metergoline-6744 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the metergoline-6744 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AIM1L absent in melanoma 1-like
AQP3 aquaporin 3 (Gill blood group)
ARL14 ADP-ribosylation factor-like 14
ARTN artemin
ATF6B activating transcription factor 6 beta
ATF7IP activating transcription factor 7 interacting protein
BMP8B bone morphogenetic protein 8b
C10ORF12 chromosome 10 open reading frame 12
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
C9ORF156 chromosome 9 open reading frame 156
CCND2 cyclin D2
CD24 CD24 molecule
CD58 CD58 molecule
CDC42 cell division cycle 42
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCA2 chloride channel accessory 2
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CORO2B coronin, actin binding protein, 2B
CTH cystathionine gamma-lyase
CTSS cathepsin S
CXCR4 chemokine (C-X-C motif) receptor 4
CYBRD1 cytochrome b reductase 1
DHRS7 dehydrogenase/reductase (SDR family) member 7
EDIL3 EGF-like repeats and discoidin I-like domains 3
EFR3B EFR3 homolog B (S. cerevisiae)
EGR1 early growth response 1
ELOVL2 ELOVL fatty acid elongase 2
ELOVL5 ELOVL fatty acid elongase 5
FAM63A family with sequence similarity 63, member A
FAS Fas cell surface death receptor
FBXL18 F-box and leucine-rich repeat protein 18
FDPS farnesyl diphosphate synthase
FLOT1 flotillin 1
FMOD fibromodulin
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GALK2 galactokinase 2
GAS7 growth arrest-specific 7
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type
GK glycerol kinase
GUK1 guanylate kinase 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HDAC6 histone deacetylase 6
HEATR6 HEAT repeat containing 6
HIPK3 homeodomain interacting protein kinase 3
HPS1 Hermansky-Pudlak syndrome 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IGFBP1 insulin-like growth factor binding protein 1
IMPG2 interphotoreceptor matrix proteoglycan 2
INSIG1 insulin induced gene 1
KDM7A lysine (K)-specific demethylase 7A
KIAA0040 KIAA0040
KIAA0391 KIAA0391
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS8 lectin, galactoside-binding, soluble, 8
LHFPL2 lipoma HMGIC fusion partner-like 2
LIPG lipase, endothelial
LPIN1 lipin 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEF2D myocyte enhancer factor 2D
MMP10 matrix metallopeptidase 10
MRPS18C mitochondrial ribosomal protein S18C
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
MT1M metallothionein 1M
NOD1 nucleotide-binding oligomerization domain containing 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PRKCE protein kinase C, epsilon
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RGS12 regulator of G-protein signaling 12
RIN3 Ras and Rab interactor 3
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
S100A11 S100 calcium binding protein A11
SFTPB surfactant protein B
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SORT1 sortilin 1
SYT5 synaptotagmin V
TBXA2R thromboxane A2 receptor
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TMED7 transmembrane emp24 protein transport domain containing 7
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIL TLR4 interactor with leucine-rich repeats
TRIM29 tripartite motif containing 29
TRIM3 tripartite motif containing 3
TROVE2 TROVE domain family, member 2
USP22 ubiquitin specific peptidase 22
VGLL3 vestigial-like family member 3
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
ZFP30 ZFP30 zinc finger protein
ZNF76 zinc finger protein 76
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADAM23 ADAM metallopeptidase domain 23
ARMCX4 armadillo repeat containing, X-linked 4
ASAP1-IT1 ASAP1 intronic transcript 1
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BFSP1 beaded filament structural protein 1, filensin
C11ORF63 chromosome 11 open reading frame 63
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C1RL complement component 1, r subcomponent-like
C22ORF46 chromosome 22 open reading frame 46
C7ORF69 chromosome 7 open reading frame 69
CAPN15 calpain 15
CASS4 Cas scaffolding protein family member 4
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD3D CD3d molecule, delta (CD3-TCR complex)
CD79A CD79a molecule, immunoglobulin-associated alpha
CEP170B centrosomal protein 170B
CIDEC cell death-inducing DFFA-like effector c
CNN1 calponin 1, basic, smooth muscle
CPZ carboxypeptidase Z
CRMP1 collapsin response mediator protein 1
CRYBA2 crystallin, beta A2
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein)
DAGLA diacylglycerol lipase, alpha
DCLRE1A DNA cross-link repair 1A
DNM3 dynamin 3
FAM120C family with sequence similarity 120C
FBRS fibrosin
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMD8 FERM domain containing 8
FRS2 fibroblast growth factor receptor substrate 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GPR3 G protein-coupled receptor 3
GPRASP1 G protein-coupled receptor associated sorting protein 1
GREB1L growth regulation by estrogen in breast cancer-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC11 histone deacetylase 11
HOXA7 homeobox A7
HYI hydroxypyruvate isomerase (putative)
ICOS inducible T-cell co-stimulator
IFT140 intraflagellar transport 140
IRF2BP1 interferon regulatory factor 2 binding protein 1
ISYNA1 inositol-3-phosphate synthase 1
KCTD15 potassium channel tetramerization domain containing 15
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KRT4 keratin 4, type II
LAMC3 laminin, gamma 3
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LINC00597 long intergenic non-protein coding RNA 597
LOC100286895 cell division cycle 27 homolog pseudogene
LRP3 low density lipoprotein receptor-related protein 3
MAGEH1 melanoma antigen family H1
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MILR1 mast cell immunoglobulin-like receptor 1
MTSS1L metastasis suppressor 1-like
MUC3B mucin 3B, cell surface associated
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PDE8B phosphodiesterase 8B
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKD2L2 polycystic kidney disease 2-like 2
QSER1 glutamine and serine rich 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
SCIN scinderin
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD6 SET domain containing 6
SLC12A8 solute carrier family 12, member 8
SLC16A6 solute carrier family 16, member 6
SNTG1 syntrophin, gamma 1
SPRYD7 SPRY domain containing 7
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STEAP4 STEAP family member 4
STON1 stonin 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THBS3 thrombospondin 3
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TPCN1 two pore segment channel 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUBB2B tubulin, beta 2B class IIb
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VGF VGF nerve growth factor inducible
WDR62 WD repeat domain 62
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF358 zinc finger protein 358
ZNF549 zinc finger protein 549
ZNF778 zinc finger protein 778