| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the methyldopa-5272 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| APOM | apolipoprotein M |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BEX1 | brain expressed, X-linked 1 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| CA9 | carbonic anhydrase IX |
| CARD14 | caspase recruitment domain family, member 14 |
| CCDC28B | coiled-coil domain containing 28B |
| CCDC7 | coiled-coil domain containing 7 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD6 | CD6 molecule |
| CD82 | CD82 molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CLDN11 | claudin 11 |
| CLPS | colipase, pancreatic |
| CLUH | clustered mitochondria (cluA/CLU1) homolog |
| COL1A2 | collagen, type I, alpha 2 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CT62 | cancer/testis antigen 62 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| CXORF21 | chromosome X open reading frame 21 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DOCK5 | dedicator of cytokinesis 5 |
| DOK4 | docking protein 4 |
| DTNB | dystrobrevin, beta |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| FAM46C | family with sequence similarity 46, member C |
| FGF18 | fibroblast growth factor 18 |
| FKRP | fukutin related protein |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GLYAT | glycine-N-acyltransferase |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GOLGA8A | golgin A8 family, member A |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HRH2 | histamine receptor H2 |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| IFT27 | intraflagellar transport 27 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| ISG20L2 | interferon stimulated exonuclease gene 20kDa-like 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNK2 | potassium channel, two pore domain subfamily K, member 2 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LOXL2 | lysyl oxidase-like 2 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MEF2D | myocyte enhancer factor 2D |
| MMP25 | matrix metallopeptidase 25 |
| MYO15A | myosin XVA |
| NLGN1 | neuroligin 1 |
| NOL12 | nucleolar protein 12 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| ONECUT1 | one cut homeobox 1 |
| PADI3 | peptidyl arginine deiminase, type III |
| PER2 | period circadian clock 2 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLK3 | polo-like kinase 3 |
| PML | promyelocytic leukemia |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRAMEF10 | PRAME family member 10 |
| PTPRD | protein tyrosine phosphatase, receptor type, D |
| PYY | peptide YY |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RGS12 | regulator of G-protein signaling 12 |
| RUNX1 | runt-related transcription factor 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDC3 | syndecan 3 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STK24 | serine/threonine kinase 24 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SYN2 | synapsin II |
| SYNDIG1 | synapse differentiation inducing 1 |
| SYT11 | synaptotagmin XI |
| TLR4 | toll-like receptor 4 |
| TMEM74B | transmembrane protein 74B |
| UBXN1 | UBX domain protein 1 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF44 | zinc finger protein 44 |
| ZNF440 | zinc finger protein 440 |
| ZNF551 | zinc finger protein 551 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AES | amino-terminal enhancer of split |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALS2CL | ALS2 C-terminal like |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BMP15 | bone morphogenetic protein 15 |
| BMP4 | bone morphogenetic protein 4 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLDN15 | claudin 15 |
| CLSPN | claspin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORT | cortistatin |
| CRY2 | cryptochrome circadian clock 2 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DRD1 | dopamine receptor D1 |
| DSCAM | Down syndrome cell adhesion molecule |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FGF13 | fibroblast growth factor 13 |
| GAMT | guanidinoacetate N-methyltransferase |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GK3P | glycerol kinase 3 pseudogene |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRB7 | growth factor receptor-bound protein 7 |
| GUCY1A2 | guanylate cyclase 1, soluble, alpha 2 |
| HIST1H1D | histone cluster 1, H1d |
| HOXC8 | homeobox C8 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFT54 | intraflagellar transport 54 |
| IL22 | interleukin 22 |
| IL4R | interleukin 4 receptor |
| IRF1 | interferon regulatory factor 1 |
| KIF5A | kinesin family member 5A |
| KLHL28 | kelch-like family member 28 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC729164 | hCG1732469 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP6D1 | MAP6 domain containing 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| MTCP1 | mature T-cell proliferation 1 |
| MYO1E | myosin IE |
| MYO1F | myosin IF |
| N4BP3 | NEDD4 binding protein 3 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OVOL1 | ovo-like zinc finger 1 |
| PARPBP | PARP1 binding protein |
| PCDHB13 | protocadherin beta 13 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIPOX | pipecolic acid oxidase |
| PITX1 | paired-like homeodomain 1 |
| PLA2G10 | phospholipase A2, group X |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRPH | peripherin |
| RAB36 | RAB36, member RAS oncogene family |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RGS2 | regulator of G-protein signaling 2 |
| RNF121 | ring finger protein 121 |
| S100A7 | S100 calcium binding protein A7 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIX1 | SIX homeobox 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP1 | Sp1 transcription factor |
| STBD1 | starch binding domain 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TCTN2 | tectonic family member 2 |
| TEX40 | testis expressed 40 |
| TFF2 | trefoil factor 2 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM242 | transmembrane protein 242 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSGA10 | testis specific, 10 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VPS9D1 | VPS9 domain containing 1 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF34 | zinc finger protein 34 |
| ZNF428 | zinc finger protein 428 |
| ZNF750 | zinc finger protein 750 |
