| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the methyldopa-4677 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ACVR1B | activin A receptor, type IB |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| C17ORF70 | chromosome 17 open reading frame 70 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CD7 | CD7 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP152 | centrosomal protein 152kDa |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC4E | C-type lectin domain family 4, member E |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| FAM3A | family with sequence similarity 3, member A |
| GALT | galactose-1-phosphate uridylyltransferase |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HEMK1 | HemK methyltransferase family member 1 |
| HSF1 | heat shock transcription factor 1 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL11 | interleukin 11 |
| IL1RN | interleukin 1 receptor antagonist |
| IL22 | interleukin 22 |
| IQCC | IQ motif containing C |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCNQ2 | potassium channel, voltage gated KQT-like subfamily Q, member 2 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KIF13A | kinesin family member 13A |
| LPIN1 | lipin 1 |
| LRRC32 | leucine rich repeat containing 32 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MTCP1 | mature T-cell proliferation 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PAQR5 | progestin and adipoQ receptor family member V |
| PAX9 | paired box 9 |
| PCDHB3 | protocadherin beta 3 |
| PCNX | pecanex homolog (Drosophila) |
| PDS5A | PDS5 cohesin associated factor A |
| PER1 | period circadian clock 1 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PROX1 | prospero homeobox 1 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PVR | poliovirus receptor |
| RAB11B | RAB11B, member RAS oncogene family |
| RAD51D | RAD51 paralog D |
| RGS5 | regulator of G-protein signaling 5 |
| RNF8 | ring finger protein 8, E3 ubiquitin protein ligase |
| RPS14 | ribosomal protein S14 |
| RUNX1 | runt-related transcription factor 1 |
| RYK | receptor-like tyrosine kinase |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SEMA4F | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| SMAD3 | SMAD family member 3 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX30 | SRY (sex determining region Y)-box 30 |
| STK17B | serine/threonine kinase 17b |
| STOML1 | stomatin (EPB72)-like 1 |
| STX7 | syntaxin 7 |
| SUSD4 | sushi domain containing 4 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBC1D2B | TBC1 domain family, member 2B |
| TBL2 | transducin (beta)-like 2 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TFEB | transcription factor EB |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFA | transforming growth factor, alpha |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TNS1 | tensin 1 |
| TRIM3 | tripartite motif containing 3 |
| TTC30A | tetratricopeptide repeat domain 30A |
| UTP18 | UTP18 small subunit (SSU) processome component homolog (yeast) |
| VGLL3 | vestigial-like family member 3 |
| ZNF268 | zinc finger protein 268 |
| ZNF34 | zinc finger protein 34 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF391 | zinc finger protein 391 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ALB | albumin |
| ANXA2P1 | annexin A2 pseudogene 1 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ATP1A3 | ATPase, Na+/K+ transporting, alpha 3 polypeptide |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C1RL | complement component 1, r subcomponent-like |
| CD68 | CD68 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRLF1 | cytokine receptor-like factor 1 |
| CXORF56 | chromosome X open reading frame 56 |
| CYBRD1 | cytochrome b reductase 1 |
| DSPP | dentin sialophosphoprotein |
| FAM131A | family with sequence similarity 131, member A |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD8 | FERM domain containing 8 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR27 | G protein-coupled receptor 27 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BO | histone cluster 1, H2bo |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| HOXA7 | homeobox A7 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT54 | intraflagellar transport 54 |
| IL6 | interleukin 6 |
| IL7 | interleukin 7 |
| ITGB7 | integrin, beta 7 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KIAA0895 | KIAA0895 |
| KLF13 | Kruppel-like factor 13 |
| KRT31 | keratin 31, type I |
| LAMC3 | laminin, gamma 3 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMTK1 | lemur tail kinase 1 |
| LOC157562 | uncharacterized LOC157562 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MRPL44 | mitochondrial ribosomal protein L44 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MYOZ3 | myozenin 3 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NAG18 | NAG18 mRNA |
| NEUROD4 | neuronal differentiation 4 |
| NOL10 | nucleolar protein 10 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OLFM4 | olfactomedin 4 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRF1 | perforin 1 (pore forming protein) |
| PRSS53 | protease, serine, 53 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SYNGR3 | synaptogyrin 3 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TMEM212 | transmembrane protein 212 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| WDR25 | WD repeat domain 25 |
| XAB2 | XPA binding protein 2 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF205 | zinc finger protein 205 |
| ZNF428 | zinc finger protein 428 |
| ZNF76 | zinc finger protein 76 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
