| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the metergoline-3221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 |
| AFAP1 | actin filament associated protein 1 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| APOE | apolipoprotein E |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA4 | carbonic anhydrase IV |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD101 | CD101 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CIC | capicua transcriptional repressor |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| CTRL | chymotrypsin-like |
| DCN | decorin |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGR1 | early growth response 1 |
| FAM182B | family with sequence similarity 182, member B |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FH | fumarate hydratase |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLB1L | galactosidase, beta 1-like |
| HBS1L | HBS1-like translational GTPase |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IFT27 | intraflagellar transport 27 |
| IGL | immunoglobulin lambda locus |
| INHBE | inhibin, beta E |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LPIN1 | lipin 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MARS | methionyl-tRNA synthetase |
| MSMO1 | methylsterol monooxygenase 1 |
| MST1 | macrophage stimulating 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MVK | mevalonate kinase |
| NFIB | nuclear factor I/B |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OBSL1 | obscurin-like 1 |
| OMD | osteomodulin |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PLA2G3 | phospholipase A2, group III |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PVRL3 | poliovirus receptor-related 3 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RAI2 | retinoic acid induced 2 |
| RND1 | Rho family GTPase 1 |
| SETD1B | SET domain containing 1B |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SLN | sarcolipin |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SP100 | SP100 nuclear antigen |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SQLE | squalene epoxidase |
| SSPN | sarcospan |
| STEAP4 | STEAP family member 4 |
| TBX6 | T-box 6 |
| TEX14 | testis expressed 14 |
| TEX40 | testis expressed 40 |
| TMEM53 | transmembrane protein 53 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase |
| TPMT | thiopurine S-methyltransferase |
| TRIM2 | tripartite motif containing 2 |
| TSC2 | tuberous sclerosis 2 |
| UCN | urocortin |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ART1 | ADP-ribosyltransferase 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC9 | coiled-coil domain containing 9 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD83 | CD83 molecule |
| CES1 | carboxylesterase 1 |
| CFAP45 | cilia and flagella associated protein 45 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CORO7 | coronin 7 |
| CRYGC | crystallin, gamma C |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| DAGLA | diacylglycerol lipase, alpha |
| DEAF1 | DEAF1 transcription factor |
| DPYS | dihydropyrimidinase |
| DUSP13 | dual specificity phosphatase 13 |
| EFNA3 | ephrin-A3 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EMID1 | EMI domain containing 1 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO31 | F-box protein 31 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCC1 | GRIP and coiled-coil domain containing 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLI3 | GLI family zinc finger 3 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2BC | histone cluster 1, H2bc |
| HSPA2 | heat shock 70kDa protein 2 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| INO80D | INO80 complex subunit D |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KITLG | KIT ligand |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LOC730101 | uncharacterized LOC730101 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| METTL8 | methyltransferase like 8 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVP | major vault protein |
| MYL5 | myosin, light chain 5, regulatory |
| MYO19 | myosin XIX |
| NLGN1 | neuroligin 1 |
| NOL12 | nucleolar protein 12 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCDHA5 | protocadherin alpha 5 |
| PDE12 | phosphodiesterase 12 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| QSER1 | glutamine and serine rich 1 |
| RAPSN | receptor-associated protein of the synapse |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| REEP1 | receptor accessory protein 1 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS20 | regulator of G-protein signaling 20 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLC22A14 | solute carrier family 22, member 14 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TMEM212 | transmembrane protein 212 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VAX2 | ventral anterior homeobox 2 |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF324 | zinc finger protein 324 |
| ZNF668 | zinc finger protein 668 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
