| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the methylergometrine-6704 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ADGB | androglobin |
| AIM2 | absent in melanoma 2 |
| APC2 | adenomatosis polyposis coli 2 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ASPA | aspartoacylase |
| ATXN3L | ataxin 3-like |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C10ORF12 | chromosome 10 open reading frame 12 |
| CELSR2 | cadherin, EGF LAG seven-pass G-type receptor 2 |
| CISH | cytokine inducible SH2-containing protein |
| COL1A2 | collagen, type I, alpha 2 |
| CORO7 | coronin 7 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRYGD | crystallin, gamma D |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CST1 | cystatin SN |
| CTSF | cathepsin F |
| CUL3 | cullin 3 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| ELL | elongation factor RNA polymerase II |
| EXO5 | exonuclease 5 |
| FAM205BP | transmembrane protein C9orf144B pseudogene |
| FBXO21 | F-box protein 21 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FOXL1 | forkhead box L1 |
| GAN | gigaxonin |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM2 | glutamate receptor, metabotropic 2 |
| GYPB | glycophorin B (MNS blood group) |
| HEMK1 | HemK methyltransferase family member 1 |
| HFE | hemochromatosis |
| HOXC4 | homeobox C4 |
| HYAL1 | hyaluronoglucosaminidase 1 |
| ICOS | inducible T-cell co-stimulator |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KRT12 | keratin 12, type I |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LOXL2 | lysyl oxidase-like 2 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MED25 | mediator complex subunit 25 |
| MED27 | mediator complex subunit 27 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEK3 | NIMA-related kinase 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOX3 | NADPH oxidase 3 |
| NRF1 | nuclear respiratory factor 1 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PARP11 | poly (ADP-ribose) polymerase family, member 11 |
| PAWR | PRKC, apoptosis, WT1, regulator |
| PBOV1 | prostate and breast cancer overexpressed 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PLAC4 | placenta-specific 4 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM12 | PR domain containing 12 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| PROL1 | proline rich, lacrimal 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RIMS1 | regulating synaptic membrane exocytosis 1 |
| RNLS | renalase, FAD-dependent amine oxidase |
| RPL14 | ribosomal protein L14 |
| RS1 | retinoschisin 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLN | sarcolipin |
| SMAD1 | SMAD family member 1 |
| SPO11 | SPO11 meiotic protein covalently bound to DSB |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| SVIL | supervillin |
| TBX5 | T-box 5 |
| TIMELESS | timeless circadian clock |
| TLR4 | toll-like receptor 4 |
| TLR5 | toll-like receptor 5 |
| TLX2 | T-cell leukemia homeobox 2 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM246 | transmembrane protein 246 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRAC | T cell receptor alpha constant |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF234 | zinc finger protein 234 |
| ZNF268 | zinc finger protein 268 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALS2CL | ALS2 C-terminal like |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARRB2 | arrestin, beta 2 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BEX4 | brain expressed, X-linked 4 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHM | choroideremia (Rab escort protein 1) |
| CLDND1 | claudin domain containing 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CTSD | cathepsin D |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DMTN | dematin actin binding protein |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EML4 | echinoderm microtubule associated protein like 4 |
| EMP3 | epithelial membrane protein 3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| EXOC5 | exocyst complex component 5 |
| EXOSC5 | exosome component 5 |
| FAM50B | family with sequence similarity 50, member B |
| FANCC | Fanconi anemia, complementation group C |
| FAT4 | FAT atypical cadherin 4 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FNTB | farnesyltransferase, CAAX box, beta |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR176 | G protein-coupled receptor 176 |
| HIST1H2AM | histone cluster 1, H2am |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IREB2 | iron-responsive element binding protein 2 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIRREL | kin of IRRE like (Drosophila) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MCOLN1 | mucolipin 1 |
| MMP13 | matrix metallopeptidase 13 |
| MON1B | MON1 secretory trafficking family member B |
| MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| MYL9 | myosin, light chain 9, regulatory |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| OCLN | occludin |
| PAX9 | paired box 9 |
| PDE12 | phosphodiesterase 12 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB17 | RAB17, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| RMND1 | required for meiotic nuclear division 1 homolog (S. cerevisiae) |
| RNF146 | ring finger protein 146 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| S100A3 | S100 calcium binding protein A3 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SIK1 | salt-inducible kinase 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SPAG7 | sperm associated antigen 7 |
| STK16 | serine/threonine kinase 16 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM132A | transmembrane protein 132A |
| TMEM212 | transmembrane protein 212 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRABD | TraB domain containing |
| TRIM25 | tripartite motif containing 25 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TWISTNB | TWIST neighbor |
| USP32 | ubiquitin specific peptidase 32 |
| WDR25 | WD repeat domain 25 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF227 | zinc finger protein 227 |
| ZNF532 | zinc finger protein 532 |
| ZNF667 | zinc finger protein 667 |
