methoxsalen-6661 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the methoxsalen-6661 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
AHSG alpha-2-HS-glycoprotein
APOH apolipoprotein H (beta-2-glycoprotein I)
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BMP10 bone morphogenetic protein 10
BMP2 bone morphogenetic protein 2
BMPR1B bone morphogenetic protein receptor, type IB
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CACFD1 calcium channel flower domain containing 1
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC134 coiled-coil domain containing 134
CCKAR cholecystokinin A receptor
CD2 CD2 molecule
CD247 CD247 molecule
CD4 CD4 molecule
CFAP70 cilia and flagella associated protein 70
CFLAR CASP8 and FADD-like apoptosis regulator
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CPB1 carboxypeptidase B1 (tissue)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DCAF15 DDB1 and CUL4 associated factor 15
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
FAM134B family with sequence similarity 134, member B
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FETUB fetuin B
FGF4 fibroblast growth factor 4
FOLR1 folate receptor 1 (adult)
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GLB1L2 galactosidase, beta 1-like 2
GLRX3 glutaredoxin 3
GRM2 glutamate receptor, metabotropic 2
GRM6 glutamate receptor, metabotropic 6
GTPBP1 GTP binding protein 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IFFO1 intermediate filament family orphan 1
IFNA17 interferon, alpha 17
IL18RAP interleukin 18 receptor accessory protein
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KLK11 kallikrein-related peptidase 11
KRT31 keratin 31, type I
LBX1 ladybird homeobox 1
LOC100131510 uncharacterized LOC100131510
LOC100131532 uncharacterized LOC100131532
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAGEA5 melanoma antigen family A5
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MTMR7 myotubularin related protein 7
MYOZ3 myozenin 3
NEU3 sialidase 3 (membrane sialidase)
NIPAL3 NIPA-like domain containing 3
OLFM4 olfactomedin 4
PBX2 pre-B-cell leukemia homeobox 2
PDCD6 programmed cell death 6
PHF7 PHD finger protein 7
PHOX2B paired-like homeobox 2b
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKD2L2 polycystic kidney disease 2-like 2
PLA2G5 phospholipase A2, group V
POU1F1 POU class 1 homeobox 1
PRKCE protein kinase C, epsilon
PRM1 protamine 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTTG2 pituitary tumor-transforming 2
RAB3D RAB3D, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNGTT RNA guanylyltransferase and 5'-phosphatase
RRAD Ras-related associated with diabetes
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SPARCL1 SPARC-like 1 (hevin)
SSX3 synovial sarcoma, X breakpoint 3
TBRG4 transforming growth factor beta regulator 4
TBX5 T-box 5
TEX14 testis expressed 14
TFR2 transferrin receptor 2
TJP3 tight junction protein 3
TMEM63A transmembrane protein 63A
TOP3B topoisomerase (DNA) III beta
TREM1 triggering receptor expressed on myeloid cells 1
TRIM10 tripartite motif containing 10
UHRF1BP1L UHRF1 binding protein 1-like
VGLL3 vestigial-like family member 3
ZNF208 zinc finger protein 208
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AFF4 AF4/FMR2 family, member 4
ARRB2 arrestin, beta 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BBC3 BCL2 binding component 3
BIRC3 baculoviral IAP repeat containing 3
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF63 chromosome 11 open reading frame 63
C14ORF105 chromosome 14 open reading frame 105
C1ORF56 chromosome 1 open reading frame 56
C3 complement component 3
C5ORF42 chromosome 5 open reading frame 42
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC85C coiled-coil domain containing 85C
CCL27 chemokine (C-C motif) ligand 27
CFAP69 cilia and flagella associated protein 69
CNGB3 cyclic nucleotide gated channel beta 3
CPEB1 cytoplasmic polyadenylation element binding protein 1
CPNE7 copine VII
CTC1 CTS telomere maintenance complex component 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNM3 dynamin 3
EDIL3 EGF-like repeats and discoidin I-like domains 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM204A family with sequence similarity 204, member A
FMO4 flavin containing monooxygenase 4
FOXN2 forkhead box N2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GEMIN8 gem (nuclear organelle) associated protein 8
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H4E histone cluster 1, H4e
HOOK1 hook microtubule-tethering protein 1
HOXA1 homeobox A1
IL4R interleukin 4 receptor
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0319L KIAA0319-like
KLF3 Kruppel-like factor 3 (basic)
LMNB1 lamin B1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MED15 mediator complex subunit 15
MEFV Mediterranean fever
MOCS3 molybdenum cofactor synthesis 3
MOXD1 monooxygenase, DBH-like 1
MRPL52 mitochondrial ribosomal protein L52
MTERF4 mitochondrial transcription termination factor 4
MX1 MX dynamin-like GTPase 1
MYO1F myosin IF
NOL12 nucleolar protein 12
NYNRIN NYN domain and retroviral integrase containing
ORAI3 ORAI calcium release-activated calcium modulator 3
P3H2 prolyl 3-hydroxylase 2
PELP1 proline, glutamate and leucine rich protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA1A phospholipase A1 member A
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PODXL2 podocalyxin-like 2
POMT2 protein-O-mannosyltransferase 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRE protein tyrosine phosphatase, receptor type, E
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB40A RAB40A, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM38 RNA binding motif protein 38
RCOR3 REST corepressor 3
RGCC regulator of cell cycle
RIBC2 RIB43A domain with coiled-coils 2
RPH3A rabphilin 3A
RUSC2 RUN and SH3 domain containing 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETBP1 SET binding protein 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPATA1 spermatogenesis associated 1
STARD5 StAR-related lipid transfer (START) domain containing 5
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYNPO synaptopodin
TAGLN transgelin
TEX40 testis expressed 40
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMSB15A thymosin beta 15a
TRABD TraB domain containing
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
VGF VGF nerve growth factor inducible
VN1R1 vomeronasal 1 receptor 1
ZBED8 zinc finger, BED-type containing 8
ZNF205 zinc finger protein 205
ZNF408 zinc finger protein 408
ZNF428 zinc finger protein 428
ZNF528 zinc finger protein 528
ZNF768 zinc finger protein 768