methylbenzethonium chloride-3850 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the methylbenzethonium chloride-3850 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADGRG1 adhesion G protein-coupled receptor G1
ADORA1 adenosine A1 receptor
AKAP1 A kinase (PRKA) anchor protein 1
ALDOB aldolase B, fructose-bisphosphate
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
BCL3 B-cell CLL/lymphoma 3
BDKRB2 bradykinin receptor B2
C5AR1 complement component 5a receptor 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC64 coiled-coil domain containing 64
CCNG2 cyclin G2
CD34 CD34 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CGA glycoprotein hormones, alpha polypeptide
CLGN calmegin
COL13A1 collagen, type XIII, alpha 1
CSNK1G1 casein kinase 1, gamma 1
CUL7 cullin 7
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DAPK3 death-associated protein kinase 3
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
EGR1 early growth response 1
ESR1 estrogen receptor 1
EZR ezrin
FCMR Fc fragment of IgM receptor
GAS2L1 growth arrest-specific 2 like 1
GEM GTP binding protein overexpressed in skeletal muscle
GPER1 G protein-coupled estrogen receptor 1
GSN gelsolin
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IFT27 intraflagellar transport 27
IL21R interleukin 21 receptor
KHK ketohexokinase (fructokinase)
KITLG KIT ligand
KLHL24 kelch-like family member 24
KLHL25 kelch-like family member 25
LOXL2 lysyl oxidase-like 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K7 mitogen-activated protein kinase kinase 7
MMP11 matrix metallopeptidase 11
MT1F metallothionein 1F
NAT6 N-acetyltransferase 6 (GCN5-related)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEU3 sialidase 3 (membrane sialidase)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUPR1 nuclear protein, transcriptional regulator, 1
OSMR oncostatin M receptor
PARM1 prostate androgen-regulated mucin-like protein 1
PDE4C phosphodiesterase 4C, cAMP-specific
PGLYRP4 peptidoglycan recognition protein 4
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLK3 polo-like kinase 3
PRKD1 protein kinase D1
PSCA prostate stem cell antigen
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
PTAFR platelet-activating factor receptor
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCAN3 RCAN family member 3
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL2 ret finger protein-like 2
RGS14 regulator of G-protein signaling 14
RHAG Rh-associated glycoprotein
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SAG S-antigen; retina and pineal gland (arrestin)
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SOX4 SRY (sex determining region Y)-box 4
SP1 Sp1 transcription factor
SVIL supervillin
SWAP70 SWAP switching B-cell complex 70kDa subunit
SZT2 seizure threshold 2 homolog (mouse)
TAPBP TAP binding protein (tapasin)
TBC1D22B TBC1 domain family, member 22B
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBX3 T-box 3
TEX14 testis expressed 14
TIMP3 TIMP metallopeptidase inhibitor 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPSG1 tryptase gamma 1
TRAF4 TNF receptor-associated factor 4
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
WASL Wiskott-Aldrich syndrome-like
WNT16 wingless-type MMTV integration site family, member 16
ZFAND5 zinc finger, AN1-type domain 5
ZFX zinc finger protein, X-linked
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
AMH anti-Mullerian hormone
AMPD1 adenosine monophosphate deaminase 1
ANKH ANKH inorganic pyrophosphate transport regulator
ARMC4 armadillo repeat containing 4
ARR3 arrestin 3, retinal (X-arrestin)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C10ORF95 chromosome 10 open reading frame 95
C11ORF30 chromosome 11 open reading frame 30
C4BPA complement component 4 binding protein, alpha
CCDC69 coiled-coil domain containing 69
CD80 CD80 molecule
CFD complement factor D (adipsin)
CNGB3 cyclic nucleotide gated channel beta 3
CORO7 coronin 7
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DCAF4 DDB1 and CUL4 associated factor 4
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DUSP2 dual specificity phosphatase 2
DUSP9 dual specificity phosphatase 9
ELSPBP1 epididymal sperm binding protein 1
EMCN endomucin
EMID1 EMI domain containing 1
ENO3 enolase 3 (beta, muscle)
ERN1 endoplasmic reticulum to nucleus signaling 1
FANCE Fanconi anemia, complementation group E
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
GK3P glycerol kinase 3 pseudogene
GPR143 G protein-coupled receptor 143
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IL12RB1 interleukin 12 receptor, beta 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKB inositol-trisphosphate 3-kinase B
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL21 kelch-like family member 21
LHX1 LIM homeobox 1
LOXL3 lysyl oxidase-like 3
MLYCD malonyl-CoA decarboxylase
MTA2 metastasis associated 1 family, member 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDE1 nudE neurodevelopment protein 1
NES nestin
NPIPB15 nuclear pore complex interacting protein family, member B15
NPPA natriuretic peptide A
NSUN6 NOP2/Sun domain family, member 6
NXPH4 neurexophilin 4
OTUD3 OTU deubiquitinase 3
PCDH17 protocadherin 17
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PPT2 palmitoyl-protein thioesterase 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RAB36 RAB36, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM14 RNA binding motif protein 14
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL10L ribosomal protein L10-like
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A9 S100 calcium binding protein A9
SCGB2A2 secretoglobin, family 2A, member 2
SCML2 sex comb on midleg-like 2 (Drosophila)
SDC3 syndecan 3
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPON2 spondin 2, extracellular matrix protein
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THRAP3 thyroid hormone receptor associated protein 3
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UNC93B1 unc-93 homolog B1 (C. elegans)
WDR62 WD repeat domain 62
ZBED1 zinc finger, BED-type containing 1
ZDHHC14 zinc finger, DHHC-type containing 14
ZMAT4 zinc finger, matrin-type 4
ZNF358 zinc finger protein 358
ZNF365 zinc finger protein 365
ZNF532 zinc finger protein 532
ZNF557 zinc finger protein 557
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76
ZSCAN2 zinc finger and SCAN domain containing 2