| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the methazolamide-2733 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM7 | ADAM metallopeptidase domain 7 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ARHGAP28 | Rho GTPase activating protein 28 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BMP8A | bone morphogenetic protein 8a |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C6ORF10 | chromosome 6 open reading frame 10 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CALML3 | calmodulin-like 3 |
| CDHR2 | cadherin-related family member 2 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CENPB | centromere protein B, 80kDa |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CORO2B | coronin, actin binding protein, 2B |
| CST1 | cystatin SN |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| EBF2 | early B-cell factor 2 |
| EDDM3A | epididymal protein 3A |
| EGFR | epidermal growth factor receptor |
| EPHB2 | EPH receptor B2 |
| FAM106A | family with sequence similarity 106, member A |
| FAM13C | family with sequence similarity 13, member C |
| FGF6 | fibroblast growth factor 6 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLJ11292 | |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FLT4 | fms-related tyrosine kinase 4 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXA6 | homeobox A6 |
| HOXB3 | homeobox B3 |
| HPR | haptoglobin-related protein |
| HRK | harakiri, BCL2 interacting protein |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HTR7P1 | 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 |
| ICOS | inducible T-cell co-stimulator |
| IL12B | interleukin 12B |
| IL1RN | interleukin 1 receptor antagonist |
| IL33R | interleukin 33 receptor |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KRT81 | keratin 81, type II |
| KSR1 | kinase suppressor of ras 1 |
| LENEP | lens epithelial protein |
| LMF1 | lipase maturation factor 1 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MID1 | midline 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| NEK11 | NIMA-related kinase 11 |
| NLGN1 | neuroligin 1 |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRG1 | neuregulin 1 |
| PADI4 | peptidyl arginine deiminase, type IV |
| PAPOLB | poly(A) polymerase beta (testis specific) |
| PAX8 | paired box 8 |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PDLIM5 | PDZ and LIM domain 5 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLCH1 | phospholipase C, eta 1 |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| POU1F1 | POU class 1 homeobox 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRDM12 | PR domain containing 12 |
| PRKCA | protein kinase C, alpha |
| PRSS22 | protease, serine, 22 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RBM12B | RNA binding motif protein 12B |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RPLP2 | ribosomal protein, large, P2 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SEMG2 | semenogelin II |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIX3 | SIX homeobox 3 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMR3B | submaxillary gland androgen regulated protein 3B |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SPRR2B | small proline-rich protein 2B |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYT1 | synaptotagmin I |
| TJP3 | tight junction protein 3 |
| TLX2 | T-cell leukemia homeobox 2 |
| TMEM212 | transmembrane protein 212 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| XDH | xanthine dehydrogenase |
| ZNF235 | zinc finger protein 235 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AMT | aminomethyltransferase |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| APOLD1 | apolipoprotein L domain containing 1 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CARF | calcium responsive transcription factor |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC71 | coiled-coil domain containing 71 |
| CEP295 | centrosomal protein 295kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLGN | calmegin |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNNBL1 | catenin, beta like 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DUSP4 | dual specificity phosphatase 4 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FGL2 | fibrinogen-like 2 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FOXK2 | forkhead box K2 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GID4 | GID complex subunit 4 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0753 | KIAA0753 |
| KIAA1107 | KIAA1107 |
| KIF23 | kinesin family member 23 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LSP1 | lymphocyte-specific protein 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MYOZ3 | myozenin 3 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCALD | neurocalcin delta |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NINJ2 | ninjurin 2 |
| NOL10 | nucleolar protein 10 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PDZD7 | PDZ domain containing 7 |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIR | pirin (iron-binding nuclear protein) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLD3 | phospholipase D family, member 3 |
| PORCN | porcupine homolog (Drosophila) |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PTH2R | parathyroid hormone 2 receptor |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCG5 | secretogranin V |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERINC5 | serine incorporator 5 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SPAG1 | sperm associated antigen 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STX11 | syntaxin 11 |
| SYCP2 | synaptonemal complex protein 2 |
| TEC | tec protein tyrosine kinase |
| THBS3 | thrombospondin 3 |
| TMEM180 | transmembrane protein 180 |
| TMEM242 | transmembrane protein 242 |
| TMEM53 | transmembrane protein 53 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TWISTNB | TWIST neighbor |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| USP6 | ubiquitin specific peptidase 6 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WT1-AS | WT1 antisense RNA |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF219 | zinc finger protein 219 |
| ZNF225 | zinc finger protein 225 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |