metaraminol-3669 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the metaraminol-3669 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM23 ADAM metallopeptidase domain 23
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADCK2 aarF domain containing kinase 2
AHSG alpha-2-HS-glycoprotein
ANXA10 annexin A10
AQP3 aquaporin 3 (Gill blood group)
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATP10B ATPase, class V, type 10B
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCL2A1 BCL2-related protein A1
BMP2 bone morphogenetic protein 2
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CCR10 chemokine (C-C motif) receptor 10
CD4 CD4 molecule
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEMIP cell migration inducing protein, hyaluronan binding
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CLEC4M C-type lectin domain family 4, member M
CNTNAP2 contactin associated protein-like 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXCL2 chemokine (C-X-C motif) ligand 2
DIO2 deiodinase, iodothyronine, type II
DMBT1 deleted in malignant brain tumors 1
DUSP1 dual specificity phosphatase 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ENG endoglin
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FLJ11710 uncharacterized protein FLJ11710
FOLR1 folate receptor 1 (adult)
GK glycerol kinase
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GRIP2 glutamate receptor interacting protein 2
GRTP1 growth hormone regulated TBC protein 1
HAL histidine ammonia-lyase
HFE hemochromatosis
HIST1H2AL histone cluster 1, H2al
HIST1H2BM histone cluster 1, H2bm
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
IFI44L interferon-induced protein 44-like
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL11 interleukin 11
IL2RG interleukin 2 receptor, gamma
ING4 inhibitor of growth family, member 4
INSL4 insulin-like 4 (placenta)
ISG20 interferon stimulated exonuclease gene 20kDa
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
LOC100287590 uncharacterized LOC100287590
LYRM9 LYR motif containing 9
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MEF2D myocyte enhancer factor 2D
MEGF6 multiple EGF-like-domains 6
MEOX2 mesenchyme homeobox 2
N4BP1 NEDD4 binding protein 1
NELL2 NEL-like 2 (chicken)
NLRP3 NLR family, pyrin domain containing 3
NME5 NME/NM23 family member 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOX1 NADPH oxidase 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OXCT2 3-oxoacid CoA transferase 2
PCDHA5 protocadherin alpha 5
PDE4B phosphodiesterase 4B, cAMP-specific
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGLYRP4 peptidoglycan recognition protein 4
PID1 phosphotyrosine interaction domain containing 1
PLXND1 plexin D1
PRKCE protein kinase C, epsilon
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
RGS17 regulator of G-protein signaling 17
RIMS3 regulating synaptic membrane exocytosis 3
RNF43 ring finger protein 43
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFTPB surfactant protein B
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SOX21 SRY (sex determining region Y)-box 21
SPANXC SPANX family, member C
SRSF7 serine/arginine-rich splicing factor 7
STARD8 StAR-related lipid transfer (START) domain containing 8
STAT4 signal transducer and activator of transcription 4
STC1 stanniocalcin 1
SYN2 synapsin II
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D30 TBC1 domain family, member 30
TFR2 transferrin receptor 2
TRIM3 tripartite motif containing 3
TSKS testis-specific serine kinase substrate
USP46 ubiquitin specific peptidase 46
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADRB2 adrenoceptor beta 2, surface
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
BDKRB1 bradykinin receptor B1
BIRC3 baculoviral IAP repeat containing 3
C14ORF79 chromosome 14 open reading frame 79
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMKMT calmodulin-lysine N-methyltransferase
CD101 CD101 molecule
CDH7 cadherin 7, type 2
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CDON cell adhesion associated, oncogene regulated
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTGF connective tissue growth factor
DBR1 debranching RNA lariats 1
DDB2 damage-specific DNA binding protein 2, 48kDa
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSCAM Down syndrome cell adhesion molecule
EPN1 epsin 1
FSD1 fibronectin type III and SPRY domain containing 1
GAL3ST4 galactose-3-O-sulfotransferase 4
GALK1 galactokinase 1
GAS8 growth arrest-specific 8
GBX2 gastrulation brain homeobox 2
GJA8 gap junction protein, alpha 8, 50kDa
GLS2 glutaminase 2 (liver, mitochondrial)
HDAC11 histone deacetylase 11
HDAC9 histone deacetylase 9
HIST1H1T histone cluster 1, H1t
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL22 interleukin 22
INHBB inhibin, beta B
IRAK4 interleukin-1 receptor-associated kinase 4
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KIAA1549L KIAA1549-like
KRT15 keratin 15, type I
LAMC3 laminin, gamma 3
LAX1 lymphocyte transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
LOC257152 uncharacterized LOC257152
LRRK1 leucine-rich repeat kinase 1
MAK male germ cell-associated kinase
MAL mal, T-cell differentiation protein
MBNL3 muscleblind-like splicing regulator 3
MLYCD malonyl-CoA decarboxylase
MNT MAX network transcriptional repressor
MXRA8 matrix-remodelling associated 8
MYO1D myosin ID
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NR3C2 nuclear receptor subfamily 3, group C, member 2
PARPBP PARP1 binding protein
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRR15L proline rich 15-like
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RABL6 RAB, member RAS oncogene family-like 6
RNF126P1 ring finger protein 126 pseudogene 1
RNF146 ring finger protein 146
ROM1 retinal outer segment membrane protein 1
RPA4 replication protein A4, 30kDa
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGK2 serum/glucocorticoid regulated kinase 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC46A3 solute carrier family 46, member 3
STAB2 stabilin 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TUBA3C tubulin, alpha 3c
UNC93B1 unc-93 homolog B1 (C. elegans)
USP20 ubiquitin specific peptidase 20
WNT7A wingless-type MMTV integration site family, member 7A
WT1-AS WT1 antisense RNA
ZBTB22 zinc finger and BTB domain containing 22
ZNF415 zinc finger protein 415
ZNF749 zinc finger protein 749
ZNF93 zinc finger protein 93