| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the methotrexate-1599 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALPK1 | alpha-kinase 1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARF3 | ADP-ribosylation factor 3 |
| ATP5SL | ATP5S-like |
| BCAN | brevican |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| C11ORF71 | chromosome 11 open reading frame 71 |
| CCNA1 | cyclin A1 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CETN1 | centrin, EF-hand protein, 1 |
| CTBP2 | C-terminal binding protein 2 |
| CYB561 | cytochrome b561 |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| GATA2 | GATA binding protein 2 |
| GCDH | glutaryl-CoA dehydrogenase |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRK6 | G protein-coupled receptor kinase 6 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HOXD1 | homeobox D1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IFITM3 | interferon induced transmembrane protein 3 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KYNU | kynureninase |
| LDB1 | LIM domain binding 1 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAGT1 | magnesium transporter 1 |
| MAP7D3 | MAP7 domain containing 3 |
| MICALL1 | MICAL-like 1 |
| MOB3B | MOB kinase activator 3B |
| MPZL1 | myelin protein zero-like 1 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| MYO1B | myosin IB |
| NADK | NAD kinase |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDRG3 | NDRG family member 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NUP205 | nucleoporin 205kDa |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFDN1 | prefoldin subunit 1 |
| POLI | polymerase (DNA directed) iota |
| PRR14L | proline rich 14-like |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RAD51D | RAD51 paralog D |
| RASL11B | RAS-like, family 11, member B |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBM12B | RNA binding motif protein 12B |
| REC8 | REC8 meiotic recombination protein |
| RIN1 | Ras and Rab interactor 1 |
| RNF121 | ring finger protein 121 |
| RNF144A | ring finger protein 144A |
| RWDD2B | RWD domain containing 2B |
| RWDD3 | RWD domain containing 3 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SETD4 | SET domain containing 4 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SNX17 | sorting nexin 17 |
| SOAT1 | sterol O-acyltransferase 1 |
| SPATA20 | spermatogenesis associated 20 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPN | sialophorin |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SRI | sorcin |
| SUGP1 | SURP and G patch domain containing 1 |
| SUOX | sulfite oxidase |
| SZRD1 | SUZ RNA binding domain containing 1 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TBC1D30 | TBC1 domain family, member 30 |
| THTPA | thiamine triphosphatase |
| TMEM159 | transmembrane protein 159 |
| TMEM161A | transmembrane protein 161A |
| TMEM246 | transmembrane protein 246 |
| TRD | T cell receptor delta locus |
| TRIM14 | tripartite motif containing 14 |
| TRMT61A | tRNA methyltransferase 61A |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| UNC45A | unc-45 homolog A (C. elegans) |
| YIPF2 | Yip1 domain family, member 2 |
| YLPM1 | YLP motif containing 1 |
| ZC3H14 | zinc finger CCCH-type containing 14 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF226 | zinc finger protein 226 |
| ZNF443 | zinc finger protein 443 |
| ZNF552 | zinc finger protein 552 |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANXA2P2 | annexin A2 pseudogene 2 |
| APOBR | apolipoprotein B receptor |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AURKB | aurora kinase B |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCOR | BCL6 corepressor |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C19ORF24 | chromosome 19 open reading frame 24 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CAPN15 | calpain 15 |
| CCNB1 | cyclin B1 |
| CDC20 | cell division cycle 20 |
| CDC37 | cell division cycle 37 |
| CDCA8 | cell division cycle associated 8 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPE | centromere protein E, 312kDa |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| DBF4 | DBF4 zinc finger |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DOLK | dolichol kinase |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EMC9 | ER membrane protein complex subunit 9 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FCHSD2 | FCH and double SH3 domains 2 |
| FMNL1 | formin-like 1 |
| H1FX | H1 histone family, member X |
| HAGH | hydroxyacylglutathione hydrolase |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H4C | histone cluster 1, H4c |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HN1 | hematological and neurological expressed 1 |
| ILK | integrin-linked kinase |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IRF2 | interferon regulatory factor 2 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIF11 | kinesin family member 11 |
| KIF20A | kinesin family member 20A |
| KIFC1 | kinesin family member C1 |
| LOC642236 | FSHD region gene 1 pseudogene |
| LOC729164 | hCG1732469 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MEPCE | methylphosphate capping enzyme |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| NCAPD2 | non-SMC condensin I complex, subunit D2 |
| NDC80 | NDC80 kinetochore complex component |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLK1 | polo-like kinase 1 |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RALY | RALY heterogeneous nuclear ribonucleoprotein |
| RBBP6 | retinoblastoma binding protein 6 |
| RNF103 | ring finger protein 103 |
| RNF11 | ring finger protein 11 |
| RNF122 | ring finger protein 122 |
| RNF220 | ring finger protein 220 |
| RRP1 | ribosomal RNA processing 1 |
| SCPEP1 | serine carboxypeptidase 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| SRRD | SRR1 domain containing |
| SSNA1 | Sjogren syndrome nuclear autoantigen 1 |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN2 | tectonic family member 2 |
| TMEM165 | transmembrane protein 165 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TUBB4B | tubulin, beta 4B class IVb |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP39 | ubiquitin specific peptidase 39 |
| WWC2 | WW and C2 domain containing 2 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
