| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the metergoline-5344 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIM2 | absent in melanoma 2 |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CEP164 | centrosomal protein 164kDa |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHKB | choline kinase beta |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CTBP2 | C-terminal binding protein 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP4 | dual specificity phosphatase 4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGR1 | early growth response 1 |
| FAM46C | family with sequence similarity 46, member C |
| FMOD | fibromodulin |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| HABP4 | hyaluronan binding protein 4 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HRK | harakiri, BCL2 interacting protein |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| INHBA | inhibin, beta A |
| INSIG1 | insulin induced gene 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIF13B | kinesin family member 13B |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LYST | lysosomal trafficking regulator |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP4 | microtubule-associated protein 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MMP19 | matrix metallopeptidase 19 |
| MON2 | MON2 homolog (S. cerevisiae) |
| MZF1 | myeloid zinc finger 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NRG2 | neuregulin 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PC | pyruvate carboxylase |
| PDCD6 | programmed cell death 6 |
| PDE8B | phosphodiesterase 8B |
| PER1 | period circadian clock 1 |
| PLA2G3 | phospholipase A2, group III |
| PLCG1 | phospholipase C, gamma 1 |
| PLEC | plectin |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RBPMS | RNA binding protein with multiple splicing |
| RNF43 | ring finger protein 43 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SFXN3 | sideroflexin 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STX1A | syntaxin 1A (brain) |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TMEM62 | transmembrane protein 62 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TROVE2 | TROVE domain family, member 2 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| VASH2 | vasohibin 2 |
| VPS9D1 | VPS9 domain containing 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF446 | zinc finger protein 446 |
| ZNF532 | zinc finger protein 532 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ACYP2 | acylphosphatase 2, muscle type |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| BAG2 | BCL2-associated athanogene 2 |
| BCAS4 | breast carcinoma amplified sequence 4 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C1ORF216 | chromosome 1 open reading frame 216 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASD1 | CAS1 domain containing 1 |
| CBR4 | carbonyl reductase 4 |
| CDC37 | cell division cycle 37 |
| CENPQ | centromere protein Q |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| COCH | cochlin |
| CTSV | cathepsin V |
| DBR1 | debranching RNA lariats 1 |
| DCPS | decapping enzyme, scavenger |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DTWD1 | DTW domain containing 1 |
| DUSP12 | dual specificity phosphatase 12 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERH | enhancer of rudimentary homolog (Drosophila) |
| EVPL | envoplakin |
| EXOSC9 | exosome component 9 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FEM1C | fem-1 homolog c (C. elegans) |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GTF2I | general transcription factor IIi |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| GTPBP6 | GTP binding protein 6 (putative) |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| IFI6 | interferon, alpha-inducible protein 6 |
| JMJD1C | jumonji domain containing 1C |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| LACTB2 | lactamase, beta 2 |
| LIAS | lipoic acid synthetase |
| LMNB1 | lamin B1 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC730101 | uncharacterized LOC730101 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEIS1 | Meis homeobox 1 |
| METTL16 | methyltransferase like 16 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MRPL19 | mitochondrial ribosomal protein L19 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCID2 | PCI domain containing 2 |
| PCTP | phosphatidylcholine transfer protein |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PKN1 | protein kinase N1 |
| POLR3F | polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa |
| PP14571 | uncharacterized LOC100130449 |
| PPAN | peter pan homolog (Drosophila) |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RARS | arginyl-tRNA synthetase |
| RASA2 | RAS p21 protein activator 2 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RPL39L | ribosomal protein L39-like |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SACS | sacsin molecular chaperone |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC35A5 | solute carrier family 35, member A5 |
| SLC35F5 | solute carrier family 35, member F5 |
| SPIDR | scaffolding protein involved in DNA repair |
| STK16 | serine/threonine kinase 16 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TMEM38B | transmembrane protein 38B |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN1 | tetraspanin 1 |
| TXLNG | taxilin gamma |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) |
| WDR3 | WD repeat domain 3 |
| ZNF124 | zinc finger protein 124 |
| ZNF675 | zinc finger protein 675 |
| ZNF787 | zinc finger protein 787 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
