| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the methyldopate-4986 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AHI1 | Abelson helper integration site 1 |
| AJAP1 | adherens junctions associated protein 1 |
| AK1 | adenylate kinase 1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APOE | apolipoprotein E |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BCL3 | B-cell CLL/lymphoma 3 |
| C1QB | complement component 1, q subcomponent, B chain |
| CAPN10 | calpain 10 |
| CCDC85C | coiled-coil domain containing 85C |
| CES3 | carboxylesterase 3 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNPY4 | canopy FGF signaling regulator 4 |
| CORO2B | coronin, actin binding protein, 2B |
| CSF1R | colony stimulating factor 1 receptor |
| CSNK1E | casein kinase 1, epsilon |
| DOK2 | docking protein 2, 56kDa |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EFNB3 | ephrin-B3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EHD1 | EH-domain containing 1 |
| ELK1 | ELK1, member of ETS oncogene family |
| EPHA1 | EPH receptor A1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM134B | family with sequence similarity 134, member B |
| FLJ42627 | uncharacterized LOC645644 |
| FOLR1 | folate receptor 1 (adult) |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FZD10 | frizzled class receptor 10 |
| GMPR | guanosine monophosphate reductase |
| GPM6B | glycoprotein M6B |
| GPR137 | G protein-coupled receptor 137 |
| HIRA | histone cell cycle regulator |
| HOMER3 | homer scaffolding protein 3 |
| HSF1 | heat shock transcription factor 1 |
| IDUA | iduronidase, alpha-L- |
| ING2 | inhibitor of growth family, member 2 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRF6 | interferon regulatory factor 6 |
| JAK3 | Janus kinase 3 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KLHL22 | kelch-like family member 22 |
| KLHL25 | kelch-like family member 25 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LAMC2 | laminin, gamma 2 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC157562 | uncharacterized LOC157562 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MCAM | melanoma cell adhesion molecule |
| MFAP3L | microfibrillar-associated protein 3-like |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MTA1 | metastasis associated 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHA5 | protocadherin alpha 5 |
| PCNX | pecanex homolog (Drosophila) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RNF122 | ring finger protein 122 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| RSU1 | Ras suppressor protein 1 |
| S100A2 | S100 calcium binding protein A2 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SIRT5 | sirtuin 5 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SYMPK | symplekin |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFBR1 | transforming growth factor, beta receptor 1 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TLR5 | toll-like receptor 5 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| UBOX5 | U-box domain containing 5 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WIZ | widely interspaced zinc finger motifs |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF362 | zinc finger protein 362 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALOX15 | arachidonate 15-lipoxygenase |
| AMT | aminomethyltransferase |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BMP15 | bone morphogenetic protein 15 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAGLA | diacylglycerol lipase, alpha |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DENND5B | DENN/MADD domain containing 5B |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DRD1 | dopamine receptor D1 |
| EFNA3 | ephrin-A3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EVPL | envoplakin |
| FAM155A | family with sequence similarity 155, member A |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FOXN2 | forkhead box N2 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GALK1 | galactokinase 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GPATCH2L | G patch domain containing 2-like |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HDAC5 | histone deacetylase 5 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| INO80D | INO80 complex subunit D |
| IRF9 | interferon regulatory factor 9 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT24 | keratin 24, type I |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC61 | leucine rich repeat containing 61 |
| LTC4S | leukotriene C4 synthase |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MED9 | mediator complex subunit 9 |
| METTL16 | methyltransferase like 16 |
| MFAP2 | microfibrillar-associated protein 2 |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSMR | oncostatin M receptor |
| OVOL1 | ovo-like zinc finger 1 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMCH | pro-melanin-concentrating hormone |
| RCAN3 | RCAN family member 3 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SIX1 | SIX homeobox 1 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC41A3 | solute carrier family 41, member 3 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCHH | trichohyalin |
| TCTN1 | tectonic family member 1 |
| TMEM242 | transmembrane protein 242 |
| TSPYL2 | TSPY-like 2 |
| TWF2 | twinfilin actin binding protein 2 |
| UCN | urocortin |
| UPK3B | uroplakin 3B |
| VASH1 | vasohibin 1 |
| VASH2 | vasohibin 2 |
| VLDLR | very low density lipoprotein receptor |
| VPS9D1 | VPS9 domain containing 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF16 | zinc finger protein 16 |
| ZNF428 | zinc finger protein 428 |
| ZNF442 | zinc finger protein 442 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF668 | zinc finger protein 668 |
