| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the methyldopate-7360 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALS2CL | ALS2 C-terminal like |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG2A | autophagy related 2A |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD6 | CD6 molecule |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLEC11A | C-type lectin domain family 11, member A |
| CORO7 | coronin 7 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| DCTN1 | dynactin 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DSC3 | desmocollin 3 |
| DSCAM | Down syndrome cell adhesion molecule |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FADS2 | fatty acid desaturase 2 |
| FAM120C | family with sequence similarity 120C |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAM46C | family with sequence similarity 46, member C |
| FGF2 | fibroblast growth factor 2 (basic) |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOXI1 | forkhead box I1 |
| FRK | fyn-related Src family tyrosine kinase |
| GH1 | growth hormone 1 |
| GOLGA2 | golgin A2 |
| GPR107 | G protein-coupled receptor 107 |
| HBS1L | HBS1-like translational GTPase |
| HFE | hemochromatosis |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HMGA1 | high mobility group AT-hook 1 |
| HOMER3 | homer scaffolding protein 3 |
| IL1RN | interleukin 1 receptor antagonist |
| ITGB4 | integrin, beta 4 |
| JADE2 | jade family PHD finger 2 |
| KALRN | kalirin, RhoGEF kinase |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAP1A | microtubule-associated protein 1A |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MAP4 | microtubule-associated protein 4 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MED16 | mediator complex subunit 16 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MYOF | myoferlin |
| NAG18 | NAG18 mRNA |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NME5 | NME/NM23 family member 5 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PHF3 | PHD finger protein 3 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRDX2 | peroxiredoxin 2 |
| PRSS53 | protease, serine, 53 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RAB11B | RAB11B, member RAS oncogene family |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RECQL5 | RecQ protein-like 5 |
| RGS12 | regulator of G-protein signaling 12 |
| RPS2 | ribosomal protein S2 |
| S100A9 | S100 calcium binding protein A9 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3BP2 | SH3-domain binding protein 2 |
| SHOX2 | short stature homeobox 2 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SPRR1A | small proline-rich protein 1A |
| SSPN | sarcospan |
| STMN1 | stathmin 1 |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRIM3 | tripartite motif containing 3 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| VN1R1 | vomeronasal 1 receptor 1 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF442 | zinc finger protein 442 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATXN2 | ataxin 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CCDC186 | coiled-coil domain containing 186 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD82 | CD82 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLSTN2 | calsyntenin 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| COMMD10 | COMM domain containing 10 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CST6 | cystatin E/M |
| CXORF56 | chromosome X open reading frame 56 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP13 | dual specificity phosphatase 13 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYSF | dysferlin |
| EFNA3 | ephrin-A3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EMID1 | EMI domain containing 1 |
| FAM50B | family with sequence similarity 50, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH2L | G patch domain containing 2-like |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTT1 | glutathione S-transferase theta 1 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HDAC4 | histone deacetylase 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4D | histone cluster 1, H4d |
| HOXC10 | homeobox C10 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IPO8 | importin 8 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KIAA0754 | KIAA0754 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL25 | kelch-like family member 25 |
| LAMB3 | laminin, beta 3 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| LRRC49 | leucine rich repeat containing 49 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEK11 | NIMA-related kinase 11 |
| NPR3 | natriuretic peptide receptor 3 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLTP | phospholipid transfer protein |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POM121 | POM121 transmembrane nucleoporin |
| PROCR | protein C receptor, endothelial |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB3A | RAB3A, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RPL7A | ribosomal protein L7a |
| SCHIP1 | schwannomin interacting protein 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SPAG4 | sperm associated antigen 4 |
| SYCP2 | synaptonemal complex protein 2 |
| TESK1 | testis-specific kinase 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM209 | transmembrane protein 209 |
| TMEM51 | transmembrane protein 51 |
| TRAIP | TRAF interacting protein |
| TRIM25 | tripartite motif containing 25 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| UBOX5 | U-box domain containing 5 |
| VASH1 | vasohibin 1 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WDR4 | WD repeat domain 4 |
| WDR62 | WD repeat domain 62 |
| WDR76 | WD repeat domain 76 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF205 | zinc finger protein 205 |
| ZNF41 | zinc finger protein 41 |
| ZNF506 | zinc finger protein 506 |
| ZNF552 | zinc finger protein 552 |
