methocarbamol-2111 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the methocarbamol-2111 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALOX12 arachidonate 12-lipoxygenase
ALPK1 alpha-kinase 1
ANXA10 annexin A10
APOM apolipoprotein M
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BCHE butyrylcholinesterase
C10ORF10 chromosome 10 open reading frame 10
C17ORF80 chromosome 17 open reading frame 80
C1QL1 complement component 1, q subcomponent-like 1
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CDK13 cyclin-dependent kinase 13
CLDN17 claudin 17
CLEC1A C-type lectin domain family 1, member A
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNOT4 CCR4-NOT transcription complex, subunit 4
CNTLN centlein, centrosomal protein
CREB5 cAMP responsive element binding protein 5
DBP D site of albumin promoter (albumin D-box) binding protein
DCAKD dephospho-CoA kinase domain containing
DCN decorin
ELSPBP1 epididymal sperm binding protein 1
ERAP1 endoplasmic reticulum aminopeptidase 1
ETV1 ets variant 1
FAM86C1 family with sequence similarity 86, member C1
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FAS Fas cell surface death receptor
FCMR Fc fragment of IgM receptor
FGL1 fibrinogen-like 1
FLJ11292
FXYD2 FXYD domain containing ion transport regulator 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HIST1H4D histone cluster 1, H4d
HOMER3 homer scaffolding protein 3
HOOK1 hook microtubule-tethering protein 1
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFT81 intraflagellar transport 81
JUN jun proto-oncogene
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF3A kinesin family member 3A
LRRC37A3 leucine rich repeat containing 37, member A3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
LYPD3 LY6/PLAUR domain containing 3
MBNL2 muscleblind-like splicing regulator 2
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MCL1 myeloid cell leukemia 1
MED1 mediator complex subunit 1
MLXIP MLX interacting protein
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NFIB nuclear factor I/B
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOL12 nucleolar protein 12
NR2F2 nuclear receptor subfamily 2, group F, member 2
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDE2A phosphodiesterase 2A, cGMP-stimulated
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
POM121L2 POM121 transmembrane nucleoporin-like 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRR14L proline rich 14-like
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRR protein tyrosine phosphatase, receptor type, R
RAB27B RAB27B, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RAD51B RAD51 paralog B
RERE arginine-glutamic acid dipeptide (RE) repeats
RPL23AP32 ribosomal protein L23a pseudogene 32
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
S100A13 S100 calcium binding protein A13
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SENP5 SUMO1/sentrin specific peptidase 5
SERHL2 serine hydrolase-like 2
SFTPB surfactant protein B
SND1-IT1 SND1 intronic transcript 1
STRA6 stimulated by retinoic acid 6
SUGP1 SURP and G patch domain containing 1
SYNE1 spectrin repeat containing, nuclear envelope 1
TCF4 transcription factor 4
TGFB3 transforming growth factor, beta 3
TMEM180 transmembrane protein 180
TNC tenascin C
TRAPPC13 trafficking protein particle complex 13
TRIM25 tripartite motif containing 25
TTC39A tetratricopeptide repeat domain 39A
URI1 URI1, prefoldin-like chaperone
USP27X ubiquitin specific peptidase 27, X-linked
VDAC3 voltage-dependent anion channel 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF385D zinc finger protein 385D
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD2B ATPase family, AAA domain containing 2B
ATF7IP2 activating transcription factor 7 interacting protein 2
BAK1 BCL2-antagonist/killer 1
BCAS3 breast carcinoma amplified sequence 3
BCCIP BRCA2 and CDKN1A interacting protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
C16ORF62 chromosome 16 open reading frame 62
CAPN5 calpain 5
CASKIN2 CASK interacting protein 2
CCDC176 coiled-coil domain containing 176
CENPC centromere protein C
CHKB choline kinase beta
CLDN8 claudin 8
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CTDNEP1 CTD nuclear envelope phosphatase 1
CXORF56 chromosome X open reading frame 56
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBR1 debranching RNA lariats 1
DGKD diacylglycerol kinase, delta 130kDa
DMBT1 deleted in malignant brain tumors 1
FAM102A family with sequence similarity 102, member A
FANCF Fanconi anemia, complementation group F
FKBP10 FK506 binding protein 10, 65 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
GID4 GID complex subunit 4
GJC1 gap junction protein, gamma 1, 45kDa
GLDC glycine dehydrogenase (decarboxylating)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPATCH2L G patch domain containing 2-like
GPR4 G protein-coupled receptor 4
HINFP histone H4 transcription factor
HIST1H2BI histone cluster 1, H2bi
HS1BP3 HCLS1 binding protein 3
HSF2BP heat shock transcription factor 2 binding protein
HYAL3 hyaluronoglucosaminidase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL17RA interleukin 17 receptor A
IRF2BP1 interferon regulatory factor 2 binding protein 1
JRKL JRK-like
KRT16 keratin 16, type I
KRT4 keratin 4, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LMNB2 lamin B2
LRRC8E leucine rich repeat containing 8 family, member E
LYPLA2P1 lysophospholipase II pseudogene 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MON1B MON1 secretory trafficking family member B
MPI mannose phosphate isomerase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MX1 MX dynamin-like GTPase 1
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUPL2 nucleoporin like 2
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRR7 proline rich 7 (synaptic)
PTPN9 protein tyrosine phosphatase, non-receptor type 9
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RANBP17 RAN binding protein 17
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RHOBTB1 Rho-related BTB domain containing 1
RNF121 ring finger protein 121
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
RWDD3 RWD domain containing 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC46A3 solute carrier family 46, member 3
SMA4 glucuronidase, beta pseudogene
SNAP29 synaptosomal-associated protein, 29kDa
SNHG3 small nucleolar RNA host gene 3
STK16 serine/threonine kinase 16
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM183A transmembrane protein 183A
TRAIP TRAF interacting protein
TRAPPC6A trafficking protein particle complex 6A
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
USB1 U6 snRNA biogenesis 1
ZBED8 zinc finger, BED-type containing 8
ZDHHC24 zinc finger, DHHC-type containing 24
ZNF324 zinc finger protein 324
ZNF611 zinc finger protein 611
ZSCAN5A zinc finger and SCAN domain containing 5A