| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the methyldopate-6640 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| AAGAB | alpha- and gamma-adaptin binding protein |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BEX1 | brain expressed, X-linked 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| BTG2 | BTG family, member 2 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| C3AR1 | complement component 3a receptor 1 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CALHM2 | calcium homeostasis modulator 2 |
| CCDC132 | coiled-coil domain containing 132 |
| CD58 | CD58 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CIB2 | calcium and integrin binding family member 2 |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CYB561 | cytochrome b561 |
| CYTH1 | cytohesin 1 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| FBXO21 | F-box protein 21 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPATCH4 | G patch domain containing 4 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HSF1 | heat shock transcription factor 1 |
| IDS | iduronate 2-sulfatase |
| IGHM | immunoglobulin heavy constant mu |
| INO80B | INO80 complex subunit B |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQCK | IQ motif containing K |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDR | kinase insert domain receptor |
| KIAA0040 | KIAA0040 |
| KIAA0319L | KIAA0319-like |
| KLF12 | Kruppel-like factor 12 |
| KLHL22 | kelch-like family member 22 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRRC48 | leucine rich repeat containing 48 |
| METTL7A | methyltransferase like 7A |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRTN | neurturin |
| PAPPA2 | pappalysin 2 |
| PCDH9 | protocadherin 9 |
| PCDHA9 | protocadherin alpha 9 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PER2 | period circadian clock 2 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PLK4 | polo-like kinase 4 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPIAL4A | peptidylprolyl isomerase A (cyclophilin A)-like 4A |
| PRKCA | protein kinase C, alpha |
| PROL1 | proline rich, lacrimal 1 |
| PROX1 | prospero homeobox 1 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAB36 | RAB36, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RARG | retinoic acid receptor, gamma |
| RFPL3S | RFPL3 antisense |
| RHEB | Ras homolog enriched in brain |
| RNF122 | ring finger protein 122 |
| RPL35A | ribosomal protein L35a |
| RUNX1 | runt-related transcription factor 1 |
| SIRPA | signal-regulatory protein alpha |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPTB | spectrin, beta, erythrocytic |
| SRPK2 | SRSF protein kinase 2 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TJP3 | tight junction protein 3 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM231 | transmembrane protein 231 |
| TNP2 | transition protein 2 (during histone to protamine replacement) |
| USP6NL | USP6 N-terminal like |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| VCAN | versican |
| ZNF259P1 | zinc finger protein 259 pseudogene 1 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AK5 | adenylate kinase 5 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCNO | cyclin O |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CES3 | carboxylesterase 3 |
| CFHR2 | complement factor H-related 2 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTNAP1 | contactin associated protein 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CTSF | cathepsin F |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDN | dendrin |
| DNM3 | dynamin 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EVI2B | ecotropic viral integration site 2B |
| FAM13C | family with sequence similarity 13, member C |
| FAM53B | family with sequence similarity 53, member B |
| FGF23 | fibroblast growth factor 23 |
| FGL1 | fibrinogen-like 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GPR1 | G protein-coupled receptor 1 |
| HAMP | hepcidin antimicrobial peptide |
| HHAT | hedgehog acyltransferase |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BN | histone cluster 1, H2bn |
| HMOX1 | heme oxygenase 1 |
| HOXA4 | homeobox A4 |
| HOXB2 | homeobox B2 |
| IFNA14 | interferon, alpha 14 |
| IGSF6 | immunoglobulin superfamily, member 6 |
| IL12B | interleukin 12B |
| INO80D | INO80 complex subunit D |
| KIAA1456 | KIAA1456 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KRT24 | keratin 24, type I |
| LIFR | leukemia inhibitory factor receptor alpha |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MATN3 | matrilin 3 |
| MDFI | MyoD family inhibitor |
| MMP2 | matrix metallopeptidase 2 |
| MTMR12 | myotubularin related protein 12 |
| MYH15 | myosin, heavy chain 15 |
| MYOZ3 | myozenin 3 |
| NDRG4 | NDRG family member 4 |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPFFR1 | neuropeptide FF receptor 1 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OCA2 | oculocutaneous albinism II |
| OLFML3 | olfactomedin-like 3 |
| OSBP2 | oxysterol binding protein 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PLSCR2 | phospholipid scramblase 2 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PRDM14 | PR domain containing 14 |
| PRSS22 | protease, serine, 22 |
| RNF39 | ring finger protein 39 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC35F5 | solute carrier family 35, member F5 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAS2R10 | taste receptor, type 2, member 10 |
| TBC1D22B | TBC1 domain family, member 22B |
| TEP1 | telomerase-associated protein 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRIM25 | tripartite motif containing 25 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| YY2 | YY2 transcription factor |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF141 | zinc finger protein 141 |
| ZNF219 | zinc finger protein 219 |
| ZNF440 | zinc finger protein 440 |
| ZNF549 | zinc finger protein 549 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF711 | zinc finger protein 711 |
