methoxsalen-3302 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the methoxsalen-3302 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP8L A kinase (PRKA) anchor protein 8-like
AKR1C1 aldo-keto reductase family 1, member C1
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGAP33 Rho GTPase activating protein 33
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF53 chromosome 17 open reading frame 53
CALD1 caldesmon 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD1A CD1a molecule
CDYL chromodomain protein, Y-like
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL11A1 collagen, type XI, alpha 1
CRMP1 collapsin response mediator protein 1
CYLD cylindromatosis (turban tumor syndrome)
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1
EFNB3 ephrin-B3
EVI5 ecotropic viral integration site 5
FAM212B family with sequence similarity 212, member B
FAM46C family with sequence similarity 46, member C
FANCA Fanconi anemia, complementation group A
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF6 fibroblast growth factor 6
FLOT1 flotillin 1
FN1 fibronectin 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GPER1 G protein-coupled estrogen receptor 1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HRH1 histamine receptor H1
IGHM immunoglobulin heavy constant mu
IRF5 interferon regulatory factor 5
KLHL25 kelch-like family member 25
LAMP1 lysosomal-associated membrane protein 1
MAPK8 mitogen-activated protein kinase 8
MECR mitochondrial trans-2-enoyl-CoA reductase
MFAP3L microfibrillar-associated protein 3-like
MORN1 MORN repeat containing 1
N4BP3 NEDD4 binding protein 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPM3 nucleophosmin/nucleoplasmin 3
NUP188 nucleoporin 188kDa
OGFR opioid growth factor receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH7 protocadherin 7
PCM1 pericentriolar material 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAGL1 pleiomorphic adenoma gene-like 1
PLCD1 phospholipase C, delta 1
PLXNC1 plexin C1
PPT2 palmitoyl-protein thioesterase 2
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PVRIG poliovirus receptor related immunoglobulin domain containing
PYHIN1 pyrin and HIN domain family, member 1
RAB6B RAB6B, member RAS oncogene family
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RBFA ribosome binding factor A (putative)
RBM5 RNA binding motif protein 5
RGS14 regulator of G-protein signaling 14
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RNF6 ring finger protein (C3H2C3 type) 6
RPL5 ribosomal protein L5
RRBP1 ribosome binding protein 1
RXRB retinoid X receptor, beta
S100A11 S100 calcium binding protein A11
SCN10A sodium channel, voltage gated, type X alpha subunit
SCRN3 secernin 3
SIVA1 SIVA1, apoptosis-inducing factor
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNX13 sorting nexin 13
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRCAP Snf2-related CREBBP activator protein
SSH3 slingshot protein phosphatase 3
STK17A serine/threonine kinase 17a
SULT4A1 sulfotransferase family 4A, member 1
TAPBP TAP binding protein (tapasin)
TBRG4 transforming growth factor beta regulator 4
TCEAL2 transcription elongation factor A (SII)-like 2
THBS4 thrombospondin 4
TLDC1 TBC/LysM-associated domain containing 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNNT3 troponin T type 3 (skeletal, fast)
TRAIP TRAF interacting protein
TYRP1 tyrosinase-related protein 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIPR2 vasoactive intestinal peptide receptor 2
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF277 zinc finger protein 277
ZNF358 zinc finger protein 358
ZNF609 zinc finger protein 609
ZNF76 zinc finger protein 76
ZNF770 zinc finger protein 770

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACTL8 actin-like 8
ALPK1 alpha-kinase 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMCX2 armadillo repeat containing, X-linked 2
BCL9 B-cell CLL/lymphoma 9
C8ORF44 chromosome 8 open reading frame 44
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPO centromere protein O
CERS4 ceramide synthase 4
CIC capicua transcriptional repressor
CORT cortistatin
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSTA cystatin A (stefin A)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DEAF1 DEAF1 transcription factor
DIXDC1 DIX domain containing 1
DMTN dematin actin binding protein
DPY19L1P1 DPY19L1 pseudogene 1
EFHD2 EF-hand domain family, member D2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERCC4 excision repair cross-complementation group 4
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
FADS2 fatty acid desaturase 2
FAM169A family with sequence similarity 169, member A
FBXL7 F-box and leucine-rich repeat protein 7
FLCN folliculin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
HOXC5 homeobox C5
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
IL4R interleukin 4 receptor
INCENP inner centromere protein antigens 135/155kDa
IRF6 interferon regulatory factor 6
ITPKB inositol-trisphosphate 3-kinase B
KLHL36 kelch-like family member 36
KREMEN2 kringle containing transmembrane protein 2
LHX6 LIM homeobox 6
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LTC4S leukotriene C4 synthase
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MMP2 matrix metallopeptidase 2
MSI1 musashi RNA-binding protein 1
NEK11 NIMA-related kinase 11
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRTN neurturin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI1 peptidyl arginine deiminase, type I
PCDHA6 protocadherin alpha 6
PCSK7 proprotein convertase subtilisin/kexin type 7
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
POMT2 protein-O-mannosyltransferase 2
RNF121 ring finger protein 121
RNF2 ring finger protein 2
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCN1B sodium channel, voltage gated, type I beta subunit
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TEP1 telomerase-associated protein 1
TLR2 toll-like receptor 2
TMEM180 transmembrane protein 180
TRABD TraB domain containing
TRIM16 tripartite motif containing 16
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VASH2 vasohibin 2
VEGFC vascular endothelial growth factor C
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFP37 ZFP37 zinc finger protein
ZIC3 Zic family member 3
ZNF205 zinc finger protein 205
ZNF532 zinc finger protein 532
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF747 zinc finger protein 747