methocarbamol-2274 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

197 genes differentially expressed following the methocarbamol-2274 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
AIM2 absent in melanoma 2
AKT2 v-akt murine thymoma viral oncogene homolog 2
AMBP alpha-1-microglobulin/bikunin precursor
ANKMY1 ankyrin repeat and MYND domain containing 1
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ATG10 autophagy related 10
BLNK B-cell linker
C1ORF54 chromosome 1 open reading frame 54
C5ORF42 chromosome 5 open reading frame 42
C7ORF69 chromosome 7 open reading frame 69
CADM4 cell adhesion molecule 4
CD4 CD4 molecule
CD70 CD70 molecule
CDRT1 CMT1A duplicated region transcript 1
CFAP69 cilia and flagella associated protein 69
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLEC4A C-type lectin domain family 4, member A
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CRH corticotropin releasing hormone
CSF1R colony stimulating factor 1 receptor
CSHL1 chorionic somatomammotropin hormone-like 1
CTIF CBP80/20-dependent translation initiation factor
CTSF cathepsin F
DEFA4 defensin, alpha 4, corticostatin
DLX2 distal-less homeobox 2
DRD2 dopamine receptor D2
DUSP1 dual specificity phosphatase 1
ERCC2 excision repair cross-complementation group 2
ETV7 ets variant 7
FGFR2 fibroblast growth factor receptor 2
GAS7 growth arrest-specific 7
GIPC2 GIPC PDZ domain containing family, member 2
GPR161 G protein-coupled receptor 161
GREB1L growth regulation by estrogen in breast cancer-like
GRM8 glutamate receptor, metabotropic 8
HEYL hes-related family bHLH transcription factor with YRPW motif-like
HFE hemochromatosis
HIST1H1T histone cluster 1, H1t
HLF hepatic leukemia factor
HP haptoglobin
IFT54 intraflagellar transport 54
IL1RN interleukin 1 receptor antagonist
ITGB7 integrin, beta 7
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LTBP4 latent transforming growth factor beta binding protein 4
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAOB monoamine oxidase B
MAP1A microtubule-associated protein 1A
MEF2D myocyte enhancer factor 2D
MMP24 matrix metallopeptidase 24 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MYO3A myosin IIIA
MYOG myogenin (myogenic factor 4)
MZF1 myeloid zinc finger 1
NCKIPSD NCK interacting protein with SH3 domain
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NEU3 sialidase 3 (membrane sialidase)
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOX3 NADPH oxidase 3
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
PARP3 poly (ADP-ribose) polymerase family, member 3
PCDH11X protocadherin 11 X-linked
PCSK2 proprotein convertase subtilisin/kexin type 2
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PRKG2 protein kinase, cGMP-dependent, type II
PTAFR platelet-activating factor receptor
PTCRA pre T-cell antigen receptor alpha
PTGDR2 prostaglandin D2 receptor 2
RAB11B RAB11B, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RAG2 recombination activating gene 2
RUNX1 runt-related transcription factor 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIRT5 sirtuin 5
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPP1 secreted phosphoprotein 1
TBX5 T-box 5
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEX15 testis expressed 15
TGM2 transglutaminase 2
TLR4 toll-like receptor 4
TM4SF5 transmembrane 4 L six family member 5
TMEM63A transmembrane protein 63A
TREX1 three prime repair exonuclease 1
TRIM38 tripartite motif containing 38
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC22D2 TSC22 domain family, member 2
WNT2 wingless-type MMTV integration site family member 2
XYLB xylulokinase homolog (H. influenzae)
ZNF362 zinc finger protein 362
ZNF506 zinc finger protein 506

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADTRP androgen-dependent TFPI-regulating protein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APLP1 amyloid beta (A4) precursor-like protein 1
ARRB1 arrestin, beta 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BBC3 BCL2 binding component 3
BRPF1 bromodomain and PHD finger containing, 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C9ORF9 chromosome 9 open reading frame 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALML5 calmodulin-like 5
CAPN15 calpain 15
CCDC132 coiled-coil domain containing 132
CLCF1 cardiotrophin-like cytokine factor 1
CLDN15 claudin 15
CLIP4 CAP-GLY domain containing linker protein family, member 4
CNTN1 contactin 1
CORO7 coronin 7
CRABP1 cellular retinoic acid binding protein 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHA2 EPH receptor A2
EXD3 exonuclease 3'-5' domain containing 3
FAM131A family with sequence similarity 131, member A
FBXL7 F-box and leucine-rich repeat protein 7
FOXI1 forkhead box I1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GFI1 growth factor independent 1 transcription repressor
GPR143 G protein-coupled receptor 143
GRAMD1C GRAM domain containing 1C
GRPR gastrin-releasing peptide receptor
GTPBP2 GTP binding protein 2
HIST1H2BC histone cluster 1, H2bc
HIST2H2AA3 histone cluster 2, H2aa3
HOOK1 hook microtubule-tethering protein 1
HOXC10 homeobox C10
HOXC8 homeobox C8
IQCG IQ motif containing G
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KREMEN2 kringle containing transmembrane protein 2
LOXL3 lysyl oxidase-like 3
LRRC20 leucine rich repeat containing 20
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MCOLN1 mucolipin 1
MFAP2 microfibrillar-associated protein 2
MSI1 musashi RNA-binding protein 1
NCALD neurocalcin delta
OSGIN1 oxidative stress induced growth inhibitor 1
OVOL1 ovo-like zinc finger 1
PLCD1 phospholipase C, delta 1
PRAMEF11 PRAME family member 11
PYCRL pyrroline-5-carboxylate reductase-like
PYHIN1 pyrin and HIN domain family, member 1
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF122 ring finger protein 122
RNF208 ring finger protein 208
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
S100A9 S100 calcium binding protein A9
SKI SKI proto-oncogene
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SND1-IT1 SND1 intronic transcript 1
STK16 serine/threonine kinase 16
STMN3 stathmin-like 3
STON1 stonin 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TFF2 trefoil factor 2
THBS3 thrombospondin 3
TLN1 talin 1
TRAIP TRAF interacting protein
TSNAXIP1 translin-associated factor X interacting protein 1
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
WDR91 WD repeat domain 91
YEATS2 YEATS domain containing 2
YY2 YY2 transcription factor
ZNF204P zinc finger protein 204, pseudogene
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350
ZNF532 zinc finger protein 532
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862