| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the methyldopa-1619 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AGRP | agouti related neuropeptide |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ATP10A | ATPase, class V, type 10A |
| AXIN1 | axin 1 |
| BCAP29 | B-cell receptor-associated protein 29 |
| BMP7 | bone morphogenetic protein 7 |
| BPI | bactericidal/permeability-increasing protein |
| C20ORF27 | chromosome 20 open reading frame 27 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCR1 | chemokine (C-C motif) receptor 1 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COQ4 | coenzyme Q4 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CYB561 | cytochrome b561 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| EGR3 | early growth response 3 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| ENOSF1 | enolase superfamily member 1 |
| FAM188A | family with sequence similarity 188, member A |
| FANCF | Fanconi anemia, complementation group F |
| FASTK | Fas-activated serine/threonine kinase |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GAB2 | GRB2-associated binding protein 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GSDMD | gasdermin D |
| GSS | glutathione synthetase |
| HFE | hemochromatosis |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| ICAM3 | intercellular adhesion molecule 3 |
| IDS | iduronate 2-sulfatase |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| ITGA7 | integrin, alpha 7 |
| KHK | ketohexokinase (fructokinase) |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LAD1 | ladinin 1 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MCAM | melanoma cell adhesion molecule |
| MEF2D | myocyte enhancer factor 2D |
| MTRF1L | mitochondrial translational release factor 1-like |
| N4BP1 | NEDD4 binding protein 1 |
| NCOA3 | nuclear receptor coactivator 3 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) |
| NPPA | natriuretic peptide A |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PICK1 | protein interacting with PRKCA 1 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PIK3CG | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
| PKN1 | protein kinase N1 |
| POGZ | pogo transposable element with ZNF domain |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRPF6 | pre-mRNA processing factor 6 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PTMA | prothymosin, alpha |
| RAB28 | RAB28, member RAS oncogene family |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RPS11 | ribosomal protein S11 |
| RRBP1 | ribosome binding protein 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| SPN | sialophorin |
| SRGN | serglycin |
| THTPA | thiamine triphosphatase |
| TMEM127 | transmembrane protein 127 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VILL | villin-like |
| WDR62 | WD repeat domain 62 |
| WWC3 | WWC family member 3 |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF160 | zinc finger protein 160 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG101 | autophagy related 101 |
| ATP11B | ATPase, class VI, type 11B |
| BCL7B | B-cell CLL/lymphoma 7B |
| BCOR | BCL6 corepressor |
| BEX1 | brain expressed, X-linked 1 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C1ORF123 | chromosome 1 open reading frame 123 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CD302 | CD302 molecule |
| CDK8 | cyclin-dependent kinase 8 |
| CENPC | centromere protein C |
| CLDN15 | claudin 15 |
| COQ9 | coenzyme Q9 |
| CPOX | coproporphyrinogen oxidase |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide |
| DDA1 | DET1 and DDB1 associated 1 |
| DEXI | Dexi homolog (mouse) |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit |
| ELP4 | elongator acetyltransferase complex subunit 4 |
| EMC6 | ER membrane protein complex subunit 6 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FAM117A | family with sequence similarity 117, member A |
| FTO | fat mass and obesity associated |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GPATCH2 | G patch domain containing 2 |
| GPS1 | G protein pathway suppressor 1 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GTF3C4 | general transcription factor IIIC, polypeptide 4, 90kDa |
| HYOU1 | hypoxia up-regulated 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0196 | KIAA0196 |
| KIAA1551 | KIAA1551 |
| KIFC1 | kinesin family member C1 |
| LAP3 | leucine aminopeptidase 3 |
| MAEA | macrophage erythroblast attacher |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MOAP1 | modulator of apoptosis 1 |
| MOSPD1 | motile sperm domain containing 1 |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MRPS15 | mitochondrial ribosomal protein S15 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MUTYH | mutY homolog |
| MXRA7 | matrix-remodelling associated 7 |
| NAGK | N-acetylglucosamine kinase |
| NCSTN | nicastrin |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NMD3 | NMD3 ribosome export adaptor |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NUBP1 | nucleotide binding protein 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RX1 | purinergic receptor P2X, ligand gated ion channel, 1 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDHX | pyruvate dehydrogenase complex, component X |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RAB1B | RAB1B, member RAS oncogene family |
| RBM28 | RNA binding motif protein 28 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| SAE1 | SUMO1 activating enzyme subunit 1 |
| SAMHD1 | SAM domain and HD domain 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIRT1 | sirtuin 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNX10 | sorting nexin 10 |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| TBL3 | transducin (beta)-like 3 |
| TMEM106B | transmembrane protein 106B |
| TMEM184C | transmembrane protein 184C |
| TOM1L1 | target of myb1 (chicken)-like 1 |
| TPCN1 | two pore segment channel 1 |
| TSPAN14 | tetraspanin 14 |
| TTC17 | tetratricopeptide repeat domain 17 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USP8 | ubiquitin specific peptidase 8 |
| USPL1 | ubiquitin specific peptidase like 1 |
| UTP11L | UTP11-like, U3 small nucleolar ribonucleoprotein (yeast) |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WRN | Werner syndrome, RecQ helicase-like |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZNF140 | zinc finger protein 140 |
