| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the methoxamine-2848 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| AGRN | agrin |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOC1 | apolipoprotein C-I |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| ATXN2L | ataxin 2-like |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C2 | complement component 2 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CACYBP | calcyclin binding protein |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC68 | coiled-coil domain containing 68 |
| CDK3 | cyclin-dependent kinase 3 |
| CEP250 | centrosomal protein 250kDa |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CLEC11A | C-type lectin domain family 11, member A |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COL18A1 | collagen, type XVIII, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTSF | cathepsin F |
| CXXC1 | CXXC finger protein 1 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DUSP1 | dual specificity phosphatase 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EIF1 | eukaryotic translation initiation factor 1 |
| FAM110B | family with sequence similarity 110, member B |
| FFAR2 | free fatty acid receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FKRP | fukutin related protein |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GAB1 | GRB2-associated binding protein 1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HSF1 | heat shock transcription factor 1 |
| IDS | iduronate 2-sulfatase |
| INHBE | inhibin, beta E |
| ITGB4 | integrin, beta 4 |
| JAG2 | jagged 2 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KHK | ketohexokinase (fructokinase) |
| KYNU | kynureninase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NME5 | NME/NM23 family member 5 |
| PADI1 | peptidyl arginine deiminase, type I |
| PALM | paralemmin |
| PCDHB6 | protocadherin beta 6 |
| PFKL | phosphofructokinase, liver |
| PLEKHH3 | pleckstrin homology domain containing, family H (with MyTH4 domain) member 3 |
| POU3F2 | POU class 3 homeobox 2 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF43 | ring finger protein 43 |
| RUNX2 | runt-related transcription factor 2 |
| SCAP | SREBF chaperone |
| SH3BP2 | SH3-domain binding protein 2 |
| SIVA1 | SIVA1, apoptosis-inducing factor |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SOCS7 | suppressor of cytokine signaling 7 |
| STAC | SH3 and cysteine rich domain |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
| TBC1D30 | TBC1 domain family, member 30 |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TK2 | thymidine kinase 2, mitochondrial |
| TMC6 | transmembrane channel-like 6 |
| TMEM53 | transmembrane protein 53 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| YIPF2 | Yip1 domain family, member 2 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZFHX4 | zinc finger homeobox 4 |
| ZFPL1 | zinc finger protein-like 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF14 | zinc finger protein 14 |
| ZNF446 | zinc finger protein 446 |
| ZNF592 | zinc finger protein 592 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CA11 | carbonic anhydrase XI |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAPG | capping protein (actin filament), gelsolin-like |
| CDC42SE1 | CDC42 small effector 1 |
| CIC | capicua transcriptional repressor |
| CLGN | calmegin |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| CORT | cortistatin |
| CSTA | cystatin A (stefin A) |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DUSP2 | dual specificity phosphatase 2 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EPHA2 | EPH receptor A2 |
| FAM184A | family with sequence similarity 184, member A |
| FAM198B | family with sequence similarity 198, member B |
| FAM212B | family with sequence similarity 212, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF23 | fibroblast growth factor 23 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPR27 | G protein-coupled receptor 27 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BO | histone cluster 1, H2bo |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| JMJD4 | jumonji domain containing 4 |
| KLHL21 | kelch-like family member 21 |
| LPXN | leupaxin |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYRM9 | LYR motif containing 9 |
| MB | myoglobin |
| MCOLN1 | mucolipin 1 |
| MDM4 | MDM4, p53 regulator |
| MEFV | Mediterranean fever |
| NIPAL2 | NIPA-like domain containing 2 |
| NPTX1 | neuronal pentraxin I |
| NPY1R | neuropeptide Y receptor Y1 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHB3 | protocadherin beta 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POLH | polymerase (DNA directed), eta |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRR4 | proline rich 4 (lacrimal) |
| QSER1 | glutamine and serine rich 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB40C | RAB40C, member RAS oncogene family |
| RHOH | ras homolog family member H |
| RLN1 | relaxin 1 |
| RPL10L | ribosomal protein L10-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SETD1A | SET domain containing 1A |
| SIX1 | SIX homeobox 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SPON2 | spondin 2, extracellular matrix protein |
| SPRYD7 | SPRY domain containing 7 |
| ST5 | suppression of tumorigenicity 5 |
| STRN | striatin, calmodulin binding protein |
| SYNC | syncoilin, intermediate filament protein |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TLR5 | toll-like receptor 5 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRIM36 | tripartite motif containing 36 |
| TUBA3C | tubulin, alpha 3c |
| TWISTNB | TWIST neighbor |
| VGF | VGF nerve growth factor inducible |
| WDR33 | WD repeat domain 33 |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF136 | zinc finger protein 136 |
| ZNF141 | zinc finger protein 141 |
| ZNF34 | zinc finger protein 34 |