| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the methazolamide-5794 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADCY9 | adenylate cyclase 9 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| AFF1 | AF4/FMR2 family, member 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALPK1 | alpha-kinase 1 |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BMP7 | bone morphogenetic protein 7 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CCDC132 | coiled-coil domain containing 132 |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CD80 | CD80 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CLEC4A | C-type lectin domain family 4, member A |
| CORO2B | coronin, actin binding protein, 2B |
| CRAT | carnitine O-acetyltransferase |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| CYTH4 | cytohesin 4 |
| DCT | dopachrome tautomerase |
| DFNB31 | deafness, autosomal recessive 31 |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DIO2 | deiodinase, iodothyronine, type II |
| DKFZP434C153 | DKFZP434C153 protein |
| DOCK5 | dedicator of cytokinesis 5 |
| FCAR | Fc fragment of IgA receptor |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GIPC2 | GIPC PDZ domain containing family, member 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GP6 | glycoprotein VI (platelet) |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM7 | glutamate receptor, metabotropic 7 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGL | immunoglobulin lambda locus |
| ING2 | inhibitor of growth family, member 2 |
| ING4 | inhibitor of growth family, member 4 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIF1A | kinesin family member 1A |
| KRT32 | keratin 32, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC100127972 | uncharacterized LOC100127972 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 |
| MMP25 | matrix metallopeptidase 25 |
| NGDN | neuroguidin, EIF4E binding protein |
| NOP16 | NOP16 nucleolar protein |
| NPY2R | neuropeptide Y receptor Y2 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NUP54 | nucleoporin 54kDa |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARVA | parvin, alpha |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHOX2A | paired-like homeobox 2a |
| PIWIL2 | piwi-like RNA-mediated gene silencing 2 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| POU5F1B | POU class 5 homeobox 1B |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PVRIG | poliovirus receptor related immunoglobulin domain containing |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RIF1 | replication timing regulatory factor 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RPL35A | ribosomal protein L35a |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| RUNX1 | runt-related transcription factor 1 |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SKIL | SKI-like proto-oncogene |
| SLA | Src-like-adaptor |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SRP72 | signal recognition particle 72kDa |
| STK24 | serine/threonine kinase 24 |
| SYT12 | synaptotagmin XII |
| TACR1 | tachykinin receptor 1 |
| TFR2 | transferrin receptor 2 |
| TLR6 | toll-like receptor 6 |
| TNN | tenascin N |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| USP2 | ubiquitin specific peptidase 2 |
| VPRBP | Vpr (HIV-1) binding protein |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| ZNF224 | zinc finger protein 224 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| AGO4 | argonaute RISC catalytic component 4 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BEND5 | BEN domain containing 5 |
| BTC | betacellulin |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1RL | complement component 1, r subcomponent-like |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDN | dendrin |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DUSP8 | dual specificity phosphatase 8 |
| ECM1 | extracellular matrix protein 1 |
| EGR2 | early growth response 2 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FMO4 | flavin containing monooxygenase 4 |
| FMOD | fibromodulin |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GLB1L | galactosidase, beta 1-like |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4D | histone cluster 1, H4d |
| HLX | H2.0-like homeobox |
| HOXC11 | homeobox C11 |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI44L | interferon-induced protein 44-like |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL11RA | interleukin 11 receptor, alpha |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLHL28 | kelch-like family member 28 |
| LMNB1 | lamin B1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MED15 | mediator complex subunit 15 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MMP3 | matrix metallopeptidase 3 |
| MMRN2 | multimerin 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYO1F | myosin IF |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NDRG4 | NDRG family member 4 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OLFML2A | olfactomedin-like 2A |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDH17 | protocadherin 17 |
| PDE8B | phosphodiesterase 8B |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| POMT1 | protein-O-mannosyltransferase 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRR15L | proline rich 15-like |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS22 | protease, serine, 22 |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB3A | RAB3A, member RAS oncogene family |
| RGS17 | regulator of G-protein signaling 17 |
| RNF39 | ring finger protein 39 |
| SETBP1 | SET binding protein 1 |
| SNPH | syntaphilin |
| SPRYD7 | SPRY domain containing 7 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STAG3 | stromal antigen 3 |
| TCTN1 | tectonic family member 1 |
| TENM4 | teneurin transmembrane protein 4 |
| TLR2 | toll-like receptor 2 |
| TMEM132A | transmembrane protein 132A |
| TRABD | TraB domain containing |
| TRAF2 | TNF receptor-associated factor 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA4B | tubulin, alpha 4b |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UGT8 | UDP glycosyltransferase 8 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF358 | zinc finger protein 358 |
| ZNF428 | zinc finger protein 428 |
| ZNF552 | zinc finger protein 552 |
| ZNF671 | zinc finger protein 671 |
