meteneprost-7504 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the meteneprost-7504 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADARB1 adenosine deaminase, RNA-specific, B1
ADCY1 adenylate cyclase 1 (brain)
ADGRB2 adhesion G protein-coupled receptor B2
ADRBK1 adrenergic, beta, receptor kinase 1
AGGF1 angiogenic factor with G patch and FHA domains 1
ANGPTL4 angiopoietin-like 4
APP amyloid beta (A4) precursor protein
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARL14 ADP-ribosylation factor-like 14
ARL4D ADP-ribosylation factor-like 4D
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BLZF1 basic leucine zipper nuclear factor 1
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
BRWD1 bromodomain and WD repeat domain containing 1
C1ORF56 chromosome 1 open reading frame 56
CA12 carbonic anhydrase XII
CASP8AP2 caspase 8 associated protein 2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CLCN6 chloride channel, voltage-sensitive 6
CLDN1 claudin 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CPA4 carboxypeptidase A4
CPT1A carnitine palmitoyltransferase 1A (liver)
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND2A DENN/MADD domain containing 2A
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DMBT1 deleted in malignant brain tumors 1
DNAH3 dynein, axonemal, heavy chain 3
DUSP1 dual specificity phosphatase 1
ELOVL4 ELOVL fatty acid elongase 4
ESRP2 epithelial splicing regulatory protein 2
ESRRA estrogen-related receptor alpha
FABP4 fatty acid binding protein 4, adipocyte
FAM53B family with sequence similarity 53, member B
FBN2 fibrillin 2
FBXO41 F-box protein 41
FGFR1 fibroblast growth factor receptor 1
FPGS folylpolyglutamate synthase
GCFC2 GC-rich sequence DNA-binding factor 2
GLDC glycine dehydrogenase (decarboxylating)
HAUS6 HAUS augmin-like complex, subunit 6
HHEX hematopoietically expressed homeobox
HOXB6 homeobox B6
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM4B lysine (K)-specific demethylase 4B
LAMC2 laminin, gamma 2
LIG3 ligase III, DNA, ATP-dependent
LMF1 lipase maturation factor 1
LYPD3 LY6/PLAUR domain containing 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP7 microtubule-associated protein 7
MKL1 megakaryoblastic leukemia (translocation) 1
MOB3B MOB kinase activator 3B
MRPS12 mitochondrial ribosomal protein S12
MXRA8 matrix-remodelling associated 8
NAT6 N-acetyltransferase 6 (GCN5-related)
NCOA1 nuclear receptor coactivator 1
NLE1 notchless homolog 1 (Drosophila)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PHC1 polyhomeotic homolog 1 (Drosophila)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCE1 phospholipase C, epsilon 1
PPP5C protein phosphatase 5, catalytic subunit
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTHLH parathyroid hormone-like hormone
PTPRR protein tyrosine phosphatase, receptor type, R
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RAB31 RAB31, member RAS oncogene family
RARG retinoic acid receptor, gamma
RNF216 ring finger protein 216
S100A3 S100 calcium binding protein A3
SARM1 sterile alpha and TIR motif containing 1
SCARB2 scavenger receptor class B, member 2
SH2D4A SH2 domain containing 4A
SIX2 SIX homeobox 2
SLC43A3 solute carrier family 43, member 3
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
STAT1 signal transducer and activator of transcription 1, 91kDa
SYT17 synaptotagmin XVII
TFF2 trefoil factor 2
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM80 transmembrane protein 80
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TPI1 triosephosphate isomerase 1
TTLL5 tubulin tyrosine ligase-like family member 5
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
UNC119 unc-119 homolog (C. elegans)
URGCP upregulator of cell proliferation
VWA9 von Willebrand factor A domain containing 9
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF574 zinc finger protein 574
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTG2 actin, gamma 2, smooth muscle, enteric
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC4 armadillo repeat containing 4
ATXN8OS ATXN8 opposite strand (non-protein coding)
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
C1RL complement component 1, r subcomponent-like
C5ORF45 chromosome 5 open reading frame 45
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLTCL1 clathrin, heavy chain-like 1
CORT cortistatin
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DIO3 deiodinase, iodothyronine, type III
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETV7 ets variant 7
EXD3 exonuclease 3'-5' domain containing 3
EXO5 exonuclease 5
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM186A family with sequence similarity 186, member A
FZD10 frizzled class receptor 10
GEMIN8 gem (nuclear organelle) associated protein 8
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRTP1 growth hormone regulated TBC protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
IL33 interleukin 33
INSIG2 insulin induced gene 2
IPO8 importin 8
KCNK13 potassium channel, two pore domain subfamily K, member 13
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KLHL28 kelch-like family member 28
LIME1 Lck interacting transmembrane adaptor 1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LY6H lymphocyte antigen 6 complex, locus H
MAGEF1 melanoma antigen family F1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MPP1 membrane protein, palmitoylated 1, 55kDa
MRAS muscle RAS oncogene homolog
MUC3B mucin 3B, cell surface associated
MX2 MX dynamin-like GTPase 2
MYBPC3 myosin binding protein C, cardiac
MYOZ3 myozenin 3
MYRIP myosin VIIA and Rab interacting protein
NME5 NME/NM23 family member 5
NR3C2 nuclear receptor subfamily 3, group C, member 2
OSGIN1 oxidative stress induced growth inhibitor 1
PADI1 peptidyl arginine deiminase, type I
POM121 POM121 transmembrane nucleoporin
PRPH peripherin
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAI2 retinoic acid induced 2
RND1 Rho family GTPase 1
SCNN1B sodium channel, non voltage gated 1 beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMA4 glucuronidase, beta pseudogene
SPIDR scaffolding protein involved in DNA repair
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNC syncoilin, intermediate filament protein
TAOK1 TAO kinase 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN2 tectonic family member 2
TENM1 teneurin transmembrane protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TIMP4 TIMP metallopeptidase inhibitor 4
TM4SF5 transmembrane 4 L six family member 5
TMEM159 transmembrane protein 159
TMEM57 transmembrane protein 57
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM45 tripartite motif containing 45
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA4B tubulin, alpha 4b
TULP1 tubby like protein 1
UTF1 undifferentiated embryonic cell transcription factor 1
VGF VGF nerve growth factor inducible
WDR76 WD repeat domain 76
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZNF219 zinc finger protein 219
ZNF280D zinc finger protein 280D
ZNF286A zinc finger protein 286A
ZNF668 zinc finger protein 668
ZNF74 zinc finger protein 74