Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the methylbenzethonium chloride-2190 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADAM28 | ADAM metallopeptidase domain 28 |
ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
APC | adenomatous polyposis coli |
APOE | apolipoprotein E |
ATP13A2 | ATPase type 13A2 |
BIN1 | bridging integrator 1 |
BIRC3 | baculoviral IAP repeat containing 3 |
CCNG2 | cyclin G2 |
CCSER2 | coiled-coil serine-rich protein 2 |
CDC25C | cell division cycle 25C |
CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
CFAP45 | cilia and flagella associated protein 45 |
CFAP74 | cilia and flagella associated protein 74 |
CHPF | chondroitin polymerizing factor |
COL10A1 | collagen, type X, alpha 1 |
COL4A2 | collagen, type IV, alpha 2 |
COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
CSNK1G1 | casein kinase 1, gamma 1 |
CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
CUL7 | cullin 7 |
CYLD | cylindromatosis (turban tumor syndrome) |
CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
DCTN2 | dynactin 2 (p50) |
DLX2 | distal-less homeobox 2 |
DOPEY2 | dopey family member 2 |
ERBB2 | erb-b2 receptor tyrosine kinase 2 |
F11R | F11 receptor |
FAM120C | family with sequence similarity 120C |
FAM76A | family with sequence similarity 76, member A |
FGF23 | fibroblast growth factor 23 |
FLJ11292 | |
FLOT1 | flotillin 1 |
FMO5 | flavin containing monooxygenase 5 |
GLE1 | GLE1 RNA export mediator |
GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
HDAC11 | histone deacetylase 11 |
HIST1H1D | histone cluster 1, H1d |
HOXA1 | homeobox A1 |
HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
IL3RA | interleukin 3 receptor, alpha (low affinity) |
INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
IQSEC1 | IQ motif and Sec7 domain 1 |
JAK2 | Janus kinase 2 |
KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
KIAA1024 | KIAA1024 |
LCMT2 | leucine carboxyl methyltransferase 2 |
LMF2 | lipase maturation factor 2 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MAU2 | MAU2 sister chromatid cohesion factor |
MDFI | MyoD family inhibitor |
MT1G | metallothionein 1G |
MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
MUM1 | melanoma associated antigen (mutated) 1 |
N4BP2L1 | NEDD4 binding protein 2-like 1 |
NEK2 | NIMA-related kinase 2 |
NOP16 | NOP16 nucleolar protein |
NOV | nephroblastoma overexpressed |
NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
PAPPA2 | pappalysin 2 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PLD1 | phospholipase D1, phosphatidylcholine-specific |
POU6F1 | POU class 6 homeobox 1 |
PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
PTGIS | prostaglandin I2 (prostacyclin) synthase |
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
RANBP17 | RAN binding protein 17 |
RANBP3 | RAN binding protein 3 |
RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
RB1 | retinoblastoma 1 |
RHEB | Ras homolog enriched in brain |
RUFY3 | RUN and FYVE domain containing 3 |
SBNO2 | strawberry notch homolog 2 (Drosophila) |
SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
SELPLG | selectin P ligand |
SIT1 | signaling threshold regulating transmembrane adaptor 1 |
SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
SMAD3 | SMAD family member 3 |
SPG20 | spastic paraplegia 20 (Troyer syndrome) |
SPTB | spectrin, beta, erythrocytic |
SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
STK11 | serine/threonine kinase 11 |
TAAR5 | trace amine associated receptor 5 |
TAZ | tafazzin |
TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
TMEM140 | transmembrane protein 140 |
TMEM254 | transmembrane protein 254 |
TSKS | testis-specific serine kinase substrate |
UBE2I | ubiquitin-conjugating enzyme E2I |
UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
WRAP53 | WD repeat containing, antisense to TP53 |
ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
ZNF428 | zinc finger protein 428 |
ZNF609 | zinc finger protein 609 |
ZNF747 | zinc finger protein 747 |
Symbol | Name |
---|---|
ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
ACPP | acid phosphatase, prostate |
ADM | adrenomedullin |
ADORA3 | adenosine A3 receptor |
ALS2CL | ALS2 C-terminal like |
ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
ATF3 | activating transcription factor 3 |
BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
BHLHE41 | basic helix-loop-helix family, member e41 |
BIK | BCL2-interacting killer (apoptosis-inducing) |
C16ORF59 | chromosome 16 open reading frame 59 |
C5ORF45 | chromosome 5 open reading frame 45 |
CCDC132 | coiled-coil domain containing 132 |
CCDC71 | coiled-coil domain containing 71 |
CCDC85C | coiled-coil domain containing 85C |
CD1D | CD1d molecule |
CD300C | CD300c molecule |
CD320 | CD320 molecule |
CD34 | CD34 molecule |
CD69 | CD69 molecule |
CDKL3 | cyclin-dependent kinase-like 3 |
CEP170B | centrosomal protein 170B |
CFP | complement factor properdin |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CHMP6 | charged multivesicular body protein 6 |
CHST10 | carbohydrate sulfotransferase 10 |
CIDEC | cell death-inducing DFFA-like effector c |
CLCN2 | chloride channel, voltage-sensitive 2 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
DDIT4 | DNA-damage-inducible transcript 4 |
DDN | dendrin |
DGKG | diacylglycerol kinase, gamma 90kDa |
DOK3 | docking protein 3 |
DUSP8 | dual specificity phosphatase 8 |
EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
EFNA3 | ephrin-A3 |
ELP6 | elongator acetyltransferase complex subunit 6 |
ENO2 | enolase 2 (gamma, neuronal) |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
FRMD1 | FERM domain containing 1 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GPR27 | G protein-coupled receptor 27 |
GRPR | gastrin-releasing peptide receptor |
GTF2IRD1 | GTF2I repeat domain containing 1 |
HCAR3 | hydroxycarboxylic acid receptor 3 |
HILPDA | hypoxia inducible lipid droplet-associated |
HIST1H1T | histone cluster 1, H1t |
IL22 | interleukin 22 |
KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
KRT8P12 | keratin 8 pseudogene 12 |
LIMS2 | LIM and senescent cell antigen-like domains 2 |
MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
MMP9 | matrix metallopeptidase 9 |
NBEA | neurobeachin |
NDRG1 | N-myc downstream regulated 1 |
NIPAL2 | NIPA-like domain containing 2 |
NPFFR1 | neuropeptide FF receptor 1 |
NUPR1 | nuclear protein, transcriptional regulator, 1 |
OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
PADI2 | peptidyl arginine deiminase, type II |
PDZD7 | PDZ domain containing 7 |
PECR | peroxisomal trans-2-enoyl-CoA reductase |
PER3 | period circadian clock 3 |
PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
PHC1 | polyhomeotic homolog 1 (Drosophila) |
PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
PLCD1 | phospholipase C, delta 1 |
PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
PLTP | phospholipid transfer protein |
POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
RAB3A | RAB3A, member RAS oncogene family |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RGS13 | regulator of G-protein signaling 13 |
RGS16 | regulator of G-protein signaling 16 |
RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
RPAP1 | RNA polymerase II associated protein 1 |
S1PR4 | sphingosine-1-phosphate receptor 4 |
SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
TAGLN | transgelin |
TGFBR3 | transforming growth factor, beta receptor III |
TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
TIMP2 | TIMP metallopeptidase inhibitor 2 |
TMEM158 | transmembrane protein 158 (gene/pseudogene) |
TRAF2 | TNF receptor-associated factor 2 |
TSC22D4 | TSC22 domain family, member 4 |
USB1 | U6 snRNA biogenesis 1 |
VN1R1 | vomeronasal 1 receptor 1 |
WASF3 | WAS protein family, member 3 |
WNT10B | wingless-type MMTV integration site family, member 10B |
ZNF395 | zinc finger protein 395 |
ZSCAN5A | zinc finger and SCAN domain containing 5A |