| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the methyldopate-2940 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIF1 | allograft inflammatory factor 1 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ATXN2L | ataxin 2-like |
| AXIN1 | axin 1 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP6 | bone morphogenetic protein 6 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CDON | cell adhesion associated, oncogene regulated |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTN1 | contactin 1 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL5A2 | collagen, type V, alpha 2 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DMP1 | dentin matrix acidic phosphoprotein 1 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DRD2 | dopamine receptor D2 |
| ELN | elastin |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EPHB3 | EPH receptor B3 |
| F12 | coagulation factor XII (Hageman factor) |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FTCD | formimidoyltransferase cyclodeaminase |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GLP1R | glucagon-like peptide 1 receptor |
| GMPR | guanosine monophosphate reductase |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HAB1 | B1 for mucin |
| HCN4 | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HEYL | hes-related family bHLH transcription factor with YRPW motif-like |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| IGHM | immunoglobulin heavy constant mu |
| ING2 | inhibitor of growth family, member 2 |
| JMJD4 | jumonji domain containing 4 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| LMNA | lamin A/C |
| MVD | mevalonate (diphospho) decarboxylase |
| MYO6 | myosin VI |
| MYOF | myoferlin |
| NCS1 | neuronal calcium sensor 1 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NOP16 | NOP16 nucleolar protein |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NRAP | nebulin-related anchoring protein |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE8B | phosphodiesterase 8B |
| PGP | phosphoglycolate phosphatase |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PKLR | pyruvate kinase, liver and RBC |
| PLXNB2 | plexin B2 |
| PML | promyelocytic leukemia |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBP4 | retinol binding protein 4, plasma |
| RPL7 | ribosomal protein L7 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SETD1A | SET domain containing 1A |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| TCP1 | t-complex 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM187 | transmembrane protein 187 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TP53TG5 | TP53 target 5 |
| TPD52L1 | tumor protein D52-like 1 |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| TRIM3 | tripartite motif containing 3 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WWOX | WW domain containing oxidoreductase |
| ZNF407 | zinc finger protein 407 |
| ZNF460 | zinc finger protein 460 |
| ZNF580 | zinc finger protein 580 |
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AGBL5 | ATP/GTP binding protein-like 5 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMC7 | armadillo repeat containing 7 |
| ASGR2 | asialoglycoprotein receptor 2 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CEP70 | centrosomal protein 70kDa |
| CORO7 | coronin 7 |
| CPSF3L | cleavage and polyadenylation specific factor 3-like |
| CPTP | ceramide-1-phosphate transfer protein |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDA1 | DET1 and DDB1 associated 1 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EGR2 | early growth response 2 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM188A | family with sequence similarity 188, member A |
| GALE | UDP-galactose-4-epimerase |
| GID4 | GID complex subunit 4 |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GMIP | GEM interacting protein |
| GPATCH2 | G patch domain containing 2 |
| GPR65 | G protein-coupled receptor 65 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HPSE | heparanase |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIF24 | kinesin family member 24 |
| KLF13 | Kruppel-like factor 13 |
| KPTN | kaptin (actin binding protein) |
| LGALS9 | lectin, galactoside-binding, soluble, 9 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LOC157562 | uncharacterized LOC157562 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MAGEB2 | melanoma antigen family B2 |
| MAK | male germ cell-associated kinase |
| MANEA | mannosidase, endo-alpha |
| MAP1S | microtubule-associated protein 1S |
| MCOLN1 | mucolipin 1 |
| METTL16 | methyltransferase like 16 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MIR22HG | MIR22 host gene |
| MOCOS | molybdenum cofactor sulfurase |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARG | poly (ADP-ribose) glycohydrolase |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POLM | polymerase (DNA directed), mu |
| PYGB | phosphorylase, glycogen; brain |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RABL3 | RAB, member of RAS oncogene family-like 3 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RHOB | ras homolog family member B |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RWDD2A | RWD domain containing 2A |
| SECISBP2 | SECIS binding protein 2 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SLFN12 | schlafen family member 12 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| SPAG1 | sperm associated antigen 1 |
| SPRYD7 | SPRY domain containing 7 |
| STX1A | syntaxin 1A (brain) |
| TEC | tec protein tyrosine kinase |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| THBS3 | thrombospondin 3 |
| TMEM159 | transmembrane protein 159 |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| UNC13B | unc-13 homolog B (C. elegans) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF250 | zinc finger protein 250 |
| ZNF354A | zinc finger protein 354A |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
