metanephrine-5334 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the metanephrine-5334 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APC adenomatous polyposis coli
ATP9A ATPase, class II, type 9A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BTBD7 BTB (POZ) domain containing 7
CACTIN cactin, spliceosome C complex subunit
CD58 CD58 molecule
CDC25C cell division cycle 25C
CEP162 centrosomal protein 162kDa
CEP164 centrosomal protein 164kDa
CEP63 centrosomal protein 63kDa
COBLL1 cordon-bleu WH2 repeat protein-like 1
CREBZF CREB/ATF bZIP transcription factor
CTH cystathionine gamma-lyase
DACH1 dachshund family transcription factor 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIEXF digestive organ expansion factor homolog (zebrafish)
DIO2 deiodinase, iodothyronine, type II
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DSC2 desmocollin 2
DST dystonin
EPN2 epsin 2
FAM184A family with sequence similarity 184, member A
FBLN1 fibulin 1
FBXO9 F-box protein 9
FKBP5 FK506 binding protein 5
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR35 G protein-coupled receptor 35
HDAC11 histone deacetylase 11
HDAC4 histone deacetylase 4
HDLBP high density lipoprotein binding protein
HIST1H2AJ histone cluster 1, H2aj
HMOX1 heme oxygenase 1
HOMER3 homer scaffolding protein 3
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
KIF3C kinesin family member 3C
LIME1 Lck interacting transmembrane adaptor 1
LPCAT3 lysophosphatidylcholine acyltransferase 3
LRRC20 leucine rich repeat containing 20
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC49 leucine rich repeat containing 49
LYST lysosomal trafficking regulator
MARK4 MAP/microtubule affinity-regulating kinase 4
METTL7A methyltransferase like 7A
MLF1 myeloid leukemia factor 1
N4BP1 NEDD4 binding protein 1
NEK1 NIMA-related kinase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOP16 NOP16 nucleolar protein
NOTCH2 notch 2
NPR2 natriuretic peptide receptor 2
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PARP12 poly (ADP-ribose) polymerase family, member 12
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PER1 period circadian clock 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
RAB11B RAB11B, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RECQL5 RecQ protein-like 5
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RSL1D1 ribosomal L1 domain containing 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3BP2 SH3-domain binding protein 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SIK2 salt-inducible kinase 2
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SOCS2 suppressor of cytokine signaling 2
ST7 suppression of tumorigenicity 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK4 serine/threonine kinase 4
STMN1 stathmin 1
SYBU syntabulin (syntaxin-interacting)
SZRD1 SUZ RNA binding domain containing 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAZ tafazzin
TM2D1 TM2 domain containing 1
TMCC2 transmembrane and coiled-coil domain family 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM242 transmembrane protein 242
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRIP11 thyroid hormone receptor interactor 11
TTC38 tetratricopeptide repeat domain 38
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
VASH1 vasohibin 1
ZBED4 zinc finger, BED-type containing 4
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF609 zinc finger protein 609
ZNF862 zinc finger protein 862
ZYX zyxin

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACYP1 acylphosphatase 1, erythrocyte (common) type
ANXA2P3 annexin A2 pseudogene 3
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
AUH AU RNA binding protein/enoyl-CoA hydratase
BAHD1 bromo adjacent homology domain containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTF3P11 basic transcription factor 3 pseudogene 11
C1ORF216 chromosome 1 open reading frame 216
C9ORF40 chromosome 9 open reading frame 40
CDK20 cyclin-dependent kinase 20
CENPJ centromere protein J
CFAP44 cilia and flagella associated protein 44
CLCN5 chloride channel, voltage-sensitive 5
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CUL9 cullin 9
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENR density-regulated protein
DUSP8 dual specificity phosphatase 8
EDC3 enhancer of mRNA decapping 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EVPL envoplakin
FAM222B family with sequence similarity 222, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCHO1 FCH domain only 1
FHOD1 formin homology 2 domain containing 1
FOXJ2 forkhead box J2
FURIN furin (paired basic amino acid cleaving enzyme)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GBP2 guanylate binding protein 2, interferon-inducible
GLI3 GLI family zinc finger 3
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HOXC10 homeobox C10
IDI2-AS1 IDI2 antisense RNA 1
IMPACT impact RWD domain protein
INF2 inverted formin, FH2 and WH2 domain containing
JADE1 jade family PHD finger 1
KAT2A K(lysine) acetyltransferase 2A
KLF11 Kruppel-like factor 11
KRCC1 lysine-rich coiled-coil 1
LMNB1 lamin B1
LOC100272216 uncharacterized LOC100272216
LOC390998 ribosomal protein L10 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
LY6D lymphocyte antigen 6 complex, locus D
LYPLA2P1 lysophospholipase II pseudogene 1
MANBA mannosidase, beta A, lysosomal
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MITF microphthalmia-associated transcription factor
MUM1 melanoma associated antigen (mutated) 1
MXD3 MAX dimerization protein 3
NAA38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit
PER3 period circadian clock 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PNKP polynucleotide kinase 3'-phosphatase
PPOX protoporphyrinogen oxidase
PRICKLE3 prickle homolog 3 (Drosophila)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRU protein tyrosine phosphatase, receptor type, U
PUS1 pseudouridylate synthase 1
RECQL4 RecQ protein-like 4
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFTN1 raftlin, lipid raft linker 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SETD8 SET domain containing (lysine methyltransferase) 8
SGK1 serum/glucocorticoid regulated kinase 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC46A3 solute carrier family 46, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA20 spermatogenesis associated 20
TEX30 testis expressed 30
THAP1 THAP domain containing, apoptosis associated protein 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLN1 talin 1
TMEM57 transmembrane protein 57
TMPRSS3 transmembrane protease, serine 3
TNK1 tyrosine kinase, non-receptor, 1
TNRC6B trinucleotide repeat containing 6B
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
WDR19 WD repeat domain 19
WDR60 WD repeat domain 60
ZFP69B ZFP69 zinc finger protein B
ZMAT5 zinc finger, matrin-type 5
ZNF227 zinc finger protein 227
ZNF324 zinc finger protein 324
ZNF639 zinc finger protein 639
ZNF668 zinc finger protein 668
ZNF767P zinc finger family member 767, pseudogene
ZNF778 zinc finger protein 778
ZSCAN9 zinc finger and SCAN domain containing 9