| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the methazolamide-3474 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| AK2 | adenylate kinase 2 |
| ALMS1 | Alstrom syndrome protein 1 |
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARTN | artemin |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| B9D2 | B9 protein domain 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BCO1 | beta-carotene oxygenase 1 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD82 | CD82 molecule |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CDK19 | cyclin-dependent kinase 19 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CYTH1 | cytohesin 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DUSP10 | dual specificity phosphatase 10 |
| DVL2 | dishevelled segment polarity protein 2 |
| EGFR | epidermal growth factor receptor |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ERCC4 | excision repair cross-complementation group 4 |
| FBXL18 | F-box and leucine-rich repeat protein 18 |
| FOXP3 | forkhead box P3 |
| FRMD1 | FERM domain containing 1 |
| GAS7 | growth arrest-specific 7 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLRX3 | glutaredoxin 3 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GYG2 | glycogenin 2 |
| HFE | hemochromatosis |
| HMOX1 | heme oxygenase 1 |
| HOXC10 | homeobox C10 |
| HYI | hydroxypyruvate isomerase (putative) |
| IL6ST | interleukin 6 signal transducer |
| IRS2 | insulin receptor substrate 2 |
| ITGB6 | integrin, beta 6 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KRBOX4 | KRAB box domain containing 4 |
| KRT17 | keratin 17, type I |
| KRT85 | keratin 85, type II |
| LDB1 | LIM domain binding 1 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOC157562 | uncharacterized LOC157562 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| N4BP1 | NEDD4 binding protein 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NOL12 | nucleolar protein 12 |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| OLFML2A | olfactomedin-like 2A |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLIN2 | perilipin 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PSEN2 | presenilin 2 |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| RASAL2 | RAS protein activator like 2 |
| RER1 | retention in endoplasmic reticulum sorting receptor 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RNF2 | ring finger protein 2 |
| RPLP2 | ribosomal protein, large, P2 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SGPL1 | sphingosine-1-phosphate lyase 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRPR | signal recognition particle receptor (docking protein) |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STK11 | serine/threonine kinase 11 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMC6 | transmembrane channel-like 6 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TRIM16 | tripartite motif containing 16 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF202 | zinc finger protein 202 |
| ZNF350 | zinc finger protein 350 |
| ZNF41 | zinc finger protein 41 |
| ZNF652 | zinc finger protein 652 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ADM | adrenomedullin |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APOD | apolipoprotein D |
| ARL15 | ADP-ribosylation factor-like 15 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C5AR2 | complement component 5a receptor 2 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CD151 | CD151 molecule (Raph blood group) |
| CDK20 | cyclin-dependent kinase 20 |
| CDK3 | cyclin-dependent kinase 3 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHST10 | carbohydrate sulfotransferase 10 |
| CISH | cytokine inducible SH2-containing protein |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL9A2 | collagen, type IX, alpha 2 |
| CORT | cortistatin |
| CRLF1 | cytokine receptor-like factor 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNM1 | dynamin 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EHD3 | EH-domain containing 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM169A | family with sequence similarity 169, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| IFT81 | intraflagellar transport 81 |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IRF1 | interferon regulatory factor 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0319L | KIAA0319-like |
| KIAA0355 | KIAA0355 |
| KLHL21 | kelch-like family member 21 |
| LAMA5 | laminin, alpha 5 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| LYRM9 | LYR motif containing 9 |
| MAMLD1 | mastermind-like domain containing 1 |
| MAP9 | microtubule-associated protein 9 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MFAP2 | microfibrillar-associated protein 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| PARPBP | PARP1 binding protein |
| PLA2G3 | phospholipase A2, group III |
| PMCH | pro-melanin-concentrating hormone |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRPH | peripherin |
| PRR7 | proline rich 7 (synaptic) |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RNF123 | ring finger protein 123 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RWDD3 | RWD domain containing 3 |
| SAV1 | salvador family WW domain containing protein 1 |
| SDF2 | stromal cell-derived factor 2 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC41A3 | solute carrier family 41, member 3 |
| SPATA2L | spermatogenesis associated 2-like |
| SREK1IP1 | SREK1-interacting protein 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM104 | transmembrane protein 104 |
| TMEM115 | transmembrane protein 115 |
| TOM1 | target of myb1 (chicken) |
| TRIM25 | tripartite motif containing 25 |
| TTBK2 | tau tubulin kinase 2 |
| TTC26 | tetratricopeptide repeat domain 26 |
| TUBA3C | tubulin, alpha 3c |
| WBP2 | WW domain binding protein 2 |
| XAB2 | XPA binding protein 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF480 | zinc finger protein 480 |
| ZNF668 | zinc finger protein 668 |
