| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the methotrexate-3214 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD2 | adducin 2 (beta) |
| AFF2 | AF4/FMR2 family, member 2 |
| AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BTG2 | BTG family, member 2 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC134 | coiled-coil domain containing 134 |
| CCPG1 | cell cycle progression 1 |
| CD1A | CD1a molecule |
| CD58 | CD58 molecule |
| CFHR4 | complement factor H-related 4 |
| CNTN5 | contactin 5 |
| COL5A1 | collagen, type V, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| DCN | decorin |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DSG3 | desmoglein 3 |
| EED | embryonic ectoderm development |
| EGR1 | early growth response 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| EXOSC1 | exosome component 1 |
| FAS | Fas cell surface death receptor |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FYB | FYN binding protein |
| GHRHR | growth hormone releasing hormone receptor |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR87 | G protein-coupled receptor 87 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HIST1H3E | histone cluster 1, H3e |
| IFT27 | intraflagellar transport 27 |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KIF24 | kinesin family member 24 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF13 | Kruppel-like factor 13 |
| KRT83 | keratin 83, type II |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LMF2 | lipase maturation factor 2 |
| LMNA | lamin A/C |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MR1 | major histocompatibility complex, class I-related |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MYOF | myoferlin |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NFIB | nuclear factor I/B |
| NOL12 | nucleolar protein 12 |
| NOX1 | NADPH oxidase 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PHF20 | PHD finger protein 20 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PSCA | prostate stem cell antigen |
| PTCRA | pre T-cell antigen receptor alpha |
| R3HDM1 | R3H domain containing 1 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RSU1 | Ras suppressor protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| S100A2 | S100 calcium binding protein A2 |
| S100A8 | S100 calcium binding protein A8 |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SEMG2 | semenogelin II |
| SESN1 | sestrin 1 |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SPRR1A | small proline-rich protein 1A |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SYT5 | synaptotagmin V |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TMOD1 | tropomodulin 1 |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TRIM10 | tripartite motif containing 10 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| UCN | urocortin |
| VCAN | versican |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF41 | zinc finger protein 41 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| AMD1 | adenosylmethionine decarboxylase 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AURKA | aurora kinase A |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP4 | bone morphogenetic protein 4 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCNB1 | cyclin B1 |
| CDC20 | cell division cycle 20 |
| CDCA8 | cell division cycle associated 8 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLSPN | claspin |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DBF4 | DBF4 zinc finger |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DOC2A | double C2-like domains, alpha |
| EMID1 | EMI domain containing 1 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM53B | family with sequence similarity 53, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GLI3 | GLI family zinc finger 3 |
| H1F0 | H1 histone family, member 0 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3G | histone cluster 1, H3g |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4F | histone cluster 1, H4f |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HOXC10 | homeobox C10 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| MAP6D1 | MAP6 domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MIR22HG | MIR22 host gene |
| MITF | microphthalmia-associated transcription factor |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| NDC80 | NDC80 kinetochore complex component |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEK11 | NIMA-related kinase 11 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PGP | phosphoglycolate phosphatase |
| PLK1 | polo-like kinase 1 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCAN3 | RCAN family member 3 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SPATA2L | spermatogenesis associated 2-like |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TCTN2 | tectonic family member 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM110 | transmembrane protein 110 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TPX2 | TPX2, microtubule-associated |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIP | TRAF interacting protein |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TROAP | trophinin associated protein |
| TXNIP | thioredoxin interacting protein |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP19 | ubiquitin specific peptidase 19 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP30 | ZFP30 zinc finger protein |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF34 | zinc finger protein 34 |
