metaraminol-2298 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the metaraminol-2298 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGRN agrin
AHNAK2 AHNAK nucleoprotein 2
ASB1 ankyrin repeat and SOCS box containing 1
ASMT acetylserotonin O-methyltransferase
ATHL1 ATH1, acid trehalase-like 1 (yeast)
BGN biglycan
C17ORF59 chromosome 17 open reading frame 59
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALB2 calbindin 2
CD1B CD1b molecule
CD200 CD200 molecule
CD300C CD300c molecule
CD80 CD80 molecule
CD8A CD8a molecule
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CELP carboxyl ester lipase pseudogene
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLCN4 chloride channel, voltage-sensitive 4
CLUL1 clusterin-like 1 (retinal)
COL1A2 collagen, type I, alpha 2
CRHR2 corticotropin releasing hormone receptor 2
CRYAB crystallin, alpha B
CSF1 colony stimulating factor 1 (macrophage)
CXCR6 chemokine (C-X-C motif) receptor 6
DGAT1 diacylglycerol O-acyltransferase 1
DLK2 delta-like 2 homolog (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EPN1 epsin 1
ERCC2 excision repair cross-complementation group 2
FABP3 fatty acid binding protein 3, muscle and heart
FAM155A family with sequence similarity 155, member A
FANCA Fanconi anemia, complementation group A
FBXL7 F-box and leucine-rich repeat protein 7
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF18 fibroblast growth factor 18
FLJ21369 uncharacterized protein FLJ21369
GJB4 gap junction protein, beta 4, 30.3kDa
GLS glutaminase
GREB1 growth regulation by estrogen in breast cancer 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GUK1 guanylate kinase 1
HHAT hedgehog acyltransferase
HRH2 histamine receptor H2
IDS iduronate 2-sulfatase
IGLJ3 immunoglobulin lambda joining 3
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
INPP5J inositol polyphosphate-5-phosphatase J
IRF4 interferon regulatory factor 4
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
JPH3 junctophilin 3
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCTD13 potassium channel tetramerization domain containing 13
KHK ketohexokinase (fructokinase)
LAMC3 laminin, gamma 3
LAMP1 lysosomal-associated membrane protein 1
MAGEA1 melanoma antigen family A1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MUC13 mucin 13, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEUROD4 neuronal differentiation 4
NRTN neurturin
NTF3 neurotrophin 3
PAGE1 P antigen family, member 1 (prostate associated)
PAX8 paired box 8
PCDHGA8 protocadherin gamma subfamily A, 8
PCNX pecanex homolog (Drosophila)
PDZRN4 PDZ domain containing ring finger 4
PKNOX2 PBX/knotted 1 homeobox 2
PLCD1 phospholipase C, delta 1
PYHIN1 pyrin and HIN domain family, member 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SFTPB surfactant protein B
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SNRPN small nuclear ribonucleoprotein polypeptide N
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SQSTM1 sequestosome 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYP synaptophysin
TAS2R9 taste receptor, type 2, member 9
TCHH trichohyalin
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPC4 transient receptor potential cation channel, subfamily C, member 4
TYMP thymidine phosphorylase
ZCCHC4 zinc finger, CCHC domain containing 4

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM15 ADAM metallopeptidase domain 15
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
APOC1 apolipoprotein C-I
ARL15 ADP-ribosylation factor-like 15
ARRB1 arrestin, beta 1
ASAP1-IT1 ASAP1 intronic transcript 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C19ORF73 chromosome 19 open reading frame 73
C1ORF56 chromosome 1 open reading frame 56
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CA5BP1 carbonic anhydrase VB pseudogene 1
CD302 CD302 molecule
CD83 CD83 molecule
CLCN6 chloride channel, voltage-sensitive 6
CLDND1 claudin domain containing 1
CPPED1 calcineurin-like phosphoesterase domain containing 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELP3 elongator acetyltransferase complex subunit 3
EML4 echinoderm microtubule associated protein like 4
EPHX2 epoxide hydrolase 2, cytoplasmic
F2R coagulation factor II (thrombin) receptor
FOXI1 forkhead box I1
FSD1 fibronectin type III and SPRY domain containing 1
GAMT guanidinoacetate N-methyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPR21 G protein-coupled receptor 21
HIST1H1D histone cluster 1, H1d
HIST1H2BC histone cluster 1, H2bc
HIST1H3B histone cluster 1, H3b
HIST1H4D histone cluster 1, H4d
HS1BP3 HCLS1 binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDI2-AS1 IDI2 antisense RNA 1
JMJD4 jumonji domain containing 4
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KEL Kell blood group, metallo-endopeptidase
KIAA0125 KIAA0125
KIAA0895 KIAA0895
KLF2 Kruppel-like factor 2
KLHL21 kelch-like family member 21
LOXL1 lysyl oxidase-like 1
LRRC49 leucine rich repeat containing 49
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP9 microtubule-associated protein 9
METTL16 methyltransferase like 16
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NPIPB3 nuclear pore complex interacting protein family, member B3
NPM3 nucleophosmin/nucleoplasmin 3
PARPBP PARP1 binding protein
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PITX2 paired-like homeodomain 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PRPH peripherin
PRR7 proline rich 7 (synaptic)
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3D RAB3D, member RAS oncogene family
RAB5C RAB5C, member RAS oncogene family
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCOR3 REST corepressor 3
RGS17 regulator of G-protein signaling 17
RGS19 regulator of G-protein signaling 19
RIN2 Ras and Rab interactor 2
RNF121 ring finger protein 121
SCN1B sodium channel, voltage gated, type I beta subunit
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SETD8 SET domain containing (lysine methyltransferase) 8
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLIT2 slit homolog 2 (Drosophila)
SMIM14 small integral membrane protein 14
SND1-IT1 SND1 intronic transcript 1
SP1 Sp1 transcription factor
SPON2 spondin 2, extracellular matrix protein
SRD5A3 steroid 5 alpha-reductase 3
SSFA2 sperm specific antigen 2
STAB2 stabilin 2
TCP10 t-complex 10
TCTA T-cell leukemia translocation altered
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM25 tripartite motif containing 25
TTC33 tetratricopeptide repeat domain 33
UBQLN4 ubiquilin 4
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USP27X ubiquitin specific peptidase 27, X-linked
USP6NL USP6 N-terminal like
ZBED8 zinc finger, BED-type containing 8
ZNF10 zinc finger protein 10
ZNF350 zinc finger protein 350
ZNF365 zinc finger protein 365
ZNF432 zinc finger protein 432
ZNF586 zinc finger protein 586
ZNF862 zinc finger protein 862