| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the methyldopa-3234 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ACRV1 | acrosomal vesicle protein 1 |
| ADCK2 | aarF domain containing kinase 2 |
| ADRA1A | adrenoceptor alpha 1A |
| AIM1L | absent in melanoma 1-like |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF15 | Rho guanine nucleotide exchange factor (GEF) 15 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| B9D2 | B9 protein domain 2 |
| CA12 | carbonic anhydrase XII |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DUOX1 | dual oxidase 1 |
| EDN2 | endothelin 2 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM76A | family with sequence similarity 76, member A |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLJ11292 | |
| FZD10 | frizzled class receptor 10 |
| GAS7 | growth arrest-specific 7 |
| GGT1 | gamma-glutamyltransferase 1 |
| GMPR | guanosine monophosphate reductase |
| GPATCH4 | G patch domain containing 4 |
| GPR68 | G protein-coupled receptor 68 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIPK2 | homeodomain interacting protein kinase 2 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IGL | immunoglobulin lambda locus |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KIF21B | kinesin family member 21B |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LILRP2 | leukocyte immunoglobulin-like receptor pseudogene 2 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC51145 | uncharacterized LOC51145 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAP2 | microtubule-associated protein 2 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MDFI | MyoD family inhibitor |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MT4 | metallothionein 4 |
| MX1 | MX dynamin-like GTPase 1 |
| MYOD1 | myogenic differentiation 1 |
| NOTCH4 | notch 4 |
| NPAS2 | neuronal PAS domain protein 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OVOL2 | ovo-like zinc finger 2 |
| PARK2 | parkin RBR E3 ubiquitin protein ligase |
| PDE10A | phosphodiesterase 10A |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDPN | podoplanin |
| PGAM2 | phosphoglycerate mutase 2 (muscle) |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PKLR | pyruvate kinase, liver and RBC |
| PORCN | porcupine homolog (Drosophila) |
| PRMT8 | protein arginine methyltransferase 8 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| R3HDM1 | R3H domain containing 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RORB | RAR-related orphan receptor B |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPL7 | ribosomal protein L7 |
| RPS11 | ribosomal protein S11 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC19A3 | solute carrier family 19 (thiamine transporter), member 3 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC6A9 | solute carrier family 6 (neurotransmitter transporter, glycine), member 9 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLFN12 | schlafen family member 12 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPX | spexin hormone |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STATH | statherin |
| TGFB2 | transforming growth factor, beta 2 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TSKS | testis-specific serine kinase substrate |
| UPP1 | uridine phosphorylase 1 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF280A | zinc finger protein 280A |
| ZNF343 | zinc finger protein 343 |
| ZNF442 | zinc finger protein 442 |
| ZNF589 | zinc finger protein 589 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AEN | apoptosis enhancing nuclease |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARRB1 | arrestin, beta 1 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCNL2 | cyclin L2 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EMID1 | EMI domain containing 1 |
| EXOC5 | exocyst complex component 5 |
| FAAH | fatty acid amide hydrolase |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GALK1 | galactokinase 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLI3 | GLI family zinc finger 3 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HOXC10 | homeobox C10 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYZ | lysozyme |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MPI | mannose phosphate isomerase |
| MTMR12 | myotubularin related protein 12 |
| MYO1E | myosin IE |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARD6B | par-6 family cell polarity regulator beta |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| RGS17 | regulator of G-protein signaling 17 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF141 | ring finger protein 141 |
| RNF170 | ring finger protein 170 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SDC3 | syndecan 3 |
| SEC24B | SEC24 family member B |
| SETD1A | SET domain containing 1A |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SIK1 | salt-inducible kinase 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SYCP2 | synaptonemal complex protein 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TDRD1 | tudor domain containing 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TFIP11 | tuftelin interacting protein 11 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM183A | transmembrane protein 183A |
| TTBK2 | tau tubulin kinase 2 |
| ULBP2 | UL16 binding protein 2 |
| USP19 | ubiquitin specific peptidase 19 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WRN | Werner syndrome, RecQ helicase-like |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF211 | zinc finger protein 211 |
| ZNF250 | zinc finger protein 250 |
| ZNF552 | zinc finger protein 552 |
| ZNF696 | zinc finger protein 696 |
| ZNF778 | zinc finger protein 778 |
| ZW10 | zw10 kinetochore protein |
