| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the methylergometrine-3222 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACOT11 | acyl-CoA thioesterase 11 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AFAP1 | actin filament associated protein 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| APC | adenomatous polyposis coli |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C3 | complement component 3 |
| CCKBR | cholecystokinin B receptor |
| CDHR2 | cadherin-related family member 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| COL9A3 | collagen, type IX, alpha 3 |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CTSF | cathepsin F |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYTH1 | cytohesin 1 |
| DCN | decorin |
| DMPK | dystrophia myotonica-protein kinase |
| DOCK6 | dedicator of cytokinesis 6 |
| EDA | ectodysplasin A |
| EMC1 | ER membrane protein complex subunit 1 |
| EPHA1 | EPH receptor A1 |
| ETV5 | ets variant 5 |
| FAM212B | family with sequence similarity 212, member B |
| FAS | Fas cell surface death receptor |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FN1 | fibronectin 1 |
| GABRA1 | gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
| GARNL3 | GTPase activating Rap/RanGAP domain-like 3 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GK | glycerol kinase |
| GLRA1 | glycine receptor, alpha 1 |
| GNMT | glycine N-methyltransferase |
| GPR21 | G protein-coupled receptor 21 |
| ICAM1 | intercellular adhesion molecule 1 |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| IL12B | interleukin 12B |
| IQCG | IQ motif containing G |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCND1 | potassium channel, voltage gated Shal related subfamily D, member 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| LIMK1 | LIM domain kinase 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LPIN1 | lipin 1 |
| LSP1 | lymphocyte-specific protein 1 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MMP11 | matrix metallopeptidase 11 |
| MVK | mevalonate kinase |
| MYO15A | myosin XVA |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NME5 | NME/NM23 family member 5 |
| NPAS3 | neuronal PAS domain protein 3 |
| NPR3 | natriuretic peptide receptor 3 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OTC | ornithine carbamoyltransferase |
| PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
| PCNX | pecanex homolog (Drosophila) |
| PEX16 | peroxisomal biogenesis factor 16 |
| RAB28 | RAB28, member RAS oncogene family |
| RETN | resistin |
| RPS11 | ribosomal protein S11 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SIRT5 | sirtuin 5 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLIT3 | slit homolog 3 (Drosophila) |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SLN | sarcolipin |
| SNX13 | sorting nexin 13 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPON2 | spondin 2, extracellular matrix protein |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STATH | statherin |
| TADA3 | transcriptional adaptor 3 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBXA2R | thromboxane A2 receptor |
| THBS1 | thrombospondin 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| UBXN1 | UBX domain protein 1 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF230 | zinc finger protein 230 |
| Symbol | Name |
|---|---|
| AARSD1 | alanyl-tRNA synthetase domain containing 1 |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BAX | BCL2-associated X protein |
| BFSP1 | beaded filament structural protein 1, filensin |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| DAGLA | diacylglycerol lipase, alpha |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DMTN | dematin actin binding protein |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EDAR | ectodysplasin A receptor |
| EMID1 | EMI domain containing 1 |
| EPHA2 | EPH receptor A2 |
| FADS2 | fatty acid desaturase 2 |
| FBXO31 | F-box protein 31 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GATA4 | GATA binding protein 4 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPATCH3 | G patch domain containing 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAMP | hepcidin antimicrobial peptide |
| HIRA | histone cell cycle regulator |
| HIST1H4F | histone cluster 1, H4f |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KITLG | KIT ligand |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMNB1 | lamin B1 |
| LPXN | leupaxin |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY6D | lymphocyte antigen 6 complex, locus D |
| LYPD1 | LY6/PLAUR domain containing 1 |
| LYZ | lysozyme |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MGC12488 | |
| MID1IP1 | MID1 interacting protein 1 |
| MT1H | metallothionein 1H |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLTP | phospholipid transfer protein |
| POR | P450 (cytochrome) oxidoreductase |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RGS20 | regulator of G-protein signaling 20 |
| SCAI | suppressor of cancer cell invasion |
| SDC3 | syndecan 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SETD1A | SET domain containing 1A |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TMSB15A | thymosin beta 15a |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNS2 | tensin 2 |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| WDR91 | WD repeat domain 91 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF227 | zinc finger protein 227 |
| ZNF329 | zinc finger protein 329 |
| ZNF669 | zinc finger protein 669 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
