metergoline-1606 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

198 genes differentially expressed following the metergoline-1606 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ACP6 acid phosphatase 6, lysophosphatidic
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
AMBRA1 autophagy/beclin-1 regulator 1
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ASB8 ankyrin repeat and SOCS box containing 8
ATXN2 ataxin 2
AVEN apoptosis, caspase activation inhibitor
C11ORF21 chromosome 11 open reading frame 21
C2ORF44 chromosome 2 open reading frame 44
C7ORF43 chromosome 7 open reading frame 43
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CXCL8 chemokine (C-X-C motif) ligand 8
CYLD cylindromatosis (turban tumor syndrome)
DHCR7 7-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSCR3 Down syndrome critical region 3
E2F1 E2F transcription factor 1
EGR3 early growth response 3
EMC1 ER membrane protein complex subunit 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FASTK Fas-activated serine/threonine kinase
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
G6PD glucose-6-phosphate dehydrogenase
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GFER growth factor, augmenter of liver regeneration
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GOLM1 golgi membrane protein 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GSE1 Gse1 coiled-coil protein
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AC histone cluster 1, H2ac
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
KDM6B lysine (K)-specific demethylase 6B
KIZ kizuna centrosomal protein
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LY96 lymphocyte antigen 96
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MAPKBP1 mitogen-activated protein kinase binding protein 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MXD4 MAX dimerization protein 4
NAT6 N-acetyltransferase 6 (GCN5-related)
NDE1 nudE neurodevelopment protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPEPPS aminopeptidase puromycin sensitive
NR2F6 nuclear receptor subfamily 2, group F, member 6
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OSGIN2 oxidative stress induced growth inhibitor family member 2
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PHF3 PHD finger protein 3
PLCB2 phospholipase C, beta 2
PLCD1 phospholipase C, delta 1
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PPARG peroxisome proliferator-activated receptor gamma
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PTX3 pentraxin 3, long
RABL3 RAB, member of RAS oncogene family-like 3
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
REEP1 receptor accessory protein 1
RGS2 regulator of G-protein signaling 2
RNF144A ring finger protein 144A
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SC5D sterol-C5-desaturase
SCCPDH saccharopine dehydrogenase (putative)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SETD4 SET domain containing 4
SF3A2 splicing factor 3a, subunit 2, 66kDa
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SMAD7 SMAD family member 7
SNX11 sorting nexin 11
SQLE squalene epoxidase
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STXBP1 syntaxin binding protein 1
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TMEM161A transmembrane protein 161A
TMEM97 transmembrane protein 97
TRIM26 tripartite motif containing 26
TSC22D3 TSC22 domain family, member 3
TULP3 tubby like protein 3
UBQLN4 ubiquilin 4
UNC119B unc-119 homolog B (C. elegans)
UNC45A unc-45 homolog A (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
VILL villin-like
VPS33B vacuolar protein sorting 33 homolog B (yeast)
YIPF4 Yip1 domain family, member 4

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ABT1 activator of basal transcription 1
ACVR2B activin A receptor, type IIB
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATG14 autophagy related 14
AUH AU RNA binding protein/enoyl-CoA hydratase
C6ORF47 chromosome 6 open reading frame 47
CAPN7 calpain 7
CCDC47 coiled-coil domain containing 47
CCL2 chemokine (C-C motif) ligand 2
CD248 CD248 molecule, endosialin
CD82 CD82 molecule
CDK5 cyclin-dependent kinase 5
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CISH cytokine inducible SH2-containing protein
CNTD2 cyclin N-terminal domain containing 2
CRTAP cartilage associated protein
CST3 cystatin C
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DBF4 DBF4 zinc finger
DCTPP1 dCTP pyrophosphatase 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EBNA1BP2 EBNA1 binding protein 2
EDAR ectodysplasin A receptor
FADD Fas (TNFRSF6)-associated via death domain
FMO4 flavin containing monooxygenase 4
FRG1 FSHD region gene 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCLM glutamate-cysteine ligase, modifier subunit
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR27 G protein-coupled receptor 27
GTF2IRD1 GTF2I repeat domain containing 1
HMGB3P1 high mobility group box 3 pseudogene 1
HOOK2 hook microtubule-tethering protein 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM3 interferon induced transmembrane protein 3
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
JMJD1C jumonji domain containing 1C
KIAA0922 KIAA0922
LACTB2 lactamase, beta 2
LASP1 LIM and SH3 protein 1
LOC729164 hCG1732469
LRP3 low density lipoprotein receptor-related protein 3
MAN1C1 mannosidase, alpha, class 1C, member 1
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MED15 mediator complex subunit 15
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MORC3 MORC family CW-type zinc finger 3
MPP1 membrane protein, palmitoylated 1, 55kDa
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPS15 mitochondrial ribosomal protein S15
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUTYH mutY homolog
MYO19 myosin XIX
MYO1F myosin IF
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing
NAP1L4 nucleosome assembly protein 1-like 4
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
PAK1IP1 PAK1 interacting protein 1
PARG poly (ADP-ribose) glycohydrolase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRR3 proline rich 3
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAB1B RAB1B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RFPL3 ret finger protein-like 3
RNF123 ring finger protein 123
RNMTL1 RNA methyltransferase like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL34 ribosomal protein L34
RRP1 ribosomal RNA processing 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SATB1 SATB homeobox 1
SDCCAG3 serologically defined colon cancer antigen 3
SECISBP2 SECIS binding protein 2
SIRT6 sirtuin 6
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
SLMO2 slowmo homolog 2 (Drosophila)
STAC SH3 and cysteine rich domain
THBS4 thrombospondin 4
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TPX2 TPX2, microtubule-associated
TRIP10 thyroid hormone receptor interactor 10
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TXLNA taxilin alpha
WFDC2 WAP four-disulfide core domain 2
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF140 zinc finger protein 140
ZNF189 zinc finger protein 189
ZNF197 zinc finger protein 197
ZNF211 zinc finger protein 211