| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the methazolamide-6268 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACRV1 | acrosomal vesicle protein 1 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALPK1 | alpha-kinase 1 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| BAIAP3 | BAI1-associated protein 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CEP250 | centrosomal protein 250kDa |
| CHMP6 | charged multivesicular body protein 6 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EXPH5 | exophilin 5 |
| EZR | ezrin |
| FAM155A | family with sequence similarity 155, member A |
| FAM169A | family with sequence similarity 169, member A |
| FCMR | Fc fragment of IgM receptor |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGL1 | fibrinogen-like 1 |
| FH | fumarate hydratase |
| GLG1 | golgi glycoprotein 1 |
| GPR137 | G protein-coupled receptor 137 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GSPT2 | G1 to S phase transition 2 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HFE | hemochromatosis |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT140 | intraflagellar transport 140 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL16 | interleukin 16 |
| IRF9 | interferon regulatory factor 9 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGB4 | integrin, beta 4 |
| JUNB | jun B proto-oncogene |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMC2 | laminin, gamma 2 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LUZP1 | leucine zipper protein 1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MLX | MLX, MAX dimerization protein |
| MMRN2 | multimerin 2 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MPPE1 | metallophosphoesterase 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NOTCH2 | notch 2 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRMT7 | protein arginine methyltransferase 7 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RANBP1 | RAN binding protein 1 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RPL7 | ribosomal protein L7 |
| SFTPB | surfactant protein B |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMTN | smoothelin |
| SPPL2B | signal peptide peptidase like 2B |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| TCTN1 | tectonic family member 1 |
| TMEM121 | transmembrane protein 121 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TOP3A | topoisomerase (DNA) III alpha |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSPAN9 | tetraspanin 9 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 |
| UBOX5 | U-box domain containing 5 |
| USB1 | U6 snRNA biogenesis 1 |
| UTRN | utrophin |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF701 | zinc finger protein 701 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKRD10 | ankyrin repeat domain 10 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 |
| ATG2B | autophagy related 2B |
| ATP11B | ATPase, class VI, type 11B |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CAPN15 | calpain 15 |
| CBR4 | carbonyl reductase 4 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC88C | coiled-coil domain containing 88C |
| CEP72 | centrosomal protein 72kDa |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CROT | carnitine O-octanoyltransferase |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DAZAP1 | DAZ associated protein 1 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| DTWD1 | DTW domain containing 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| F8 | coagulation factor VIII, procoagulant component |
| FASTKD5 | FAST kinase domains 5 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| GATA6 | GATA binding protein 6 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLCE | glucuronic acid epimerase |
| GMIP | GEM interacting protein |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AC | histone cluster 1, H2ac |
| HOOK1 | hook microtubule-tethering protein 1 |
| IL17RA | interleukin 17 receptor A |
| IMPACT | impact RWD domain protein |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0125 | KIAA0125 |
| KIAA0922 | KIAA0922 |
| KIF18A | kinesin family member 18A |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGEF1 | melanoma antigen family F1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MED15 | mediator complex subunit 15 |
| MEIS1 | Meis homeobox 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NCAPH | non-SMC condensin I complex, subunit H |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARG | poly (ADP-ribose) glycohydrolase |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PKN1 | protein kinase N1 |
| PPL | periplakin |
| PQLC1 | PQ loop repeat containing 1 |
| PRR3 | proline rich 3 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBM38 | RNA binding motif protein 38 |
| RCOR3 | REST corepressor 3 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF25 | ring finger protein 25 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SH2D4A | SH2 domain containing 4A |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SNX6 | sorting nexin 6 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYT17 | synaptotagmin XVII |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TNRC6B | trinucleotide repeat containing 6B |
| TSPYL5 | TSPY-like 5 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WBP2 | WW domain binding protein 2 |
| WDR7 | WD repeat domain 7 |
| XYLT2 | xylosyltransferase II |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF23 | zinc finger protein 23 |
| ZNF280D | zinc finger protein 280D |
| ZNF408 | zinc finger protein 408 |
| ZNF552 | zinc finger protein 552 |
| ZNF787 | zinc finger protein 787 |
| ZXDC | ZXD family zinc finger C |
