| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the methyldopa-5637 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC8 | ATP-binding cassette, sub-family C (CFTR/MRP), member 8 |
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ARTN | artemin |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BTG2 | BTG family, member 2 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CDC14B | cell division cycle 14B |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CFHR2 | complement factor H-related 2 |
| CFHR4 | complement factor H-related 4 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLTA | clathrin, light chain A |
| COL2A1 | collagen, type II, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DGKQ | diacylglycerol kinase, theta 110kDa |
| DMPK | dystrophia myotonica-protein kinase |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| ESR1 | estrogen receptor 1 |
| EVI5 | ecotropic viral integration site 5 |
| FAM46C | family with sequence similarity 46, member C |
| FAM76A | family with sequence similarity 76, member A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGF13 | fibroblast growth factor 13 |
| GAS7 | growth arrest-specific 7 |
| GK | glycerol kinase |
| GOLGA8A | golgin A8 family, member A |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HFE | hemochromatosis |
| HOXB3 | homeobox B3 |
| HOXD9 | homeobox D9 |
| IFT27 | intraflagellar transport 27 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL1RN | interleukin 1 receptor antagonist |
| INHBE | inhibin, beta E |
| IZUMO4 | IZUMO family member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNAB3 | potassium channel, voltage gated subfamily A regulatory beta subunit 3 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KHK | ketohexokinase (fructokinase) |
| KLK13 | kallikrein-related peptidase 13 |
| KRT8 | keratin 8, type II |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LENEP | lens epithelial protein |
| MAOB | monoamine oxidase B |
| MAPK8 | mitogen-activated protein kinase 8 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP25 | matrix metallopeptidase 25 |
| MNDA | myeloid cell nuclear differentiation antigen |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| MXRA5 | matrix-remodelling associated 5 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NKX2-8 | NK2 homeobox 8 |
| NPAS2 | neuronal PAS domain protein 2 |
| PCDH11Y | protocadherin 11 Y-linked |
| PDIA2 | protein disulfide isomerase family A, member 2 |
| PEG3 | paternally expressed 3 |
| PLLP | plasmolipin |
| PLXNC1 | plexin C1 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
| PRMT2IP | PRMT2 interacting protein |
| PRR16 | proline rich 16 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PYY | peptide YY |
| RAB3B | RAB3B, member RAS oncogene family |
| RXRB | retinoid X receptor, beta |
| SHOX2 | short stature homeobox 2 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPPL2B | signal peptide peptidase like 2B |
| SPRR2B | small proline-rich protein 2B |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAPBP | TAP binding protein (tapasin) |
| TBC1D22A | TBC1 domain family, member 22A |
| TBX3 | T-box 3 |
| TMEM212 | transmembrane protein 212 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| UBQLN4 | ubiquilin 4 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| VEGFB | vascular endothelial growth factor B |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF442 | zinc finger protein 442 |
| ZNF682 | zinc finger protein 682 |
| Symbol | Name |
|---|---|
| ADAMTSL3 | ADAMTS-like 3 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| APOLD1 | apolipoprotein L domain containing 1 |
| AUTS2 | autism susceptibility candidate 2 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BMP4 | bone morphogenetic protein 4 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC71 | coiled-coil domain containing 71 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CES3 | carboxylesterase 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLGN | calmegin |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CRY2 | cryptochrome circadian clock 2 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EPX | eosinophil peroxidase |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETNK2 | ethanolamine kinase 2 |
| F2R | coagulation factor II (thrombin) receptor |
| FADS2 | fatty acid desaturase 2 |
| FAM204A | family with sequence similarity 204, member A |
| FILIP1L | filamin A interacting protein 1-like |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GFI1 | growth factor independent 1 transcription repressor |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GRAMD1C | GRAM domain containing 1C |
| HDAC11 | histone deacetylase 11 |
| HDAC5 | histone deacetylase 5 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HMHB1 | histocompatibility (minor) HB-1 |
| HOXC8 | homeobox C8 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HYI | hydroxypyruvate isomerase (putative) |
| IBSP | integrin-binding sialoprotein |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INO80D | INO80 complex subunit D |
| ITGA8 | integrin, alpha 8 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIF13B | kinesin family member 13B |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MAL | mal, T-cell differentiation protein |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MUC3A | mucin 3A, cell surface associated |
| MYO1F | myosin IF |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEUROD1 | neuronal differentiation 1 |
| NEUROD4 | neuronal differentiation 4 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPTX1 | neuronal pentraxin I |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE8B | phosphodiesterase 8B |
| PLA2G3 | phospholipase A2, group III |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POU4F2 | POU class 4 homeobox 2 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| RAB30 | RAB30, member RAS oncogene family |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| RNF43 | ring finger protein 43 |
| RPL10L | ribosomal protein L10-like |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SNX15 | sorting nexin 15 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBX19 | T-box 19 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMEM242 | transmembrane protein 242 |
| TMPRSS3 | transmembrane protease, serine 3 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| XDH | xanthine dehydrogenase |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZFP37 | ZFP37 zinc finger protein |
| ZNF484 | zinc finger protein 484 |
| ZNF711 | zinc finger protein 711 |
