metaplasia Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division. (Gene Ontology, GO_0036074)
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Genes

113 genes co-occuring with the biological term metaplasia in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ALOX5 arachidonate 5-lipoxygenase
ANO1 anoctamin 1, calcium activated chloride channel
BCL2 B-cell CLL/lymphoma 2
BCL6 B-cell CLL/lymphoma 6
BHLHA15 basic helix-loop-helix family, member a15
BMP4 bone morphogenetic protein 4
C1QA complement component 1, q subcomponent, A chain
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL5 chemokine (C-C motif) ligand 5
CD1A CD1a molecule
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CLCA1 chloride channel accessory 1
CLDN2 claudin 2
CLDN3 claudin 3
CLDN4 claudin 4
CLDN5 claudin 5
CLDN7 claudin 7
COMT catechol-O-methyltransferase
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYBA cytochrome b-245, alpha polypeptide
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEFA5 defensin, alpha 5, Paneth cell-specific
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
EMP1 epithelial membrane protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF9 fibroblast growth factor 9
FOXA3 forkhead box A3
GAST gastrin
GDF15 growth differentiation factor 15
GLI1 GLI family zinc finger 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GUCY2C guanylate cyclase 2C
HMGA2 high mobility group AT-hook 2
HSPB1 heat shock 27kDa protein 1
IFIH1 interferon induced with helicase C domain 1
IL10 interleukin 10
IL13 interleukin 13
IL1B interleukin 1, beta
JAK2 Janus kinase 2
KLF5 Kruppel-like factor 5 (intestinal)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT20 keratin 20, type I
KRT7 keratin 7, type II
MAML2 mastermind-like 2 (Drosophila)
MET MET proto-oncogene, receptor tyrosine kinase
MIR1290 microRNA 1290
MIR584 microRNA 584
MKI67 marker of proliferation Ki-67
MMP9 matrix metallopeptidase 9
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MUC1 mucin 1, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NKX6-1 NK6 homeobox 1
NOD1 nucleotide-binding oligomerization domain containing 1
NQO1 NAD(P)H dehydrogenase, quinone 1
OCLN occludin
ONECUT1 one cut homeobox 1
PAX6 paired box 6
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PGA3 pepsinogen 3, group I (pepsinogen A)
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RARB retinoic acid receptor, beta
REG4 regenerating islet-derived family, member 4
RUNX1 runt-related transcription factor 1
RUNX3 runt-related transcription factor 3
SALL4 spalt-like transcription factor 4
SHH sonic hedgehog
SIRT1 sirtuin 1
SLPI secretory leukocyte peptidase inhibitor
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPRR1B small proline-rich protein 1B
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TERT telomerase reverse transcriptase
TIMP1 TIMP metallopeptidase inhibitor 1
TJP1 tight junction protein 1
TP53 tumor protein p53
TYMS thymidylate synthetase
VEGFA vascular endothelial growth factor A
VILL villin-like
WNT7B wingless-type MMTV integration site family, member 7B