | Yip1 domain family, member 1 |
| YY2 | YY2 transcription factor |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF606 | zinc finger protein 606 |